Dr. Lyon's Curriculum Vitae - University of Utah - School of Medicine
Dr. Lyon's Curriculum Vitae - University of Utah - School of Medicine Dr. Lyon's Curriculum Vitae - University of Utah - School of Medicine
Personal Data Date of Birth 01/26/1974 Location of Birth Houston, Texas Citizenship USA 1 Curriculum Vitae Gholson J. Lyon 6017 Pioneer Fork Road Salt Lake City, UT 84108 Phone: 646-872-1219 Email: Gholson.Lyon@hsc.utah.edu Gholson J. Lyon, M.D., Ph.D. Education Year Degree Field Institution 1992-96 B.A. Biochemistry Dartmouth College 1996-97 M.Phil. Genetics Christ’s College, University of Cambridge, England 1999-2003 Ph.D. Chemical Biology Rockefeller University 1997-99 & 2003-04 M.D. Medicine Weill Cornell Medical College (Cornell/Rockefeller/Sloan-Kettering MD/PhD program) Postdoctoral Training Year Specialty Place of Training 2004-05 Internship in Medicine and Psychiatry Columbia Presbyterian Hospital 2005-07 Residency in Adult Psychiatry Columbia Presbyterian Hospital and New York State Psychiatric Institute 2007-09 Residency in Child and Adolescent NYU Child Study Center, Bellevue Hospital, and Psychiatry Rockland Children’s Hospital Licensure and Certification 2006- New York State License #237203-1 2009- Utah State License #7291583-1205 and -8905 2009- Board-certified, Psychiatry Diplomate of the American Board of Psychiatry and Neurology. Certificate #59700, April 2009 Academic Appointments 2007-2009 Clinical Instructor (part-time) in the Department of Child and Adolescent Psychiatry at NYU Child Study Center, New York City 2009-present Adjunct Assistant Professor, Department of Child and Adolescent Psychiatry at NYU Child Study Center, New York City July-Aug 2009 Clinical Instructor, Department of Psychiatry, University of Utah, Salt Lake City Sept 2009- Assistant Professor, tenure-track, Department of Psychiatry, University of Utah, Salt Lake City Hospital Appointments 2004-07 New York Presbyterian Hospital, Manhattan, house staff 2004-07 New York State Psychiatric Institute, Manhattan, house staff 2006-07 Moonlighting psychiatry attending at St. Joseph’s Hospital, Yonkers, NY 2006-09 Moonlighting psychiatry attending at Mt.Vernon Hospital, Mt.Vernon, NY 2007-08 Moonlighting psychiatry attending at NYU Tisch ER for NYU undergraduate students 2007-09 Bellevue Hospital, Manhattan, house staff 2007-09 Rockland Children’s Psychiatric Hospital, Rockland, NY, house staff 2009- University Neuropsychiatric Institute, University of Utah, attending psychiatrist.
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Personal Data<br />
Date <strong>of</strong> Birth 01/26/1974<br />
Location <strong>of</strong> Birth Houston, Texas<br />
Citizenship USA<br />
1<br />
<strong>Curriculum</strong> <strong>Vitae</strong><br />
Gholson J. Lyon<br />
6017 Pioneer Fork Road<br />
Salt Lake City, UT 84108<br />
Phone: 646-872-1219<br />
Email: Gholson.Lyon@hsc.utah.edu<br />
Gholson J. Lyon, M.D., Ph.D.<br />
Education<br />
Year Degree Field Institution<br />
1992-96 B.A. Biochemistry Dartmouth College<br />
1996-97 M.Phil. Genetics Christ’s College, <strong>University</strong> <strong>of</strong> Cambridge, England<br />
1999-2003 Ph.D. Chemical Biology Rockefeller <strong>University</strong><br />
1997-99 &<br />
2003-04 M.D. <strong>Medicine</strong> Weill Cornell Medical College<br />
(Cornell/Rockefeller/Sloan-Kettering MD/PhD program)<br />
Postdoctoral Training<br />
Year Specialty Place <strong>of</strong> Training<br />
2004-05 Internship in <strong>Medicine</strong> and Psychiatry Columbia Presbyterian Hospital<br />
2005-07 Residency in Adult Psychiatry Columbia Presbyterian Hospital and<br />
New York State Psychiatric Institute<br />
2007-09 Residency in Child and Adolescent NYU Child Study Center, Bellevue Hospital, and<br />
