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GLOBAL<br />

MARKETING<br />

RESEARCH<br />

PHOTO: JUPITER IMAGES<br />

There’s more to conducting <strong>marketing</strong> <strong>research</strong> overseas than translating<br />

survey questions and hiring local moderators to do interviews. Bart Weiner and<br />

Brian Hull offer a guide to getting it right in the world’s biggest markets<br />

One of the biggest developments in the pharmaceutical industry in<br />

recent years has been the evolution and growth of markets<br />

outside of the US. In just the past six years, the revenue attributed<br />

to overseas markets has grown from 35% to 45% of total pharma industry<br />

revenues. With this growth has come the need for marketers to<br />

understand the top foreign markets with the same depth and clarity with<br />

which they understand the US market.<br />

Many issues that were once only local to the US are now viewed<br />

broadly across the major markets throughout the world. To formulate<br />

their strategies and tactics, <strong>marketing</strong> teams must now answer a more<br />

complex set of questions:<br />

What is the future need for our product in various countries? What<br />

are the important clinical endpoints for our product on a <strong>global</strong> scale<br />

and within specific countries of interest? What segmentation strategies<br />

JUNE 2007 MM&M 55


PHOTO: JUPITER IMAGES<br />

General Tips for Conducting International<br />

Marketing Research<br />

Time is relative and people in different<br />

countries and cultures drum to their<br />

own beat. If you try to change<br />

people’s ingrained behavior, you<br />

will only feel frustrated. For example,<br />

Americans like the expression “time is<br />

money” and prefer to get down to business<br />

at a moment’s notice. Professionals in other<br />

countries prefer to get to know each other<br />

first and gain a feeling of trust prior to<br />

conducting business.<br />

Here are some general tips to consider:<br />

■ Remind yourself of the need to be patient, flexible<br />

and adaptable<br />

• “As soon as possible” does not have universal meaning<br />

■ Develop partnerships<br />

• Good local qualitative moderators are hard to find<br />

• Never underestimate the value of a quality <strong>research</strong> facility<br />

■ Have a backup plan for everything<br />

• Internet access is unpredictable (plan to use your personal<br />

e-mail account)<br />

• Bring extra versions of stimuli<br />

■ Expect travel delays and manage jet lag<br />

• Get to the first country a day early to adjust your sleep patterns<br />

• Beware of labor strikes (airlines, taxis, buses and trains can<br />

come to a halt)<br />

• Have 24-hour access to a travel agent or contact<br />

■ Always ask for directions from someone at the hotel<br />

or facility<br />

• Street names and building numbers can be very difficult to find<br />

■ Hotel chains are not created equal from country to<br />

country, so always ask colleagues for hotel<br />

recommendations<br />

■ Simultaneous interpreters can be inconsistent<br />

• Ask for moderators and interpreters who frequently<br />

work together<br />

■ Look up the names of relevant pharmaceutical products<br />

for each country<br />

• Brand names frequently vary by country—generic names are<br />

often the safest way to refer to a drug<br />

■ Back-room management is critical<br />

• Client teams get larger with the addition of local affiliates<br />

• Different <strong>research</strong> priorities by country can sidetrack the <strong>research</strong><br />

■ Be aware of local holidays<br />

• Always check local calendars when scheduling <strong>research</strong><br />

GLOBAL MARKETING RESEARCH<br />

should we employ on a <strong>global</strong> level and within specific countries to optimize<br />

our targeting efforts? What strategies should we employ in various<br />

countries to maximize access to our product around the world?<br />

What should be the <strong>global</strong> positioning and messaging strategies? What<br />

country-specific refinements need to be incorporated? How is the<br />

product performing in each country, e.g., tracking, and what local-level<br />

adjustments need to be considered?<br />

In order to support this increased need for information, savvy <strong>marketing</strong><br />

