changes in protein profiles in bortezomib applied multiple myeloma ...
changes in protein profiles in bortezomib applied multiple myeloma ...
changes in protein profiles in bortezomib applied multiple myeloma ...
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82<br />
27<br />
Y5S<br />
Table 4.2. Results of Differential Prote<strong>in</strong>s Identified MALDI-TOF Mass Spectrometry (cont.)<br />
SIVA<br />
Apoptosis<br />
Regulatory Prote<strong>in</strong><br />
Siva<br />
28 S8C Unidentified<br />
29<br />
S9C<br />
PYDC1<br />
Pyr<strong>in</strong> doma<strong>in</strong>conta<strong>in</strong><strong>in</strong>g<br />
prote<strong>in</strong> 1<br />
PSB3<br />
Proteasome subunit<br />
beta type-3<br />
LY6K Lymphocyte<br />
antigen 6K<br />
30 S10C Unidentified<br />
31 M10Sc Unidentified<br />
32 M10Sb Unidentified<br />
33 M10Sa Unidentified<br />
34<br />
M9S<br />
RAB25<br />
(Ras-related prote<strong>in</strong><br />
Rab-25)<br />
MPKRSCPFADVAPLQLKVRVSQRELSRGVCAERYSQEVFEKTKRLLFLGAQAYLDH<br />
VWDEGCAVVHLPESPKPGPTGAPRAARGQMLIGPDGRLIRSLGQASEADPSGVA<br />
SIACSSCVRAVDGKAVCGQCERALCGQCVRTCWGCGSVACTLCGLVDCSDMYEKV<br />
LCTSCAMFET<br />
-<br />
MGTKREAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTDKLV<br />
ASYYEDYAAELVVAVLRDMRMLEEAARLQRAA<br />
MSIMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAG<br />
LATDVQTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIA<br />
GLDPKTFKPFICSLDLIGCPMVTDDFVVSGTCAEQMYGMCESLWEPNMDPDHLFETI<br />
SQAMLNAVDRDAVSGMGVIVHIIEKDKITTRTLKARMD<br />
MALLALLLVVALPRVWTDANLTARQRDPEDSQRTDEGDNRVWCHVCERENTFECQ<br />
NPRRCKWTEPYCVIAAVKIFPRFFMVAKQCSAGCAAMERPKPEEKRFLLEEPMPFFY<br />
LKCCKIRYCNLEGPPINSSVFKEYAGSMGESCGGLWLAILLLLASIAAGLSLS<br />
-<br />
-<br />
-<br />
-<br />
MGNGTEEDYNFVFKVVLIGESGVGKTNLLSRFTRNEFSHDSRTTIGVEFSTRTVMLG<br />
TAAVKAQIWDTAGLERYRAITSAYYRGAVGALLVFDLTKHQTYAVVERWLKELYD<br />
HAEATIVVMLVGNKSDLSQAREVPTEEARMFAENNGLLFLETSALDSTNVELAFETV<br />
LKEIFAKVSKQRQNSIRTNAITLGSAQAGQEPGPGEKRACCISL<br />
14%<br />
25<br />
18.6/7.86<br />
- - -<br />
17%<br />
12%<br />
10%<br />
25<br />
14<br />
3<br />
10.1/6.29<br />
22.9/6.14<br />
18.6/7.44<br />
- - -<br />
- - -<br />
- - -<br />
- - -<br />
4%<br />
1<br />
23.4/5.72<br />
cont. on next page<br />
82