Psychiatry Rockland Children’s Hospital<br />
Licensure and Certification<br />
2006- New York State License #237203-1<br />
2009- <strong>Utah</strong> State License #7291583-1205 and -8905<br />
2009- Board-certified, Psychiatry Diplomate <strong>of</strong> the American Board <strong>of</strong> Psychiatry and Neurology. Certificate<br />
#59700, April 2009<br />
Academic Appointments<br />
2007-2009 Clinical Instructor (part-time) in the Department <strong>of</strong> Child and Adolescent Psychiatry at NYU<br />
Child Study Center, New York City<br />
2009-present Adjunct Assistant Pr<strong>of</strong>essor, Department <strong>of</strong> Child and Adolescent Psychiatry at NYU<br />
Child Study Center, New York City<br />
July-Aug 2009 Clinical Instructor, Department <strong>of</strong> Psychiatry, <strong>University</strong> <strong>of</strong> <strong>Utah</strong>, Salt Lake City<br />
Sept 2009- Assistant Pr<strong>of</strong>essor, tenure-track, Department <strong>of</strong> Psychiatry, <strong>University</strong> <strong>of</strong> <strong>Utah</strong>, Salt Lake City<br />
Hospital Appointments<br />
2004-07 New York Presbyterian Hospital, Manhattan, house staff<br />
2004-07 New York State Psychiatric Institute, Manhattan, house staff<br />
2006-07 Moonlighting psychiatry attending at St. Joseph’s Hospital, Yonkers, NY<br />
2006-09 Moonlighting psychiatry attending at Mt.Vernon Hospital, Mt.Vernon, NY<br />
2007-08 Moonlighting psychiatry attending at NYU Tisch ER for NYU undergraduate students<br />
2007-09 Bellevue Hospital, Manhattan, house staff<br />
2007-09 Rockland Children’s Psychiatric Hospital, Rockland, NY, house staff<br />
2009- <strong>University</strong> Neuropsychiatric Institute, <strong>University</strong> <strong>of</strong> <strong>Utah</strong>, attending psychiatrist.
2<br />
Gholson J. Lyon, M.D., Ph.D.<br />
Other Pr<strong>of</strong>essional Positions and Visiting Appointments<br />
2007-08 Moonlighting psychiatrist at NYC Administration for Children's Services<br />
2007-09 Private Practice, Psychiatry, 1036 Park Avenue, Suite 1B, New York, NY 10028<br />
Awards and Honors<br />
1990 Jenks Trojan Classic, Cross-examination Debate, 1 st place Speaker award<br />
1991-92 Third Place in cross-examination debate at Texas Forensic Association State Tournament<br />
1992 Trinity Tournament, 1 st place Speaker award, Cross-examination Debate<br />
1992 NFL National Qualifier, 62 nd National Debate Tournament, Fargo, North Dakota<br />
1991-92 Winston Churchill Debate, Outstanding Performance<br />
1991-92 Presidential Academic Fitness Award<br />
1991-92 National Merit Semi-Finalist<br />
1992 Terry Foundation Scholarship for attendance at <strong>University</strong> <strong>of</strong> Texas, Austin (declined)<br />
1993-96 Marshall O'Bell Scholarship by San Antonio Area Foundation for college education<br />
1993-94 World Affairs Scholarship for study at Dartmouth College<br />
1992-93 Dartmouth College Debate Team member<br />
1993 Rufus Choate Scholar, Dartmouth College<br />
1992-96 David T. Hedges Memorial Scholarship from Dartmouth College<br />
1995 Federation <strong>of</strong> German American Clubs Scholarship for one-year study in Germany (declined)<br />
1996 Phi Beta Kappa, summa cum laude<br />
1996 Dartmouth Department <strong>of</strong> Biology Christopher G. Reed Award for undergraduate senior thesis<br />
1996-97 Rotary International Ambassadorial Scholar, <strong>University</strong> <strong>of</strong> Cambridge<br />
1997-2004 NIH-sponsored Medical Scientist Training Program (MSTP) Award<br />
2003-04 Papanicolaou Medical Scientist Fellowship<br />
2007 AACAP Pilot Research Award for Attention Disorders for a Junior Faculty or Child Psychiatry Resident,<br />
