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Soft Tissue Visualization Using a Highly Efficient Megavoltage Cone ...

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Figure 13 shows neck/chest MVCT axial, coronal and sagittal images that were acquired with<br />

receptors 1 and by delivering 13 cGy.<br />

Figure 13: Neck/chest MV CBCT with receptor 1 using 13cGy<br />

4. Summary<br />

We have developed an imaging system that is optimized for MV and can acquire <strong>Megavoltage</strong> CBCT<br />

images containing soft tissue contrast using a 6MV x-ray beam with irradiation in range of 3 to 16cGy.<br />

The main components of this system are a high quantum efficient flat panel detector, readout interface<br />

with linac, calibration/corrections process, image preprocessing with dose/resolution adaptive filter,<br />

and scatter corrections. It can resolve a contrast resolution of 1%, gold seeds of 1mm x 3mm (1mm in<br />

diameter and 3mm in length), and air structures of 2mm in diameter.<br />

Clinical MV CBCT images revealed that structures such as prostate and optical nerve are visible with<br />

irradiation of 3 to 8cGy. This system (using receptor 1) can also be used for routine portal imaging<br />

applications without risk of saturation for high dose/high energy treatment/verification imaging, or<br />

dosimetry applications. This system can also deliver good quality MV CBCT images with 1 cGy that<br />

opens the possibility of the use of this system for 4D-CT.<br />

REFERENCES<br />

1. H. Barrett, S. Gordon, and R. Hershel, Statistical limitations in transaxial tomography, Comput. Biol.<br />

Med. 6, 307-323, 1976.<br />

2. F. Ghelmansarai, P. Virador, M. Mitschke, A new dose and resolution adaptive filter, AAPM<br />

(American Association of Physicist in Medicine) 46 th Annual Meeting, 2004.<br />

3. R. Rajapakshe, K. Luchka, and S. Shalev, A quality control test for electronic portal imaging devices,<br />

Med. Phys. 23 (7) 1237-1244, 1996.

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