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Untitled - D Ank Unlimited

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CD93 151 CDw116<br />

CD93<br />

A 120-kDa antigen present on neutrophils, monocytes, and<br />

endothelial cells. Its function is unknown. Also called GR11.<br />

CD94<br />

A 43-kDa antigen present on natural killer (NK) cells and<br />

α/β, γ/δ, and T cell subsets. Its function is unknown. Also<br />

called KP43.<br />

CD94-NKG2 receptor<br />

A heterodimeric inhibitory receptor that regulates natural<br />

killer (NK) cell activation. It interacts with the nonclassical<br />

human leukocyte antigen (HLA) class I molecule, HLA-E.<br />

CD95<br />

A 42-kDa antigen present on myeloid and T lymphoblastoid<br />

cell lines as well as various other cell lines. It binds the<br />

TNF-like ligand and causes apoptosis. Also called APO-1<br />

or Fas.<br />

CD96<br />

A 160-kDa antigen present on activated T cells. Its function<br />

is unknown. Also called TACTILE (T cell activation incresed<br />

late expression).<br />

CD97<br />

A 74,80 89-kDa antigen present on activated cells. Its function<br />

is unknown. Also called GR1, GL-KDD/F12.<br />

CD98<br />

An 80,94-kDa heterodimeric antigen present on T cells<br />

and B cells (weak), monocytes (strong), natural killer (NK)<br />

cells, granulocytes, and most human cell lines. Its function<br />

is unknown. Also called 4F2 or 2F3.<br />

CD99<br />

A 32-kDa antigen present on peripheral blood lymphocytes<br />

and thymocytes. Also called MIC2 or E2.<br />

CD99 (HO36-1.1)<br />

Anti-CD99 mouse monoclonal antibody reacts with<br />

MIC-2 antigen present on the cell membranes of Ewing’s<br />

sarcoma and primitive peripheral neuroectodermal<br />

tumors (PNETs). It is also present on some bone marrow,<br />

lymph nodes, spleen, cortical thymocytes, granulosa cells<br />

of the ovary, most β cells, CNS ependymal cells, Sertoli’s<br />

cells of the testis, and a few endothelial cells. MIC-2<br />

has also been identified in lymphoblastic lymphoma,<br />

rhabdomyosarcoma, mesenchymal chondrosarcoma, and<br />

thymoma.<br />

CD99R<br />

A 32-kDa antigen present on B and T lymphocytes and<br />

some leukemias. Also called CD99 mAb restricted.<br />

CD100<br />

A 150-kDa antigen that has broad expression on hematopoietic<br />

cells. Its function is unknown. Also called BB18, A8, GR3.<br />

CDw101<br />

A 140-kDa antigen present on granulocytes and macrophages.<br />

Its function is unknown. Also called BB27, BA27, GR14.<br />

CD102<br />

A 60-kDa antigen present on resting lymphocytes, monocytes,<br />

and vascular endothelial cells (strongest). It binds<br />

CD11/CD18 (LFA-1) but not CD11β/CD18 (Mac-1). Also<br />

called ICAM-2.<br />

CD103<br />

A 150/25-kDa antigen present on hairy cell leukemia cells,<br />

intraepithelial lymphocytes (2 to 6%), and peripheral blood<br />

lymphocytes. It is the αE integrin. Also called HML-1, αE<br />

integrin, or α6.<br />

CD104<br />

A 220-kDa antigen present on epithelia, Schwann cells, and<br />

some tumor cells. It functions as a β 4 integrin. Also called<br />

β 4 integrin chain or β 4.<br />

CD105<br />

A 95-kDa homodimeric antigen present on endothelial<br />

cells, bone marrow cell subset, and in vitro activated<br />

macrophages. Its function is unknown although it may be a<br />

ligand for an integrin. Also called Endoglin, TGF B 1 and β 3<br />

receptor, and GR7.<br />

CD106<br />

A 100,110-kDa antigen present on endothelial cells that<br />

functions as an adhesion molecule. It is a ligand for VLA-4.<br />

Also called VCAM-1 or INCAM-110.<br />

CD107a<br />

A 110-kDa antigen present on activated platelets. Its function<br />

is unknown, but it is a lysosomal membrane protein<br />

translocated to the cell surface following activation.<br />

Also called LAMP-1 (lysosomal associated membrane<br />

protein-1).<br />

CD107b<br />

A 120-kDa antigen present on activated platelets. Its function<br />

is unknown, but it is a lysosomal membrane protein<br />

translocated to the cell surface following activation. Also<br />

called LAMP-2.<br />

CD108<br />

An 80-kDa antigen present on activated T cells in spleen<br />

and some stromal cells. Its function is unknown. Also<br />

called GR2.<br />

CDw109<br />

A 170/150-kDa antigen present on activated T cells, platelets,<br />

and endothelial cells. Its function is unknown. Also<br />

called platelet activation factor, 8A3, 7D1, GR56.<br />

CD110<br />

An 82- to 84-kDa antigen present on stem cell subsets,<br />

megakaryocytes, and platelets (very weak). Also called<br />

thrompoetin receptor or Mpl.<br />

CD111<br />

A 64- to 72-kDa antigen present on stem cell subsets, macrophages,<br />

and neutrophils. Commonly referred to as PRR/<br />

Nectin-1.<br />

CD112<br />

A 64- to 72-kDa antigen present on monocytes, neutrophils,<br />

and stem cell subsets. Also called PRR2/nectin-2.<br />

CD113<br />

Nothing yet assigned to this number.<br />

CD114<br />

A 95/139-kDa antigen present on granulocytes and monocytes.<br />

Also called G-CSF receptor.<br />

CD115<br />

A 150-kDa antigen present on monocytes, macrophages,<br />

and placenta. It is a macrophage colony-stimulating factor<br />

(M-CSF) receptor. Also called M-CSFR (macrophage<br />

colony-stimulating factor receptor), CSF-1R, or cFMS.<br />

CDw116<br />

A 75- to 85-kDa antigen present on monocytes, neutrophils,<br />

eosinophils, fibroblasts, and endothelial cells. It is a granulocyte–macrophage<br />

colony-stimulating factor (GM-CSF)<br />

receptor α chain. Also called GM-CSF R (granulocyte–<br />

macrophage colony-stimulating factor receptor) or HGM-<br />

CSFR.<br />

C

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