supported by Elaine Schlosser Lewis Fund<br />
2007 Attendee, 1 st Annual AACAP Mentoring Institute in Chicago<br />
2008 Attendee, 7 th Annual Career Development Institute in Psychiatry, hosted in Pittsburgh<br />
2008 AACAP Outstanding Child and Adolescent Psychiatry Resident Award<br />
2009 APIRE/Wyeth Pharmaceuticals M.D./Ph.D. Research Award<br />
Committee Assignments or other duties<br />
2005-07 Columbia house staff-sponsored Grand Rounds selection committee<br />
2006-07 Columbia Presbyterian Hospital Emergency Room Task Force<br />
2007-08 Interviewer for residency applicants at NYU Child Study Center<br />
2009- Retention, Promotion, Tenure Committee, Dept. <strong>of</strong> Psychiatry, Univ. <strong>of</strong> <strong>Utah</strong>.<br />
Memberships, Offices, and Committee Assignments in Pr<strong>of</strong>essional Societies<br />
2000-2004 American Chemical Society (ACS)<br />
2000-2004 American Society for Microbiology (ASM)<br />
2004- American Association for the Advancement <strong>of</strong> Science (AAAS)<br />
2004- American Psychiatric Association (APA)<br />
2004- New York Academy <strong>of</strong> Sciences (NYAS)<br />
2007- American Academy <strong>of</strong> Child and Adolescent Psychiatry (AACAP), member #224997<br />
2007- American Neuropsychiatric Association (ANPA)<br />
2008- Collegium Internationale Neuro-Psychopharmacologicum (CINP), member #1129<br />
2008- Society for Neuroscience (SFN), member #100048491<br />
2009- American Society <strong>of</strong> Human Genetics (ASHG), member #101002<br />
Editorial Positions<br />
Peer reviewer: American Journal <strong>of</strong> Psychiatry, Journal <strong>of</strong> Clinical Psychiatry, Open Journal <strong>of</strong><br />
Neuropsychopharmacology, Journal <strong>of</strong> Clinical Psychopharmacology, Journal <strong>of</strong> Child and Adolescent<br />
Psychopharmacology.
Principal Clinical and Hospital Service Responsibilities<br />
2004-07 Columbia Presbyterian Hospital, resident<br />
2007-09 Bellevue Hospital, child fellow<br />
2009- <strong>University</strong> Neuropsychiatric Institute (UNI), <strong>University</strong> <strong>of</strong> <strong>Utah</strong><br />
Major Administrative Responsibilities<br />
2005-06 Scheduling liaison for Columbia PGY-2 class<br />
2007 Columbia CPEP emergency room resident liaison<br />
3<br />
Gholson J. Lyon, M.D., Ph.D.<br />
Teaching Experience<br />
Fall 1994 System Dynamics, Teaching Assistant, Dartmouth College, 10 hours/week<br />
Summer 1995 Molecular Biology, Teaching Assistant, Dartmouth College, 5 hours/week<br />
1999-2002 Medical school journal club tutor for Host Defenses, Genes and Development, and Molecules to Cells, 2<br />
hours/week<br />
2001-2003 Trained undergraduate students, graduate students and postdoctoral fellows in peptide chemistry, HPLC,<br />
mass spectrometry, molecular biology, protein expression/purification, native chemical ligation and<br />
bioassays, 10 hours/week<br />
Summer 2003 Gateways minority students program, leading undergraduate minority students through hospital<br />
experiences, 3 hours/week<br />
Fall 2005 Psychiatry interviewing class for medical students, 2 hours/week<br />
Spring 2006 Evidence-Based Psychiatry for medical students, 3 hours/week<br />
Spring 2007 Journal Club for third-year medical students, 2 hours/week<br />
Fall 2009 Lecture to adult and child psychiatry residents, Tourette Disorder, one hour.<br />
Mentoring <strong>of</strong> Graduate Students, Residents, Post-Doctoral Fellows in Research<br />
2006-2009 Supervision and mentoring <strong>of</strong> third and fourth year medical students on the inpatient child, adolescent,<br />
and adult psychiatry wards, and at the Columbia intensive outpatient program (IOP).<br />
