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Inhalation of Non-carcinogenic Contaminants Eq.18 where: mg/kg = THQ AT EF ED ET ( 1 ) [( RfC 1 1 ) or ( PEF VF )] THQ = Target hazard quotient of 1 AT = Averaging time (25 years x 365 days/year x 24 hours/day) EF = Exposure frequency (225 days/year) ED = Exposure duration (25 years) ET = Exposure time (8 hours/day) RfCi = Inhalation reference concentration in (chemical specific) (mg/m 3 ) PEF = Particulate emission factor used for dusts (1.2×10 9 m 3 /kg) VF = Volatilization factor used for volatile organic chemicals (m 3 /kg) Skin Contact with Carcinogenic Contaminants Eq. 19 where: mg/kg = TR BW AT 365 days/year EF ED 10 -6 kg/mg SA AF ABS TR = Target risk of 10 -6 BW = Body weight of adult (70 kg) AT = Averaging time of worker (25 years) EF = Exposure frequency (225 days/year) ED = Exposure duration of worker (25 years) SFo = Oral cancer slope factor (chemical specific) (mg/kg-day) -1 SA = Surface area exposed for adult (3300 cm 2 /day) AF = Adherence factor (0.2 mg/cm 2 ) ABS = Skin absorption (chemical specific) Skin Contact with Non-carcinogenic Contaminants Eq. 20 mg/kg = where: THQ = Target hazard quotient of 1 THQ BW AT 365 days/year EF ED 1 10 RfD -6 kg/mg SA AF ABS 17
BW = Body weight of adult (70 kg) AT = Averaging time of outdoor worker (25 years) EF = Exposure frequency (225 days/year) ED = Exposure duration of worker (25 years) RfDo = Oral reference dose (chemical specific) (mg/kg-day) SA = Surface area exposed for adult (3300 cm 2 /day) AF = Adherence factor (0.2 mg/cm 2 ) ABS = Skin absorption (chemical-specific) Soil BCL for Combined Exposure Pathways for Carcinogenic Contaminants for Outdoor Commercial/Industrial Worker Eq. 21 mg/kg = 1 . 15 + 1 1 . 17 + 1 . 19 Soil BCL for Combined Exposure Pathways for Non-carcinogenic Contaminants for Outdoor Commercial/Industrial Worker Eq.22 mg/kg = 3.4 Equations for Ambient Air 1 . 16 + Inhalation of Carcinogenic Contaminants Eq. 23 where: µg/m 3 ) = 1 1 . 18 + TR AT ET EF ED 1 . 20 TR = Target risk of 10 -6 AT = Averaging time (25 years x 365 days/year x 24 hours/day) ET = Exposure time (24 hours/day) EF = Exposure frequency (350 days/year) ED = Exposure duration of adult resident (30 years) IURi = Inhalation unit risk (chemical specific) (μg/m 3 ) -1 18
Page 1 and 2: USER’S GUIDE AND BACKGROUND TECHN
Page 3 and 4: DISCLAIMER The Nevada Division of E
Page 5 and 6: 3.7 for addressing multiple chemica
Page 7 and 8: Environmental Media Soil Ingestion
Page 9 and 10: quotients should be calculated usin
Page 11 and 12: Default values for the soil “sat
Page 13 and 14: 3.0 HUMAN HEALTH-BASED BCLs A multi
Page 15 and 16: Skin Contact of Carcinogenic Contam
Page 17 and 18: ED = Exposure duration (25 years) I
Page 19: Ingestion of Non-carcinogenic Conta
Page 23 and 24: where: THQ = Target hazard quotient
Page 25 and 26: For cancer risk estimates, divide t
Page 27 and 28: http://www.epa.gov/superfund/health
Page 29 and 30: enzo(a)pyrene (1.0), benzo(a)anthra
Page 31 and 32: LBCLs were calculated for the 15 in
Page 33 and 34: concentrations is expected at a sit
Page 35 and 36: National Toxicology Program (NTP),
Page 37 and 38: USEPA. 2002a. Supplemental Guidance
Page 39 and 40: USEPA. 2000. Supplementary Guidance
Page 41 and 42: February 2009 1. Corrections to Equ
Page 43 and 44: May, 2012 1. Leaching LBCL added fo
Page 45 and 46: TABLE B‐1 TOXICOLOGICAL SURROGATE
Page 47 and 48: Table B‐2. Surrogate Inhalation T
Page 49 and 50: Table C‐1 Source of “Other” T
Page 51 and 52: Table D-1. DRAFT Leaching Based Bas
Page 53 and 54: Appendix E USER’S GUIDE FOR NEVAD
Page 55 and 56: 1.0 BACKGROUND This guidance, which
Page 57 and 58: Environmental Media Soil Soil (Grou
Page 59 and 60: The dilution attenuation factor (DA
Page 61 and 62: 3.1 Residential Scenario BCL Equati
Page 63 and 64: 3.2 Industrial / Commercial Scenari
Page 65 and 66: Table E-2. Behavioral and Receptor
Page 67 and 68: As described in Section 1.1, inhala
Page 69: USEPA. 1999. Cancer Risk Coefficien

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