Magnetic Separation: Industrial and Lab Scale Applications

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pressurised heated water-jacket maintains the temperature of the chocolate. All 316 stainless steel, and manufactured to food industry standards. e. Arsenic removal – Water treatment (JT) [in progress] D. Biotechnological (Batch) Applications The ability to control remotely inspired many biotechnologists and medical scientists to investigate magnetic solutions for several biochemical processes, such as protein and cell separations and purifications, magnetic drug targeting and delivery, and enzyme based bio-catalysis. Unlike industrial applications, in-lab or batch applications require tailor- made magnetic materials but remain fine with steady, not continuous, bench-top or batch, process solutions. First, we will give key components of a magnetic material to be used in vivo and then review some of the biological applications of magnetic separation. a. Materials requirement In vivo applications of magnetic materials require biocompatibility. Thus, biochemists tend to use naturally existing minerals, such as magnetic iron oxides (magnetite, Fe3O4 and maghemite, γ-Fe2O3), due to their biologically safe nature i.e. in the ferrofluids (Tartaj 2003 J of Phy).
A summary of key requirements for a bio-magnetic separation material is as follows (also depicted in Figure 8): 1. Biocompatibility 2. Suitable linkers 3. Functional layers on magnetic core 4. Protective layer 5. Antigen detection 6. Shape recognition 7. Fluorescent signaling
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Page 9 and 10: Figure 2. Metso® High Gradient Mag
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Page 15 and 16: Figure 7. An industrial scale drum
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Magnetic Separation: Industrial and Lab Scale Applications

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