2009-<br />
Teaching Awards Received<br />
None<br />
Undergraduates When<br />
Edwin Etchu Nyambi 2009-<br />
Whitney Fitts 2009-<br />
Katrina Swaringen 2009-<br />
Solongo Tuya 2009-<br />
Catherine Chinwe Olumba 2009-<br />
Graduate Students<br />
Lingyang Xing 2010-<br />
Postdoctoral Fellows<br />
Research Experience<br />
Summer 1994–Winter 1995 Dartmouth Medical <strong>School</strong>, Undergraduate research with <strong>Dr</strong>. Christopher Lowrey:<br />
characterized DNAase-I hypersensitivity loci in the locus control region (LCR) <strong>of</strong> the ßglobin<br />
gene cluster<br />
Fall 1994–Spring 1996 Undergraduate Senior Honors Thesis, Dartmouth<br />
Mentor: <strong>Dr</strong>. Donald St.Germain, cloned mouse type III deiodinase gene, encoding an<br />
enzyme regulating thyroid hormone levels
Gholson J. Lyon, M.D., Ph.D.<br />
Summer 1996 National Institutes <strong>of</strong> Health (NIH), Laboratory <strong>of</strong> Chemoprevention, Characterized<br />
TGF-ß/p21 double knockout mice in the laboratory <strong>of</strong> <strong>Dr</strong>s. Michael Sporn, Anita<br />
Roberts, and John Letterio<br />
Fall 1996-Summer 1997 M.Phil. in Genetics, <strong>University</strong> <strong>of</strong> Cambridge, Mentor: Nobel Laureate <strong>Dr</strong>. Martin Evans:<br />
1) characterized SPARC and SC1 single/double knockout mice, 2) extensive exposure to<br />
gene trap and knockout mice technology<br />
Summer 1997 Cornell Medical College, rotation in the laboratory <strong>of</strong> <strong>Dr</strong>. Carl Nathan, studying the<br />
effect <strong>of</strong> small-molecule tyrosine kinase inhibitors on the bactericidal activity <strong>of</strong> primary<br />
human neutrophils<br />
Spring 1998-Spring 1999 Memorial Sloan-Kettering Research Institute, rotation in the laboratory <strong>of</strong> <strong>Dr</strong>. Mike<br />
Rosen using 2D-NMR and expressed protein ligation (EPL) to characterize protein<br />
variants <strong>of</strong> the GTPase, Cdc42<br />
Summer 1999-Fall 2002 Ph.D. in Chemical Biology, Rockefeller <strong>University</strong>, Topic: chemical and biological<br />
analysis <strong>of</strong> virulence regulation in Staphylococcus aureus, Mentors: <strong>Dr</strong>s. Tom Muir,<br />
Richard Novick<br />
Summer 2005-Winter 2008 Collaboration with <strong>Dr</strong>s. Jeff Lieberman, Holly Moore, Jonathan Javitch, Dave Sulzer and<br />
Anissa Abi-Dargham on a review concerning presynaptic dopamine in schizophrenia<br />
Summer 2007-present Collaboration with <strong>Dr</strong>s. Barbara C<strong>of</strong>fey and Xavier Castellanos on a study analyzing<br />
response to stimulant medications in children with co-morbid ADHD and Tourette’s<br />
disorder<br />
Grants Received<br />
1) Agency Tourette Syndrome Association<br />
Title Genotype and Phenotype analysis in large extended pedigrees with Tourette’s syndrome and/or<br />
tics<br />
Grant Period July 2010 - July 2011<br />
Role Principal Investigator<br />
Amount $75,000 for first year, with a second year renewable<br />
2) Agency AACAP, 2007 Pilot Research Award for Attention Disorders for a Junior Faculty or Child Psychiatry<br />
Resident, supported by Elaine Schlosser Lewis Fund. (Presenting at AACAP October 2009)<br />
Title A PILOT STUDY FOR RESPONSE INHIBITION WITH AND WITHOUT<br />
DEXMETHYLPHENIDATE IN BEHAVIOR THERAPY INTERVENTION FOR TICS IN CHILDREN<br />
AND ADOLESCENTS WITH ATTENTION DEFICIT HYPERACTIVITY DISORDER AND<br />
TOURETTE’S DISORDER OR CHRONIC MOTOR/VOCAL TIC DISORDER<br />
Grant Period September 2007 - September 2009<br />
Role Principal Investigator<br />
Amount $9000<br />
3) Agency Tourette Syndrome Association<br />
Title RESPONSE INHIBITION WITH AND WITHOUT DEXMETHYLPHENIDATE IN BEHAVIOR<br />
