Untitled - D Ank Unlimited

actericidin 100 BALB/c mice
bactericidin
An agent such as an antibody or nonantibody substance in
blood plasma that destroys bacteria.
bacterin
A vaccine comprised of killed bacterial cells in suspension.
Inactivation is by either chemical or physical treatment.
bacteriolysin
An agent such as an antibody or other substance that
lyses bacteria.
bacteriolysis
The disruption of bacterial cells by such agents as antibody
and complement or lysozyme, causing the cells to release
their contents.
bacteriophage λ
λ bacteriophage.
bacteriophage neutralization test
Refer to phage neutralization assay.
Bacteroides immunity
Bacteroides fragilis has a capsular polysaccharide that
serves as a virulence factor that led to use of the polysaccharide
as a vaccine in rats. The vaccine produced excellent
antibody levels but did not prevent abscess formation.
In the rat model, the findings strongly point to the role of
T cells in the immune response to B. fragilis in abscess
prevention. Murine studies confirmed the rat findings and
demonstrated that immune T cells are antigen-specific.
Abscess formation and prevention in response to B. fragilis
are mediated by T cell mechanisms. Abscess formation
requires a precursor-type T cell. Prevention of abscess
requires T cells belonging to the suppressor phenotype
that communicate via a small polypeptide factor. These
cells are antigen-specific but not major histocompatibility
complex (MHC)-restricted.
T8
T4
T8
T4
T4
B
B
B
T4
Epithelium
T8
HEV
Parafollicular
area
Mp
T4
T8
T4
T8
T4
T4
Mp
B
B
T4
B
T4
T8
B
B
T4
B
B
B
T8
T4
B
Mp
Dome
T4
B
Lymphoid
follicle
BAFF
B lymphocyte activating factor that is a member of the
TNF family. A survival factor needed for the maturation of
splenic transitional T1 B cells into transitional T2 B cells.
BAFF is necessary for the appearance of mature B cells
in the periphery. BAFF signaling is believed to activate
NF-κB and induces Bcl-2 expression. Autoimmunity develops
in mice when BAFF is overexpressed, and elevated
serum levels of BAFF have been described in human
autoimmune diseases. It is produced mainly by monocytes,
macrophages, and dendritic cells, but not by B cells. Proinflammatory
stimuli stimulate its expression by macrophages.
It occurs as both a homotrimeric transmembrane
molecule and in a soluble homotrimeric form. It binds to
three receptors, BAFF-R, TACI, and BCMA.
bagassosis
Hypersensitivity among sugar cane workers to the
Thermoactinomyces saccharic fungus that thrives in the
pressings from sugar cane. The condition is expressed as
a hypersensitivity pneumonitis. Subjects develop type III
(Arthus reaction) hypersensitivity following inhalation of
dust from molding hot sugar cane bagasse.
Bak a
A normal human platelet (thrombocyte) antigen. Anti-Bak a
IgG antibody synthesized by a Bak a -negative pregnant
female may be passively transferred across the placenta to
induce immune thrombocytopenia in the neonate.
balancing selection
A form of evolutionary selection that maintains various
phenotypes such as MHC isoforms in a population.
BALB/c mice
An inbred white mouse strain that responds to an intraperitoneal
inoculation of mineral oil and Freund’s complete
adjuvant with a myeloproliferative reaction.
T8
B
B B
BALT.
T8
B
B
Mp
T4
T4
B
T4
B
T4
Mp
T8
B
Bronchial lumen
B
B
B
Mp
B
T4
T4
T8
T8
T4
B
T4
B
Mp
T4
T8
HEV
T4
B
T8
T8
B
T4
T4
T4
T4