Magnetic Separation: Industrial and Lab Scale Applications

More documents

Recommendations

Info

Figure 15. A magnetic device for separation of red blood cells. (from ref [Haik 1999 JMMM]) d. Drug Delivery
Bio-distribution of pharmaceuticals always faces a big challenge: Unspecific, evenly distribution of the drugs all over the body. This requires a large amount of the dose to get enough of it to the target which also brings a side effect of the non-specific toxicity in healthy sectors. Among other drug targeting methods, magnetic targeting offers one of the most viable solutions to the targeting problem (Torchilin 2000 Europ J Pharm). To our knowledge, first applications in magnetic drug targeting date back to late 1970s (Mosbach 1979 <strong>and</strong> Senyei 1978, Widder 1978). For a successful delivery, a carrier must also be fully controllable. Aggregation, clogging or intrinsic, permanent magnetic behavior is completely unacceptable. Superparamagnetic iron oxides, therefore, offer both requirements for being an excellent shuttle for a successful drug delivery. Figure 12 explains how a magnetically targeted carrier would work.
Page 1 and 2: Magnetic Separation: Industrial and
Page 3 and 4: A. Value of Magnetic Separation Alt
Page 5 and 6: energy of the Brownian motion, henc
Page 7 and 8: words with a high gradient magnetic
Page 9 and 10: Figure 2. Metso® High Gradient Mag
Page 11 and 12: diameter magnetic filter removes 80
Page 13 and 14: separation. The magnetic nature of
Page 15 and 16: Figure 7. An industrial scale drum
Page 17 and 18: window and safety switches. The hig
Page 19 and 20: A summary of key requirements for a
Page 21 and 22: magnetic polymer latexes for isolat
Page 24 and 25: Figure 13. Examples of batch magnet
Page 26 and 27: Labeled cells, i.e. neural progenit
Page 30 and 31: Figure 16. Magnetic Targeted Carrie
Page 32 and 33: (Gao 2003 ChemComm) and peroxidase
Page 34 and 35: i. N.J. Saikia, D.J. Bharali, P. Se
Page 36 and 37: 12. Dailey J P, Phillips J P, Li C

Magnetic Separation: Industrial and Lab Scale Applications

Create successful ePaper yourself

Delete template?

Save as template?