THERAPY INTERVENTION FOR TICS IN CHILDREN AND ADOLESCENTS WITH ATTENTION<br />
DEFICIT HYPERACTIVITY DISORDER AND TOURETTE’S DISORDER OR CHRONIC<br />
MOTOR/VOCAL TIC DISORDER<br />
Grant Period July 2008 - July 2011 (with one year no-cost extension)<br />
Role Co-Investigator; PIs are Barbara C<strong>of</strong>fey, M.D., M.S., and Douglas Woods Ph.D., other co-investigator is<br />
Francisco Xavier Castellanos, M.D<br />
Amount $150,000<br />
4) Agency Tourette Syndrome Association<br />
Title Functional connectivity <strong>of</strong> Tourette Syndrome: A pilot study.<br />
Grant Period July 2008 - July 2010 (with one year no-cost extension)<br />
Role Co-Investigator; PI is Francisco Xavier Castellanos, M.D., and other co-investigators are Michael<br />
Miham, M.D., Ph.D., Barbara C<strong>of</strong>fey, M.D., M.S., and Bharat Biswal, Ph.D.<br />
4
Amount $75,000.<br />
5<br />
Gholson J. Lyon, M.D., Ph.D.<br />
5) Agency APIRE<br />
Title 2009 APIRE/Wyeth Pharmaceuticals M.D. / Ph.D. Research Fellowship<br />
Grant Period July 2009-July 2010<br />
Role Principal Investigator<br />
Amount $45,000<br />
Patents<br />
None<br />
Boards and Community Organizations<br />
None<br />
Military Service<br />
None<br />
Other<br />
Foreign Study at Gutenberg <strong>University</strong>, Mainz, Germany, Winter 1994 and Berlin Free <strong>University</strong>, Berlin, Germany,<br />
Winter 1995<br />
Hobbies include reading, growing orchids, collecting old books and art, and travel<br />
Bibliography<br />
Original Reports<br />
1) Hernandez, A., Park, J. P., Lyon, G. J., Mohandas, T. K., and St Germain, D.L. (1998). Localization <strong>of</strong> the type 3<br />
iodothyronine deiodinase (DIO3) gene to human chromosome 14q32 and mouse chromosome 12F1. Genomics 53(1):<br />
119-21.<br />
2) Gilmour, D. T., Lyon, G. J., Carlton, M. B., Sanes, J. R., Cunningham, J. M., Anderson, J. R., Hogan, B. L., Evans, M.<br />
J., and Colledge, W. H. (1998). Mice deficient for the secreted glycoprotein SPARC/osteonectin/BM40 develop normally<br />
but show severe age-onset cataract formation and disruption <strong>of</strong> the lens. Embo J 17(7): 1860-70.<br />
3) Hernandez, A., Lyon, G. J., Schneider, M. J., and St. Germain, D. L. (1999). Isolation and characterization <strong>of</strong> the<br />
mouse gene for the type 3 iodothyronine deiodinase. Endocrinology 140(1): 124-30.<br />
4) Fuortes, M., Melchior, M., Han, H., Lyon, G. J., and Nathan, C. (1999). Role <strong>of</strong> the tyrosine kinase pyk2 in the<br />
integrin-dependent activation <strong>of</strong> human neutrophils by TNF. J Clin Invest 104(3): 327-35.<br />
5) Jarraud, S., Lyon, G. J., Figueiredo, A. M., Lina, G., Vandenesch, F., Etienne, J., Muir, T. W., and Novick, R.P.,<br />
(2000) Exfoliatin-producing strains define a fourth agr specificity group in Staphylococcus aureus. J Bacteriol, 182(22):<br />
6517-22.<br />
6) Lyon, G.J., Mayville, P., Muir, T. W., and Novick, R. P. (2000), Rational design <strong>of</strong> a global inhibitor <strong>of</strong> the virulence<br />
response in Staphylococcus aureus, based in part on localization <strong>of</strong> the site <strong>of</strong> inhibition to the receptor-histidine kinase,<br />
AgrC. Proc Natl Acad Sci,. 97(24): 13330-5.<br />
7) Lyon, G.J., J. S. Wright, Christopoulous, A., Novick, R., and Muir, T.W. (2002). Reversible and specific extracellular<br />
antagonism <strong>of</strong> receptor-histidine kinase signaling. J Biol Chem 277(8): 6247-53.<br />
8) Lyon, G.J., J.S. Wright, Muir, T.W., and Novick, R. (2002). Key determinants <strong>of</strong> receptor activation in the agr<br />
autoinducing peptides <strong>of</strong> Staphylococcus aureus. Biochemistry, 41 (31): 10095-10104.