<strong>research</strong> agencies have broadened their offerings to ensure that<br />

the quality of information for <strong>marketing</strong> decisions is consistently high<br />

across the world.<br />

When product teams contemplate conducting <strong>marketing</strong> <strong>research</strong> in<br />

multiple countries, there are some key issues they should know before<br />

initiating the project. Even more critical, they should be confident that<br />

the <strong>marketing</strong> <strong>research</strong> agency or partner they choose to hire for each<br />

and every international project helps them refresh their knowledge<br />

about a number of key issues. This includes understanding:<br />

■Medical and reimbursement systems: Provides the context for understanding<br />

the level of access physicians and patients have to medications,<br />

as well as how much influence the system has on the choices made by<br />

prescribers<br />

■Treatment practices: Ensures that the right respondents are recruited<br />

in each region<br />

■ How and at what pace the project-related logistics and tasks get accomplished<br />

in each country:Allows for the management of expectations<br />

for what can be collected in each country and within what time frame.<br />

Just like well-prepared world travelers use guides that offer advice<br />

on what sites to visit, which hotels to consider and how to take advantage<br />

of the local cuisine, pharmaceutical <strong>marketing</strong> <strong>research</strong>ers need a<br />

master guide of practical tips for effectively executing insightful, yet<br />

inherently complicated, international studies.<br />

The balance of this article shares some general knowledge, tips and<br />

“best practices” for <strong>global</strong> <strong>marketing</strong> <strong>research</strong>. Keep the list handy to<br />

remind yourself of its contents prior to every international study. We<br />

provide focus on the top nine countries in terms of pharmaceutical<br />

revenues: the United Kingdom, France, Germany, Italy, Spain, Japan,<br />

Mexico, US and Brazil.<br />

United Kingdom<br />

When conducting medical <strong>marketing</strong> <strong>research</strong> in the UK, it is<br />

important to account for how the National Health Service (NHS)<br />

greatly influences the system, resulting in a very cost-conscious<br />

environment.<br />

Medical and Reimbursement System<br />

■ The NHS (National Health Service) rules the day<br />

• Most patients have government-sponsored insurance<br />

• Being cost conscious dominates in a mostly public healthcare system<br />

JUNE 2007 MM&M 57


• Physicians do not have much choice in trying to use expensive<br />

medications when the NHS will not pay for them<br />

• Generic alternatives are frequently used first line<br />

■ A minority of patients have private insurance that gives them<br />

access to a greater number of medications<br />

■ Direct-to-consumer promotion is prohibited<br />

Treatment Practices<br />

■ All specialist physicians working as part of the NHS are<br />

hospital-based<br />

■ Internal Medicine physicians (IMs) do not exist<br />

■ The dual Hematology/Oncology specialty does not exist<br />

• Generally speaking,Oncologists treat solid tumors and<br />

Hematologists treat liquid tumors<br />

• Clinical Oncology specialty combines radiation and<br />

medical oncology<br />

■ Consultants and Specialist Registrars (SPRs) should be<br />

considered for interviews<br />

• SPRs are “junior”physicians with less clinical experience,<br />

but still make decisions<br />

• Consultants manage multiple SPRs<br />

■ NICE (National Institutes for Clinical Excellence) guidelines<br />

greatly influence treatment decisions as they may influence funding<br />

decisions for medications<br />

■ Physicians tend to be relatively conservative in their treatment<br />

strategies and slower to adopt new therapies<br />

Logistical Tips<br />

■ London is a “must”city, but regional guidelines for specialty<br />

areas, e.g., oncology, may necessitate the addition of other cities<br />

such as Birmingham and Manchester<br />

■ Morning <strong>research</strong> is virtually impossible<br />

• Research can be conducted Monday through Friday<br />

• Workloads in the hospital allow for a few afternoon interviews,but<br />

evening time slots are preferable<br />

• One-hour qualitative telephone interviews are possible<br />

■ British English is not the same as US English<br />

• English-version materials should be reviewed and adjusted<br />

accordingly to account for British terminology<br />

France<br />

Conducting medical <strong>marketing</strong> <strong>research</strong> in France is relatively<br />

easier than in other countries as participants are generally cooperative,<br />

physicians’ prescribing choices are less regulated and there<br />

are fewer limits placed on scheduling interviews.<br />

Medical and Reimbursement System<br />

■ Most patients have state health insurance<br />

• Most drugs are included in the social security plan and reimbursed<br />

■ Payers are difficult to interview and not worth the cost<br />

• They refuse to answer a lot of questions due to confidentiality issues<br />

GLOBAL MARKETING RESEARCH<br />

• Interviewing Key Opinion Leaders (KOLs) about payer issues<br />

is often a better option<br />

Treatment Practices<br />

■ Regional hospitals tend to specialize in treatment areas, e.g.,<br />

leukemia versus lymphoma<br />

• Recruiting multiple physicians from the same hospital is<br />

necessary<br />

• Budget issues vary dramatically from hospital to hospital<br />

■ The dual Hematology/Oncology specialty does not exist<br />

■ Sampling of drugs is illegal<br />

Logistical Tips<br />

■ Research locations to consider include Paris, Lyon and Marseille<br />

■ There is a fair amount of flexibility for conducting <strong>research</strong><br />

