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The concurrent validity of the Global Assessment of Functioning (GAF)

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British Journal <strong>of</strong> Clinical Psychology (2002), 41, 417–422<br />

2002 <strong>The</strong> British Psychological Society<br />

Brief report<br />

<strong>The</strong> <strong>concurrent</strong> <strong>validity</strong> <strong>of</strong> <strong>the</strong> <strong>Global</strong> <strong>Assessment</strong><br />

<strong>of</strong> <strong>Functioning</strong> (<strong>GAF</strong>)<br />

Mike Startup*, Mike C. Jackson and Sue Bendix<br />

School <strong>of</strong> Psychology, University <strong>of</strong> Wales, Bangor, UK<br />

www.bps.org.uk<br />

Background. Few studies <strong>of</strong> <strong>the</strong> <strong>validity</strong> <strong>of</strong> <strong>the</strong> <strong>Global</strong> <strong>Assessment</strong> <strong>of</strong> <strong>Functioning</strong><br />

(<strong>GAF</strong>) have been published and none has shown how <strong>GAF</strong> ratings are associated with<br />

<strong>concurrent</strong> ratings <strong>of</strong> symptoms and social functioning. This article provides such data.<br />

Method. Patients suffering from schizophrenia were assessed at admission to hospital<br />

and at six- and 12-month follow-up, using <strong>the</strong> <strong>GAF</strong>, <strong>the</strong> Scale for <strong>the</strong> <strong>Assessment</strong> <strong>of</strong><br />

Positive Symptoms (SAPS), <strong>the</strong> Scale for <strong>the</strong> <strong>Assessment</strong> <strong>of</strong> Negative Symptoms<br />

(SANS) and <strong>the</strong> Social Behaviour Schedule.<br />

Results. <strong>GAF</strong> ratings were highly correlated with ratings <strong>of</strong> symptoms and social<br />

behaviour at both follow-ups but not at initial assessment, although <strong>the</strong> inter-rater<br />

reliabilities for <strong>the</strong> measures were good.<br />

Conclusions. <strong>The</strong> <strong>GAF</strong> can be rated reliably after minimal training. It provides a valid<br />

summary <strong>of</strong> symptoms and social functioning among schizophrenic patients provided<br />

<strong>the</strong>y are not assessed when suffering from acute psychotic episodes.<br />

<strong>The</strong> <strong>Global</strong> <strong>Assessment</strong> <strong>of</strong> <strong>Functioning</strong> (<strong>GAF</strong>), based on <strong>the</strong> widely used <strong>Global</strong><br />

<strong>Assessment</strong> Scale (Endicott, Spitzer, Fleiss, & Cohen, 1976), was included as axis V in<br />

<strong>the</strong> revised third edition <strong>of</strong> <strong>the</strong> Diagnostic and Statistical Manual (DSM-III–R; American<br />

Psychiatric Association, 1987) and has been retained with only minor revisions in DSM-<br />

IV. It is a single rating scale for evaluating a person’s ‘psychological, social and<br />

occupational functioning on a hypo<strong>the</strong>tical continuum <strong>of</strong> mental health-illness’ and<br />

ranges from 1, representing <strong>the</strong> hypo<strong>the</strong>tically sickest individual, to 100, representing<br />

<strong>the</strong> hypo<strong>the</strong>tically healthiest. <strong>The</strong> scale is divided into 10 equal parts and provides<br />

defining characteristics for each 10-point interval. <strong>The</strong> defining characteristics include<br />

both symptoms and social functioning.<br />

<strong>The</strong> Work Group on Multiaxial Issues (Goldman, Skodol, & Lave, 1992) considered<br />

* Requests for reprints should be addressed to Pr<strong>of</strong> Mike Startup, School <strong>of</strong> Behavioural Sciences, University <strong>of</strong> Newcastle,<br />

Callaghan, NSW 2308, Australia (e-mail: mike.startup@newcastle.edn.au).<br />

417


418 Mike Startup et al.<br />

that simplicity and unidimensionality were two major advantages <strong>of</strong> <strong>the</strong> <strong>GAF</strong>, and<br />

Skodol, Link, Shrout, and Horwath (1988) commended axis V for providing a summary<br />

<strong>of</strong> many aspects <strong>of</strong> functioning that is useful for comparing <strong>the</strong> severity <strong>of</strong> illness<br />

between groups <strong>of</strong> patients with different diagnoses and for measuring change over<br />

time. However, few studies <strong>of</strong> <strong>the</strong> <strong>validity</strong> <strong>of</strong> <strong>the</strong> <strong>GAF</strong> appear to have been completed<br />

and, crucially, <strong>the</strong>re appears to have been no research on <strong>the</strong> degree to which <strong>GAF</strong><br />

ratings are associated with <strong>concurrent</strong> ratings <strong>of</strong> symptoms and social functioning. A<br />

few studies have examined such associations for <strong>the</strong> closely related <strong>Global</strong> <strong>Assessment</strong><br />