Gholson J. Lyon, M.D., Ph.D.<br />
9) Miller, J.S., Dudkin, V.Y., Lyon, G.J., Muir, T.W., and Danishefsky, S.J. (2003). Toward Homogeneous, Synthetic N-<br />
Linked Glycoproteins, Angewandte Chemie International Edition, 42(4): 431-434.<br />
10) Kalkum, M., Lyon, G.J., and Chait, B.T. (2003) Detection <strong>of</strong> Secreted Peptides using Hypothesis driven Multistage<br />
Mass Spectrometry, Proc Natl Acad Sci, 100(5): 2795-2800<br />
11) Wright J.S. 3rd, Lyon G.J., George E.A., Muir T.W., Novick R.P. (2004) Hydrophobic interactions drive ligandreceptor<br />
recognition for activation and inhibition <strong>of</strong> staphylococcal quorum sensing. Proc Natl Acad Sci, 101(46):16168-<br />
73.<br />
12) Lyon, G.J. Varenicline-induced paranoia and irritability in a patient with major depressive disorder, borderline<br />
personality disorder (stable), and methamphetamine abuse (in remission). J Clin Psychopharmacol. (2008 Dec);28(6):720-<br />
1.<br />
13) Lyon, G.J., C<strong>of</strong>fey, B., Silva, R. Post-traumatic stress disorder (PTSD) and Reactive Attachment Disorder: Outcome<br />
in an Adolescent. J Child Adolesc Psychopharmacol. (2008 Dec);18(6):641-646.<br />
14) Lyon, G.J., C<strong>of</strong>fey, B., Complex tics and complex management in a case <strong>of</strong> severe Tourette’s disorder in an<br />
adolescent. J Child Adolesc Psychopharmacol. 2009 Aug;19(4):469-74.<br />
15) Lyon G.J., Samar S., Jummani R, Hirsch S, Spirgel A, Goldman R, C<strong>of</strong>fey B.J., Aripiprazole in children<br />
and adolescents with Tourette’s Disorder: An open label safety and tolerability study. J Child Adolesc Psychopharmacol.<br />
2009 Dec;19(6):623-33.<br />
16) Lyon, G.J., C<strong>of</strong>fey, B., Castellanos, X.F., Woods, D., Conelea, C., Samar, S., Bauer, C., Brandt, B.C., Kemp, J.K.,<br />
Lipinski, C.M., Trujillo, M.R., Lawrence, Z.E.. Improving Tic-Related Response Inhibition: Comparing the Effects <strong>of</strong><br />
Dexmethylphenidate to No Medication in Children and Adolescents with ADHD and Chronic Tic Disorders. 2010<br />
(manuscript submitted).<br />
17) Elia, J., Glessner, J., Wang, K., Lyon, G.J.., Faraone, S., Hakonarson, H. et al. Genome Wide Copy Number<br />
Variation Study Associates Metabotropic Glutamate Receptor Genes with Attention Deficit Hyperactivity Disorder. 2010<br />
(manuscript submitted).<br />
Reviews, Essays, Books, Book Chapters, Book Reviews<br />
1) Lyon, G.J., and Muir, T.W. (2003) Chemical Signaling among Bacteria, and its inhibition. Chemistry and Biology,<br />
10(11): 1007-1025.<br />
2) Lyon, G.J., and Novick, R.P. (2004) Peptide signaling in Staphylococcus aureus and other Gram-positive bacteria.<br />
Peptides, 25(9):1389-403.<br />
3) Lyon, G.J. and Koplewicz, Harold S. Schizophrenia in childhood: Why we need much more research into early-onset<br />
psychosis. SCIENTIST : 22-25 Schizophrenia Suppl. (DEC 2007).<br />
4) Lyon, G.J. and C<strong>of</strong>fey, B., Book Review <strong>of</strong>: Treating Tourette Syndrome and Tic Disorders: A Guide for<br />
Practitioners. Douglas W. Woods, John .C. Piacentini, and John T. Walkup, 2007, First Edition, The Guilford Press, New<br />
York. xvi, 287 pages. Hard cover. J Child Adolesc Psychopharmacol. (2008 Aug);18(4):411-412.<br />
5) Lyon, G.J. and C<strong>of</strong>fey, B., Book Review <strong>of</strong>: Attention-Deficit Hyperactivity Disorder: A Handbook for Diagnosis and<br />
Treatment. Russell A. Barkley, 2006, Third Edition, The Guilford Press, New York. xii, 770 pages. Hard cover. Journal<br />
<strong>of</strong> Clinical Psychiatry, vol 69, no. 6, (June 2008), p. 1023.<br />
6) Lyon, G.J., Moore, H., Lieberman, J.A., Abi-Dargham, A., Javitch, J. and Sulzer, D., (2009). Presynaptic regulation <strong>of</strong><br />
dopamine transmission in schizophrenia. Schizophrenia Bulletin. 2009 Jun 12. [Epub ahead <strong>of</strong> print]<br />
6
7<br />
Gholson J. Lyon, M.D., Ph.D.<br />
7) Lyon, G.J., Shprecher, D., C<strong>of</strong>fey, B. and Kurlan, R., Tourette’s Disorder, Current Treatment Options in<br />
Neurology, 2010, (submitted).<br />
Theses<br />