• Morning,afternoon and evening interviews are possible<br />

• On-time and show rates are very good<br />

• 45- to 60-minute interviews are acceptable<br />

• Scheduling up to eight studio interviews per day is possible<br />

• Two to three focus groups per day is possible<br />

■ Avoidance of mixing specialties in focus groups is of even greater<br />

importance in France than in other countries<br />

■ Telephone-depth interviews are becoming more popular<br />

■ Average age of physicians is about 50 years old, so allow for at least<br />

30 years in practice for screeners<br />

■ Physicians generally have a distaste for projective techniques and<br />

“emotional response”methodologies<br />

■ Patient <strong>research</strong> can be interesting, but of minimal value because<br />

they generally indicate that physicians entirely influence the final<br />

decisions<br />

Germany<br />

Germany, it is important to remember that physicians are held<br />

accountable for their own budgets, which clearly affects their decision<br />

making. When conducting <strong>research</strong> in this country, Wednesday<br />

is the most productive day of the week.<br />

Medical and Reimbursement System<br />

■ Budget issues are critical among physicians<br />

• Healthcare system is mostly public<br />

• Monthly cost for prescription drugs per patient is assigned to<br />

physicians by the federal statutory health insurance or accredited<br />

association<br />

• If over budget,physicians need to defend themselves and be held<br />

accountable<br />

• Specialists generally get a larger budget than General Practitioners<br />

■ Hospitals are increasingly being funded based on Diagnostic<br />

Related Groups (DRGs)<br />

• This system results in partial restrictions on products and earlier<br />

hospital discharges<br />

■ Direct-to-consumer promotion is prohibited<br />

JUNE 2007 MM&M 59


Treatment Practices<br />

■ Regional differences can be important due to local protocol,<br />

especially in specialized treatment areas, e.g., HIV, oncology,<br />

hepatitis<br />

■ Many specialists are both hospital-based and office-based, e.g.,<br />

Oncologists, Hematologists, Urologists, Gastroenterologists, etc.<br />

■ Internal Medicine physicians (IMs) exist and are hospital-based<br />

specialists<br />

■ Hematologist/Oncologist is one dual specialty<br />

• No separate specialties for hematology and oncology<br />

Logistical Tips<br />

■ Research locations to consider include Berlin, Munich, Hamburg<br />

and Frankfurt<br />

■ Wednesdays are desirable for <strong>research</strong> due to availability<br />

• Wednesdays are reserved for <strong>research</strong>/administration or “days off”<br />

• Scheduling <strong>research</strong> on Monday and Friday can be difficult<br />

• Morning interviews are very difficult (start at noon)<br />

• German physicians are punctual,and on-time and show rates are<br />

excellent<br />

• 45- to 60-minute interviews are acceptable<br />

• Six to eight studio interviews per day is possible<br />

• Summer <strong>research</strong> is easier than in other EU countries<br />

■ Physicians generally have a distaste for projective techniques and<br />

“emotional response”methodologies<br />

• Responses tend to be literal<br />

■ Recruiting pharmacists is increasingly difficult as pharmacies<br />

become more centralized<br />

• Fewer pharmacists<br />

■ Patient empowerment is leading to increased <strong>research</strong> among<br />

consumers, but keeping the interview length short (20 to 25 minutes)<br />

is important<br />

Italy<br />

In Italy, citizens generally have open access to services and pharmaceuticals,<br />

