Untitled - D Ank Unlimited

Fagraeus–Wallbom, Astrid Elsa (1913–) 264 farmer’s lung
Native C3 (fluid-phase)
C3b fragment (bound)
iC3b fragment (bound)
C3c fragment (fluid-phase)
C3dg fragment (bound)
C3d fragment (bound)
C3a
Factor VIII—placenta
S – C = O
R
O
I
S–H C = O
β chain
β chain
S S S
S
β chain
S S S
S
β chain
α chain
α´ chain
antigens induce interleukin-1 (IL1) synthesis by alveolar
machrophages and facilitate increased secretion of tumor
necrosis factor-α (TNF-α) from alveolar macrophages
and monocytes, revealing cytokine participation in the
S
S
S
S
I
S–H
S–H
Trypsin
plasmin
or elastase
C3g
The binding of factor I to C3b.
S
S
R
O
C = O
R
O
C = O
S
S
R
O
S–H C = O
C3f
Astrid Elsa Fagraeus-Wallbom.
pathogenesis of hypersensitivity pneumonitis. Precipitin
antibodies are formed in a number of the subjects.
Fagraeus–Wallbom, Astrid Elsa (1913–)
Swedish investigator noted for her doctoral thesis that
provided the first clear evidence that immunoglobulins are
made in plasma cells. (Refer to Antibody Production in
Relation to the Development of Plasma Cells, 1948.)
familial Mediterranean fever (FMF)
An autoinflammatory primary immunodeficiency attrituable
to inheritated mutations of marenostrin, an inflammatory
regulator.
FANA
An abbreviation for fluorescent antinuclear antibody.
Farmer’s lung.
farmer’s lung
A pulmonary disease of farm workers who are exposed
repeatedly to organic dust and fungi such as the
Aspergillus species. It occurs as an extrinsic allergic
alveolitis or hypersensitivity pneumonitis in nonatopic
subjects. It is mediated by IgG 1. Antibodies specific for
moldy hay, in which a number of fungi grow readily, are
manifest in 90% of individuals. These include Microspora
vulgaris and Micropolyspora faeni. The pathogenesis is
believed to involve a type III hypersensitivity mechanism
with the deposition of immune complexes in the lung. IgG
antibodies interact with large particles of inhaled allergen