1) Lyon, G.J., Undergraduate Senior Thesis in Molecular Biology, Dartmouth College, Hanover, NH: Isolation and<br />
Characterization <strong>of</strong> the Mouse Type III Deiodinase Gene. (1996).<br />
2) Lyon, G.J., M.Phil. Thesis in Genetics, <strong>University</strong> <strong>of</strong> Cambridge, England: The Functional Characterization <strong>of</strong><br />
SPARC and SC1 Single and Double Knockout Mice. (1997).<br />
3) Lyon, G.J., Ph.D. Thesis in Chemical Biology, Rockefeller <strong>University</strong>, New York: Targeting Receptor-Histidine<br />
Kinase Signaling in Staphylococcus aureus. (2002).<br />
Abstracts (past three years)<br />
1) Lyon, G.J., C<strong>of</strong>fey, B., Castellanos, X.F., Woods, D., (July 2008) “Improving tic-related response inhibition:<br />
Comparing the effects <strong>of</strong> dexmethylphenidate to placebo in children and adolescents with ADHD and chronic tic<br />
disorders”, International Journal <strong>of</strong> Neuropsychopharmacology, vol 11, supplement 1, p. 292. CINP meeting.<br />
2) C<strong>of</strong>fey BJ, Jummani R, Hirsch S, Lyon G.J., Spirgel A, Goldman R, Samar S (2008, October). Aripiprazole in children<br />
and adolescents with Tourette’s Disorder: An open label safety and tolerability study. Poster presented at the AACAP<br />
55th Annual Meeting, Chicago, IL.<br />
3) Lyon, G.J., C<strong>of</strong>fey, B., Castellanos, X.F., Woods, D., Conelea, C., Samar, S., Bauer, C., Brandt, B.C., Kemp, J.K.,<br />
Lipinski, C.M., Trujillo, M.R., Lawrence, Z.E.. Improving Tic-Related Response Inhibition: Comparing the Effects <strong>of</strong><br />
Dexmethylphenidate to No Medication in Children and Adolescents with ADHD and Chronic Tic Disorders. Poster<br />
presented at the AACAP 56th Annual Meeting, Honolulu, Hawaii.<br />
4) Genome-wide analysis <strong>of</strong> copy number variation in extended autism pedigrees. Robison R, Wang K, Hobbs M, Cannon<br />
D, Lyon G, Miller J, Tuya S, Matsunami N, Leppert M, Hakonarson H, Davis L, Cook E, Facelli J, McMahon W, Coon<br />
H. Towards Defining the Pathophysiology <strong>of</strong> Autistic Behavior, Sponsored by Simons Foundation, Organizers: Pat Levitt<br />
and Joseph Piven, April 11 - 15, 2010 • Snowbird Resort • Snowbird, <strong>Utah</strong>.<br />
Invited Talks and Conferences Attended<br />
February 2001 Columbia/Rockefeller Chemical Biology Seminar Series, invited talk.<br />
May 2001 Rockefeller <strong>University</strong> Tri-Lab Seminar Series, invited talk.<br />
June 2001 Bioorganic Chemistry Gordon Conference, Proctor, NH, poster.<br />
August 2001 MD/PhD annual retreat, Glen Cove, Long Island, NY, selected talk<br />
August 2001 Staphylococcal Diseases Gordon Conference, Bristol, RI, poster.<br />
October 2001 Rockefeller <strong>University</strong> Graduate <strong>School</strong> Annual Retreat, Montauk, Long Island, NY, selected<br />
talk.<br />
October 2001 Microbial Pathogenesis and Host Defense Conference, Cold Spring Harbor, NY, selected talk.<br />
October 2001 Microbial Pathogenesis Seminar Series, Skirball Institute, NYU, invited talk.<br />
February 2002 RU Pels Seminar, invited talk, “Rational Design <strong>of</strong> Global Inhibitors <strong>of</strong> Virulence in S. aureus”.<br />
May 2002 Yale Chemical Biology Symposium, poster.<br />
July 2002 Enzymology Gordon Research Conference, Kimball Union, NH, poster.<br />
October 2002 PhD thesis defense seminar: “Switching virulence on and <strong>of</strong>f in Staphylococcus aureus”,<br />
Rockefeller <strong>University</strong>. Thesis committee: Tom Sakmar, Christopher Walsh, John McKinney,<br />
Tom Muir, Richard Novick.<br />
May 2004 157 th American Psychiatric Association (APA), annual meeting, New York City, attendee<br />
January 2006 Columbia Psychiatry Department Grand Rounds: Neuropsychiatric Case Formulation: A case <strong>of</strong><br />
severe OCD. Presenters: <strong>Dr</strong>s. Gholson Lyon, Carolyn Rodriguez, Dan Rosell, Kristin Leight;<br />
Discussants: <strong>Dr</strong>s. David Shaffer, Blair Simpson, Gordon Frankle.<br />
April 2007 Columbia Research Track Resident seminar series, presentation.