but it is important to note that numerous regions, as<br />

well as different hospitals within them, create their own formulary.<br />

Medical and Reimbursement System<br />

■ Public access to healthcare is granted to every citizen<br />

• Most hospitals are public and open to everyone,with most services<br />

free or for a small fee<br />

• The wait for public services can be long and patients can pay for<br />

faster service,but it is expensive<br />

• Private insurance is becoming more popular<br />

■ General Practitioners (GPs) are warned by local healthcare<br />

authorities when they prescribe too many expensive agents<br />

• Physicians not held to a budget,but the government is expected to<br />

employ budgets<br />

■ The European Medicines Agency (EMEA) approves new drugs<br />

for use in Italy<br />

GLOBAL MARKETING RESEARCH<br />

• 20 regions create their own formulary and each hospital in<br />

each region creates its own formulary<br />

■ Prescription drugs are divided into many classes for reimbursement<br />

purposes when obtained at retail pharmacies<br />

• Class A—fully reimbursed<br />

• Class C—out-of-pocket<br />

Treatment Practices<br />

■ Regional differences can be important, especially in specialized<br />

treatment areas<br />

■ Specialists are typically hospital employees<br />

• Most have a public and private practice<br />

■ Oncologists treat solid tumors and Hematologists treat liquid tumors<br />

Logistical Tips<br />

■ Research locations to consider include Rome, Milan and Naples<br />

■ In-person interviews are much preferred over telephone interviews<br />

• Scheduling up to eight studio interviews per day is possible<br />

• Morning interviews are very difficult (start at 1 p.m.) as are Fridays<br />

• 60-minute in-person interviews are acceptable,but telephone inter<br />

views should not exceed 15 minutes<br />

• Internet surveys can take one to two weeks longer to field than in<br />

other countries<br />

• Physicians are routinely late, but do not mind waiting if asked<br />

■ Research participants tend to skew responses toward the higher end<br />

of scales as they do not want to appear negative<br />

Spain<br />

In Spain, behavioral and cultural differences by region are important<br />

to consider, motivating <strong>research</strong>ers to ensure sample coverage<br />

in Madrid and Barcelona at a minimum.<br />

Medical and Reimbursement System<br />

■ Most patients have state health insurance<br />

■ The central government approves the commercialization of<br />

pharmaceuticals, but regional governments can apply their own<br />

restrictions<br />

• Pricing and reimbursement strategies are decided on a national<br />

level,and Key Opinion Leaders (KOLs) are consulted<br />

• Clinical guidelines are important for reimbursement purposes<br />

■ Hospital pharmacists assume the role of gatekeepers for access<br />

to drugs<br />

■ Primary Care Physicians (PCPs) get economic bonuses if at least a<br />

minimum proportion of their prescriptions are for generic agents<br />

Treatment Practices<br />

■ Regional differences are important in highly specialized treatment<br />

areas, e.g., acute leukemia, HIV<br />

■ Most physicians are both office-based and hospital-based<br />

• Many work in the hospital in the morning and in a private practice<br />

in the afternoon<br />

JUNE 2007 MM&M 61


■ Internal Medicine physicians (IMs) do exist, but they tend to<br />

specialize in an area such as infectious disease, HIV, emergency care<br />

and intensive care<br />

■ Emergency room physicians do not exist as a specialty<br />

■ Hematologist/Oncologists exist<br />

• Hematologists treat liquid and solid tumors<br />

• Oncologists treat only solid tumors<br />

Logistical Tips<br />

■ Research participants take their time to commit—filling the schedule<br />

can take up to the day of <strong>research</strong><br />

• Scheduling up to eight studio interviews per day is possible<br />

• Morning interviews are virtually impossible (start at 1 p.m.)<br />

• Scheduling <strong>research</strong> on Fridays can be difficult<br />

• 45- to 60-minute in-person interviews are acceptable,but telephone<br />

interviews should not exceed 20 minutes<br />

• Internet surveys can take one to two weeks longer to field than in<br />

other countries<br />

■ Conducting <strong>research</strong> among seriously ill patients is considered<br />

unethical<br />

■ Privacy issues with patients can be a serious issue, e.g., HIV patients<br />

typically ensure they are not being videotaped<br />

Japan<br />

One can conduct excellent <strong>research</strong> in Japan and obtain extremely<br />

