changes in protein profiles in bortezomib applied multiple myeloma ...

LIST OF TABLES
Table Page
Table 1.1 Genetic Alterations in MM ............................................................................... 8
Table 1.2. Prevalance of Important Translocations in MM .............................................. 9
Table 1.3. Laboratory Tests and Procedures to Diagnose the MM ................................ 14
Table 1.4. Durie-Salmon Staging System in MM .......................................................... 17
Table 1.5. International Staging System in MM ............................................................. 18
Table 2.1. Characteristics of protein stains ..................................................................... 34
Table 2.2. Advantages and disadvantages of protein profiling techniques .................... 44
Table 3.1. Preparation of BSA Standards and Test Sample
for the Bradford Protein Assay ....................................................................... 54
Table 3.2. Dilution of Protein Sample ............................................................................ 54
Table 3.3. Required Protein Sample with Rehydration Buffer ....................................... 59
Table 3.4. Bradford results for protein samples .............................................................. 59
Table 3.5. Reconstituted sample values .......................................................................... 59
Table 3.6. PROTEAN IEF Cell Program ....................................................................... 61
Table 3.7. Time Coarse for MALDI-TOF Compatible Mass Spectrometry .................. 63
Table 4.1. Magnified Segments of Differentiated Protein Spots .................................... 72
Table 4.2. Results of Differential Proteins Identified MALDI-TOF-TOF
Mass Spectrometry ......................................................................................... 78
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