Gholson J. Lyon, M.D., Ph.D.<br />
October 2007 54 th American Academy <strong>of</strong> Child and Adolescent Psychiatry (AACAP), annual meeting, Boston,<br />
MA, attendee.<br />
December 2007 8 th Annual Elaine Schlosser Lewis ADHD Research Update Luncheon, invited speaker<br />
December 2007 1 st AACAP mentoring research retreat, invited participant, poster and oral presentation<br />
December 2007 46 th American College <strong>of</strong> Neuropsychopharmacology (ACNP), annual meeting, Boca Raton,<br />
Florida, attendee invited by Tom Insel, director <strong>of</strong> NIMH.<br />
February 2008 2 nd Annual Chemical Neurobiology Meeting, Nature publishing and New York Academy <strong>of</strong><br />
Sciences, attendee.<br />
April 2008 7 th Annual Career Development Institute in Psychiatry, Co-sponsored by the <strong>University</strong> <strong>of</strong><br />
Pittsburgh and Stanford <strong>University</strong>, oral presentation.<br />
April 2008 Review course, Clinical Neurology for Psychiatrists, sponsored by Albert Einstein College <strong>of</strong><br />
<strong>Medicine</strong>, attendee.<br />
May 2008 63 rd Annual Society <strong>of</strong> Biological Psychiatry Convention, attendee<br />
July 2008 50 th Anniversary and XXVI Congress <strong>of</strong> the CINP (Collegium Internationale Neuro -<br />
Psychopharmacologicum), Munich, Germany, attendee and poster presentation.<br />
September 2008 The Genomics <strong>of</strong> Common Diseases, September 6-9, 2008, The Broad Institute <strong>of</strong> MIT and<br />
Harvard, Cambridge, MA, USA, attendee.<br />
October 2008 55 th American Academy <strong>of</strong> Child and Adolescent Psychiatry (AACAP), annual meeting, Chicago,<br />
IL, attendee sponsored by AACAP Educational Outreach Award.<br />
December 2008 47 th American College <strong>of</strong> Neuropsychopharmacology (ACNP), annual meeting, Scottsdale,<br />
Arizona, attendee sponsored by Career Development Institute.<br />
February 2009 NYU Child Study Center, NYU Child and Adolescent Psychiatry Grand Rounds presentation,<br />
invited speaker, February 20, 2009. Tic Suppression and Executive Function in children with<br />
ADHD and Tourette’s Disorder<br />
March 2009 The Tourette Syndrome International Consortium for Genetics (TSAICG) workshop on<br />
Genome Wide Association Studies (GWAS) replication effort, Bethesda, MD, attendee.<br />
June 2009 5th International Scientific Symposium on Tourette Syndrome, Tourette Syndrome<br />
Association, New York City, NY<br />
August 2009 Obsessive Compulsive Foundation, Annual meeting, Minneapolis, MN, attendee.<br />
September 2009 Deep Brain Stimulation for Obsessive Compulsive Disorder, Medtronic, Minneapolis,<br />
MN, attendee.<br />
October 2009 Seminar for Division <strong>of</strong> Medical Genetics, <strong>University</strong> <strong>of</strong> <strong>Utah</strong>, “Neuropsychiatric<br />
genetics. Phenotype first? Or Genotype first?”, invited speaker.<br />
October 2009 59 th Annual Meeting <strong>of</strong> the American Society <strong>of</strong> Human Genetics (ASHG), Honolulu,<br />
Hawaii, attendee.<br />
October 2009 56 th American Academy <strong>of</strong> Child and Adolescent Psychiatry (AACAP), annual meeting,<br />
Honolulu, Hawaii, Oral Presentation on “Genetics <strong>of</strong> Tourette in a Large Pedigree” in<br />
Symposium: Update on Tourette's Disorder: From Research to Practice, and poster presentation<br />
on “Improving Tic-Related Response Inhibition: Comparing the Effects <strong>of</strong> Dexmethylphenidate<br />
to No Medication in Children and Adolescents with ADHD and Chronic Tic Disorders”.<br />
December 2009 ADHD Molecular Genetics Consortium, Sanibel Resort, Florida, attendee.<br />
December 2009 Tourette Syndrome Association meeting on Deep Brain Stimulation, Miami, Florida, attendee.<br />
April 2010 Towards Defining the Pathophysiology <strong>of</strong> Autistic Behavior, Sponsored by Simons<br />
Foundation, Organizers: Pat Levitt and Joseph Piven, April 11 - 15, 2010 • Snowbird<br />
Resort • Snowbird, <strong>Utah</strong><br />
8