insightful results, but you must adapt your expectations about costs and<br />

timing. Research typically requires twice the time and money than any<br />

other country.<br />

Medical and Reimbursement System<br />

■ One national health insurance system where patients pay 30 percent<br />

of the total cost up to a maximum amount per year and then are fully<br />

covered<br />

• Those with severe chronic conditions or elderly are fully reimbursed<br />

■ A small amount of treatments are not reimbursed—“lifestyle<br />

treatments,”e.g., cosmetics, plastic surgeries, erectile dysfunction<br />

treatments, smoking cessation<br />

■ Hospital/clinics dispense prescription drugs either directly or<br />

through dispensing pharmacies as part of their infrastructure<br />

■ Off-label prescribing is much less common than in other countries<br />

Treatment Practices<br />

■ Two general treatment settings—hospitals (20-plus beds) and<br />

clinics (0-19 beds)<br />

■ Patients can choose their own doctor and treatment setting without<br />

cost differences<br />

■ Patients go to small clinics for relatively mild and short-term<br />

conditions and go to large hospitals for more severe diseases<br />

■ Generics are not widely acceptable—first, there are not enough<br />

incentives for generic prescribing, and second, questions of<br />

quality linger<br />

GLOBAL MARKETING RESEARCH<br />

■ All physicians are trained to be “specialists”—there are Internal<br />

Medicine physicians (considered specialists), but no General<br />

Practitioners<br />

■ Cancer is generally treated by the “body part”specialist, e.g.<br />

Gastroenterologists treat stomach cancer, Urologists treat prostate<br />

cancer, Breast Surgeons treat breast cancer<br />

Logistical Tips<br />

■ Doctors are considered key authority figures and addressed with<br />

reverence, on par with lawyers and politicians—as a result, it is often<br />

difficult for moderators to probe or challenge respondents on their<br />

ideas, and answers must often be obtained through indirect<br />

questioning<br />

■ Acceptable times for conducting in-studio interviews with physicians<br />

is limited to weekday evenings and occasionally Saturdays<br />

■ For quantitative <strong>research</strong> with physicians, the best approach is to<br />

have local field interviewers visit physician offices and fill out the<br />

questionnaire on paper<br />

■ A typical 45-minute interview will take 60 to 75 minutes in Japan<br />

■ Focus group sizes are generally small—typically made up of six<br />

respondents who are similar demographically, e.g., ages, position, etc.<br />

■ Phone interviews must be short (five minutes or less) since it is<br />

culturally more appropriate to talk in person<br />

■ Videotaping respondents typically does not happen because of<br />

privacy laws<br />

Mexico<br />

Medical <strong>marketing</strong> <strong>research</strong> is not conducted as often in Mexico as it is<br />

