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abzyme 4 accessory molecules<br />

Trypanosome<br />

abzyme<br />

The union of antibody and enzyme molecules to form a<br />

hybrid catalytic molecule. Specificity for a target antigen is<br />

provided through the antibody portion and for a catalytic<br />

function through the enzyme portion. Thus, these molecules<br />

have numerous potential uses. They are capable of catalyzing<br />

various chemical reactions and show great promise as protein-clearing<br />

antibodies, as in the dissolution of fibrin clots<br />

from occluded coronary arteries in myocardial infarction.<br />

acanthosis nigricans<br />

A condition in which the afflicted subject develops insulin<br />

receptor autoantibodies associated with insulin-resistant<br />

diabetes mellitus, as well as thickened and pigmented skin.<br />

+<br />

H Antigen<br />

β 1–3<br />

A Antigen<br />

β 1–3<br />

B Antigen<br />

β 1–3<br />

Ablastin<br />

β 1–4<br />

α 1–2<br />

β 1–4<br />

α 1–2 α 1–3<br />

β 1–3<br />

α 1–2<br />

α 1–3<br />

Ablastin.<br />

Trypanosome proliferation<br />

No Trypanosome proliferation<br />

= Erythrocyte<br />

= Galactose (Gal)<br />

= N-acetylglucosamine<br />

(GlcNac)<br />

= Fucose (Fuc)<br />

= N-acetylgalacotsamine<br />

(GalNAc)<br />

Chemical structures of A, B, and H antigens of the ABO blood group system.<br />

accessory cell<br />

A cell such as a dendritic or Langerhans’ cell, monocyte,<br />

or macrophage that facilitates T cell responses to protein<br />

antigens. B cells may also act as antigen-presenting cells,<br />

thereby serving an accessory cell function.<br />

accessory molecules<br />

Molecules other than the antigen receptor and major histocompatibility<br />

complex (MHC) that participate in cognitive,<br />

activation, and effector functions of T lymphocyte responsiveness.<br />

Adhesion molecules facilitating the interaction<br />

of T lymphocytes with other cells that signal transducing<br />

molecules that participate in T cell activation or migration<br />

are classified as accessory molecules. Other examples

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