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CD279 156 CD312<br />

CD279<br />

A 50- to 55-kDa antigen present on activated T cells and<br />

activated B cells that has a role in T cell tolerance, negative<br />

regulation.<br />

CD280<br />

A 180-kDa antigen present on fibroblasts, endothelial cells,<br />

macrophages, osteoclasts, osteocytes, and chondrocytes<br />

that has a role in remodeling uptake and degradation of<br />

collagen.<br />

CD281<br />

A 90-kDa antigen present on monocytes, macrophages,<br />

dendritic cells, and keratinocytes. It regulates TLR2 function.<br />

Also called TLR1.<br />

CD282<br />

An 86-kDa antigen present on monocytes, granulocytes,<br />

macrophages, dendritic cells, keratinocytes, and epithelial<br />

cells. It has a role in innate immune responses to some bacteria<br />

and mycoplasma pathogens. Also called TLR2.<br />

CD283<br />

A 120-kDa antigen present on dendritic cells, fibroblasts,<br />

and epithelial cells. It has a role in innate immune responses<br />

to viral pathogens. Also called TLR3.<br />

CD284<br />

A 110-kDa antigen present on monocytes, macrophages,<br />

endothelial cells, and epithelial cells that has a role in<br />

innate immune responses to gram-negative bacteria. Also<br />

called TLR4.<br />

CD286<br />

A 90-kDa antigen present on monocytes, macrophages,<br />

granulocytes, dendritic cells, and epithelial cells that has<br />

a role in innate immune responses to some bacteria and<br />

mycoplasma pathogens. Also called TLR6.<br />

CD288<br />

A 110-kDa antigen present on monocytes, macrophages,<br />

dendritic cells, neurons, and axons that has a role in antiviral<br />

immune responses, brain development, and hematopoiesis.<br />

Also called TLR8.<br />

CD289<br />

A 110-kDa antigen present on dendritic cells, B cells, and<br />

monocytes that has a role in innate immune responses to<br />

bacteria or viruses. Also called TLR9.<br />

CD290<br />

A 90-kDa antigen present on B cells and dendritic cells that<br />

functions as a coreceptor with TLR2. Also called TLR10.<br />

CD292<br />

A 55, 80-kDa antigen present on mesenchymal cells, epithelial<br />

cells, bone progenitors, neurons, chrondrocytes, skeletal<br />

muscles, and cardiac myocytes. It participates in kinase<br />

functions, anti-apoptosis, and embryogenesis.<br />

CDw293<br />

A 55, 80-kDa antigen present on mysenchymal cells, bone<br />

progenitors, chrondrocytes, epithelial cells, heart and kidney<br />

cells. It is a kinase regulating cartilage formation.<br />

CD294<br />

A 55- to 70-kDa antigen present on Th2 cells, basophils, and<br />

eosinophils. It regulates immune and inflammatory responses,<br />

induces Th2 cells, eosinophil and basophil migration.<br />

CD295<br />

A 132-kDa antigen present on hematopoietic cells, heart,<br />

placenta, liver, kidney, and pancreatic cells. It regulates<br />

fat metabolism, proliferative/anti-apoptotic T cells, and<br />

hematopoietic precursors.<br />

CD296<br />

A 36-kDa antigen present on neutrophils, heart cells and<br />

skeletal muscle. It transfers ADP-ribose to target proteins<br />

and regulates cellular metabolism.<br />

CD297<br />

A 36-kDa antigen expressed on Dombrock red blood cells,<br />

monocytes, macrophages, basophils, endothelial cells,<br />

intestinal cells, and ovarian cells. It functions in metabolism<br />

of Dombrock blood group antigen.<br />

CD298<br />

A 32-kDa antigen that is broadly expressed in the central<br />

nervous system and testis. A noncatalytic component of<br />

ATPase coupling exchange of Na + , K + .<br />

CD299<br />

A 45-kDa antigen present on endothelia of the liver and<br />

lymph nodes. Its ligands are ICAM-3 and HIV gp120, as<br />

well as hepatitis C virus and Ebola virus. It functions in T<br />

cell trafficking, HCV, EBOV, and HIV infection.<br />

CD300a<br />

A 34-kDa antigen present on monocytes and macrophages,<br />

neutrophils, dendritic cells, NK cells, mast cells, T cells,<br />

and B cells. Functions as inhibitory R.<br />

CD300c<br />

A 35-kDa antigen present on monocytes, macrophages, neutrophils,<br />

dendritic cells, NK cells, T cells, and B cells.<br />

CD300e<br />

An antigen present on monocytes, macrophages, and<br />

selected dendritic cells.<br />

CD301<br />

A 42-kDa antigen present on macrophages and immature<br />

dendritic cells. It functions in cell adhesion, macrophage<br />

migration, and cellular recognition.<br />

CD302<br />

A 30-kDa antigen present on monocytes, macrophages, and<br />

dendritic cells.<br />

CD303<br />

A 39-kDa antigen present on plasmacytoid dendritic cells<br />

that functions in antigen capture and inhibition of interferon<br />

α/β production.<br />

CD304<br />

A 103-kDa antigen present on dendritic cells, T cells, neurons,<br />

and endothelial cells that functions in angiogenesis,<br />

dendritic cell–T cell interaction, and neuritogenesis.<br />

CD305<br />

A 31-kDa antigen present on T cells, B cells, NK cells,<br />

dendritic cells, monocytes, and macrophages. It inhibits<br />

cellular activation and inflammation.<br />

CD306<br />

A 16-kDa antigen present on T cells and monocytes that<br />

inhibits cellular activation and inflammation.<br />

CD307<br />

An 83- to 107-kDa antigen present on B cells, germinal<br />

centers, and light zone B cells. It functions in IgR and may<br />

play a role in B cell activation and neoplasia.<br />

CD309<br />

A 195/235-kDa antigen present on endothelial cells, primitive<br />

stem cells, and some tumor cells that functions in<br />

angiogenesis.<br />

CD312<br />

A 90-kDa antigen present on macrophages, activated<br />

monocytes, dendritic, liver, and lung cells. It is involved in<br />

immune and inflammatory responses.

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