elsewhere, but a recent increase in requests to consider it for a greater<br />

number of <strong>research</strong> studies suggests that could change.<br />

Medical and Reimbursement System<br />

■ There are two main healthcare systems:<br />

• IMSS (Instituto Mexicano del Seguro Social)—attends to private<br />

company workers<br />

• ISSSTE (Instituto de Seguridad y Servicios Sociales de los<br />

Trabajadores del Estado)—attends to government workers<br />

• Drugs are generally dispensed to those patients at no cost<br />

(some hospitals require a minimum payment)<br />

■ Private patients (non-IMSS and non-ISSSTE) pay out-of-pocket<br />

for their medications, and deductibles can be more expensive than<br />

the cost of the medication<br />

■ To sell more medications, pharmacies may not ask to see an actual<br />

prescription when dispensing, but they do require seeing<br />

prescriptions for restricted drugs, e.g., opioids<br />

Logistical Tips<br />

■ Extra personal attention is required during recruiting efforts,<br />

e.g., recruiters need to treat physicians as very important people<br />

■ Over-recruiting is necessary as physicians often cancel at the<br />

last minute<br />

JUNE 2007 MM&M 63


■ Physicians tend to require more time to complete surveys and<br />

interviews than in other countries<br />

• A 45-minute survey may take 55 to 60 minutes<br />

• Morning interviews are possible<br />

• Recruiting/scheduling up to eight respondents in one day is possible<br />

• Physicians are slowly adopting the practice of completing Internet<br />

surveys;they would rather speak to a moderator than sit in front of a<br />

computer<br />

■ Asking income questions is unacceptable<br />

• Surrogate questions are asked,e.g.,type of car owned,number of<br />

rooms in house,level of education for the head of the household<br />

■ Physicians tend to skew their ratings toward the higher end of the<br />

scale, e.g., they are very receptive to new products<br />

Brazil<br />

In Brazil, although participants are slower than their counterparts in<br />

other countries to adopt the practice of completing Internet-based<br />

surveys, they are still very willing and eager to take part in studies.<br />

Medical and Reimbursement System<br />

■ The Agencia Nacional de Vigilancia Sanitaria (ANVISA) is the<br />

governing body for pharmaceuticals<br />

■ There is no reimbursement for medication<br />

• Patients do not require a prescription,except for a few “controlled”<br />

medications<br />

Treatment Practices<br />

■ Physicians frequently work across multiple settings, e.g., hospitals,<br />

clinics, offices<br />

■ Many physicians prescribe “compounding”medications and<br />

refer to them as “formula”<br />

• Cheaper than generics and therefore more affordable<br />

• Problem:Patients do not know if the dosage of the medication is<br />

exactly as it is supposed to be<br />

Logistical Tips<br />

■ Physicians are open and willing to participate in <strong>marketing</strong> <strong>research</strong><br />

• Respondents accept and answer all types of questions<br />

• Recruiting/interviewing up to eight studio interviews per day<br />

is possible<br />

• Early morning <strong>research</strong> is possible<br />

• Friday <strong>research</strong> is very difficult<br />

• July and December are difficult months for <strong>research</strong><br />

• Physicians are very slowly adopting the practice of completing<br />

surveys on the Internet,thus in-office interviews are done for<br />

quantitative surveys<br />

■ Asking income questions is unacceptable<br />

• Surrogate questions are asked in order to approximate respondent’s<br />

income,e.g.,number of bathrooms in house,types of appliances,level<br />

of education for the head of the household,whether they employ a<br />

maid,type of car owned,etc.<br />

GLOBAL MARKETING RESEARCH<br />

United States<br />

By way of comparison, the United States is arguably the easiest country<br />

in the world to conduct pharmaceutical <strong>marketing</strong> <strong>research</strong>. The<br />

culture is very conducive for all kinds of qualitative and quantitative<br />

studies. As such, when conducting primary <strong>research</strong> in multiple<br />

countries where you include the US, it is important to remember to<br />

manage (not lower) expectations for the other countries where timelines<br />

are longer.<br />

Logistical Tips<br />

■ Money can solve a host of problems, including recruiting issues<br />

and tight timelines<br />

■ Many good facilities exist in most markets across the country<br />

(convenient, experienced recruiters and facility managers, very<br />

customer-focused)<br />

■ Facilities are state-of-the-art and comfortable<br />

(excellent Internet access)<br />

■ Research is conducted faster and with more flexibility than in<br />

other countries<br />

• All data collection methods acceptable,e.g.,in-person,in-office,<br />

phone,Internet,etc.<br />

• Easier to recruit all types of physicians (Generalists,Specialists,<br />

Key Opinion Leaders)<br />

■ The greatest risk is over-<strong>research</strong>ing a finite population<br />

• Beware of recruiting “professional”respondents time after time,<br />

especially in the top markets<br />

■ Beware of regional differences<br />

• Some markets are much more concerned about cost as a result<br />

of different levels of managed care influence<br />

• Some markets can be more “academic”or more “aggressive”than<br />

are others<br />

Conclusion<br />

As primary <strong>marketing</strong> <strong>research</strong> professionals continue to span the<br />

globe conducting and managing international studies, living with the<br />

“When in Rome…”philosophy in mind will greatly increase the probability<br />

that the <strong>research</strong> will be successful. To effectively manage expectations<br />

among everyone, including senior management, <strong>research</strong><br />

professionals should spend time before each international project<br />

reminding themselves of the local medical systems, treatment practices,<br />

and how and at what pace things get accomplished in the particular<br />

countries of interest.<br />

It is critical to be flexible, listen to the locals and build partnerships.<br />

Additionally, while the technology exists to observe <strong>research</strong> in most<br />

countries via videoconferencing, there is no substitute for physically<br />

being there to observe and develop a rich understanding of the <strong>research</strong><br />

results. ■<br />

Bart Weiner is president of GfK V2 and Brian Hull is president<br />

of GfK Strategic Marketing. Both companies are pharmaceutical<br />

<strong>marketing</strong> <strong>research</strong> and consulting firms and part of the GfK US<br />

Healthcare Companies.<br />

JUNE 2007 MM&M 65

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