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Untitled - D Ank Unlimited

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CD314 157 CD350<br />

CD314<br />

A 42-kDa antigen present on NK cells, CD8 + T cells, γδ T<br />

cells, and macrophages. It functions in NK cell activation.<br />

CD315<br />

A 135-kDa antigen present on megakaryocytes, hepatocytes,<br />

epithelial cells, and endothelial cells and is weakly<br />

expressed on B cells and monocytes. Its ligands are w/CD9<br />

and CD81.<br />

CD316<br />

A 62- to 78-kDa antigen present on T cells, B cells, NK<br />

cells, and hepatocytes. It inhibits tumor cell metastasis.<br />

CD317<br />

A 30- to 36-kDa antigen present on plasma cells, lymphoplasmacytoid<br />

cells, stromal cells, fibroblasts, and<br />

selected dendritic cells. It may play a role in pre-B cell<br />

growth.<br />

CD318<br />

An 80/140-kDa antigen present on hematopoietic stem cells,<br />

epithelial cells, and selected tumor cells. Its function is in<br />

adhesion.<br />

CD319<br />

A 66-kDa antigen present on NK cells, most T cells, activated<br />

B cells, and mature dendritic cells. It activates NK<br />

cytotoxicity and functions in adhesion.<br />

CD320<br />

An antigen present on follicular dendritic cells that stimulates<br />

B cell growth.<br />

CD321<br />

A 35- to 40-kDa antigen present on epithelial cells,<br />

endothelial cells, leukocytes, platelets, erythrocytes,<br />

lung, placenta, and kidney. It functions in cell adhesion,<br />

leukocyte migration, and epithelial barrier<br />

maintenance.<br />

CD322<br />

A 48-kDa antigen present on endothelial cells, high<br />

endothelial venules in tonsils and heart cells. It functions in<br />

cell adhesion and lymphocyte homing.<br />

CD324<br />

A 120-kDa antigen present on epithelial cells, keratinocytes,<br />

and trophoblasts. It functions in cell-to-cell and<br />

cell-to-matrix adhesion, tumor suppression, cell growth,<br />

and differentiation.<br />

CD325<br />

A 130-kDa antigen present on neurons, skeletal and cardiac<br />

myocytes, fibroblasts, epithelial cells, and pancreatic and<br />

liver cells. It functions in cell-to-cell and cell-to-matrix<br />

adhesion, cell growth, and differentiation.<br />

CD326<br />

A 40-kDa antigen present on epithelial cells, in low concentration<br />

on thy-c and T, and tumor cells. It inhibits cellular<br />

activation and inflammation.<br />

CD327<br />

An antigen present on B cells, placenta trophoblastic cells,<br />

and granulocytes that functions in adhesion.<br />

CD328<br />

A 65- to 75-kDa antigen present on NK cells, selected T<br />

cells, monocytes, and granulocytes that inhibits NK and T<br />

cell activity.<br />

CD329<br />

An antigen present on monocytes, selected NK cells, B and<br />

T cells, neutrophils, hepatocytes, and myeloid leukemic<br />

cells. It inhibits immune responses.<br />

CD331<br />

A 60, 110- to 160-kDa antigen broadly expressed on<br />

epithelial cells, endothelial cells, fibroblasts, mesenchymal<br />

cells, cardiac myocytes, and fetal tissues. It functions in cell<br />

growth and limb development.<br />

CD332<br />

A 135-kDa antigen present on brain, liver, prostate, kidney,<br />

lung, spinal cord, and fetal tissues. It functions in limb<br />

induction and craniofacial development.<br />

CD333<br />

A 115- to 135-kDa antigen present on brain, kidney, adult<br />

testis, and fetal small intestine cells. It functions in limb<br />

induction and craniofacial development.<br />

CD334<br />

An 88- to 110-kDa antigen present on kidney, liver, lung<br />

and pancreatic cells, lymphocytes, and macrophages. It<br />

functions in bone and muscle development and cancer progression<br />

and metastasis.<br />

CD335<br />

A 46-kDa antigen present on NK cells. It functions in NK<br />

cell activation.<br />

CD336<br />

A 44-kDa antigen present on activated NK cells that functions<br />

in NK cell activation.<br />

CD337<br />

A 30-kDa antigen present on NK cells that functions in NK<br />

cell activation.<br />

CD338<br />

A 72-kDa antigen present on liver, kidney, intestine, lung,<br />

endothelial cells, melanoma, placenta, selected stem cells,<br />

and selected drug-resistant tumors. It functions in absorption<br />

and excretion of certain xenobiotics.<br />

CD339<br />

A 134-kDa antigen present on bone marrow stromal cells,<br />

thymic epithelium, endothelial cells, Schwann cells, keratinocytes,<br />

ovarian, prostate, pancreatic, placenta and heart<br />

cells. It functions in cell fate decisions in hematopoiesis and<br />

cardiovascular development.<br />

CD340<br />

A 185-kDa antigen present on epithelial and endothelial<br />

cells, keratinocytes, hematopoietic stem cell subsets, fetal<br />

mesodermal cells, and extraembryonic tissues. It is overexpressed<br />

on many malignant cells. It functions in cell growth<br />

and differentiation, and tumor cell metastasis.<br />

CD344<br />

A 48- to 53-kDa antigen present on epithelial, endothelial<br />

and mesenchymal cells, myeloid progenitors, neuronal<br />

progenitors, and intestinal neurons. It functions in cell proliferation<br />

and differentiation, embryonic development, and<br />

retinal angiogenesis.<br />

CD349<br />

A 64-kDa antigen present on mesenchymal stem cells,<br />

neural precursors, mammary epithelial and brain cells, fetal<br />

testis, kidney, eye, and pancreas, and selected tumors. It<br />

functions in B cell development, hippocampal development,<br />

and tissue morphogenesis.<br />

CD350<br />

A 65-kDa antigen present on brain, embryo, kidney, liver,<br />

pancreas, placenta, mammary and lung epithelium, and<br />

selected tumors. It functions in development of limbs and<br />

the nervous system.<br />

C

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