Scale (GAS), but <strong>the</strong>y have come to inconsistent conclusions. For example, Endicott et<br />

al. (1976) were not dissatisfied with <strong>the</strong> modest zero-order correlations <strong>the</strong>y obtained<br />

between <strong>the</strong> GAS and independent ratings <strong>of</strong> signs, symptoms and overt behavioural<br />

disorganization, but Holcomb & Otto (1988) concluded on <strong>the</strong> basis <strong>of</strong> similar<br />

correlations with signs and symptoms that <strong>the</strong> GAS had ‘questionable <strong>concurrent</strong><br />

<strong>validity</strong>’ (p. 282). However, previous reports have not provided data on <strong>the</strong> reliabilities<br />

<strong>of</strong> <strong>the</strong> ratings <strong>the</strong>y correlated with <strong>the</strong> GAS, nor have <strong>the</strong>y shown multiple correlations<br />

between <strong>the</strong> ratings and <strong>the</strong> GAS. Thus, <strong>the</strong>ir results are difficult to evaluate since one<br />

would not expect high correlations with unreliable measures, nor would one expect<br />

high correlations between ratings <strong>of</strong> specific symptoms and a global scale if <strong>the</strong> latter<br />

was designed to summarize information about symptoms and social functioning in<br />

general.<br />

<strong>The</strong> aims <strong>of</strong> <strong>the</strong> present study were, first, to assess <strong>the</strong> zero-order, partial and<br />

multiple correlations between ratings <strong>of</strong> symptoms, social functioning and <strong>the</strong> <strong>GAF</strong>,<br />

taking into account <strong>the</strong> reliabilities <strong>of</strong> <strong>the</strong> measures; and second, to assess how <strong>the</strong>se<br />

associations change between admission to psychiatric hospital during psychotic<br />

episodes and follow-up at both 6 and 12 months.<br />

Method<br />

Participants were recruits to a controlled trial <strong>of</strong> cognitive <strong>the</strong>rapy. Consecutive<br />

admissions to three psychiatric hospitals were considered eligible for inclusion if <strong>the</strong>y<br />

were aged between 18 and 65, had received a clinical diagnosis <strong>of</strong> schizophrenia,<br />

schizophreniform or schizoaffective disorder, were suffering an acute psychotic<br />

episode, and if <strong>the</strong>re was no evidence <strong>of</strong> organic mental disorder. <strong>The</strong> 214 patients<br />

who were considered to be eligible were invited to participate when <strong>the</strong>ir psychiatrist<br />

declared <strong>the</strong>m to be capable <strong>of</strong> informed consent. Of <strong>the</strong>se patients, 84 declined <strong>the</strong><br />

invitation. Those who accepted were <strong>the</strong>n excluded if more than 28 days had passed<br />

since <strong>the</strong>y were admitted or if, during a baseline assessment, <strong>the</strong>ir diagnoses could not<br />

be confirmed according to DSM-IV criteria, <strong>the</strong>y had been dependent on alcohol or<br />

illicit drugs during <strong>the</strong> past year, or <strong>the</strong>ir IQs were below 80. In all, 66 patients were<br />

excluded according to <strong>the</strong>se criteria, leaving 64 for <strong>the</strong> present sample.<br />

At initial assessment and at both 6- and 12-month follow-up, patients were rated,<br />

following a structured interview, on <strong>the</strong> Scale for <strong>the</strong> <strong>Assessment</strong> <strong>of</strong> Positive Symptoms<br />

(SAPS: Andreasen, 1984) and <strong>the</strong> Scale for <strong>the</strong> <strong>Assessment</strong> <strong>of</strong> Negative Symptoms (SANS:<br />

Andreasen, 1989). Following a structured interview with a ‘best informant’, usually a<br />

qualified mental health pr<strong>of</strong>essional, <strong>the</strong> patients were rated by <strong>the</strong> interviewer on <strong>the</strong><br />

Social Behaviour Schedule (SBS: Wykes & Sturt, 1986). This schedule covers 20<br />

behaviour areas that have been found to describe <strong>the</strong> major difficulties experienced by<br />

patients with long-term impairments. At <strong>the</strong> end <strong>of</strong> this interview <strong>the</strong> patients were


ated by both interviewer and informant independently, blind to each o<strong>the</strong>r’s ratings,<br />

on <strong>the</strong> <strong>GAF</strong>. Only a brief guide to <strong>the</strong> <strong>GAF</strong> (5min maximum) was provided to informants<br />

before <strong>the</strong>y made <strong>the</strong>ir ratings. Ratings were based on ei<strong>the</strong>r symptoms or social<br />

functioning, whichever had been worse. All interviews referred to <strong>the</strong> preceding<br />

month.<br />

At 6- and 12-month follow-up, interviews could not be conducted with 16 and 19<br />

patients, respectively and informants were unable to provide information on eight and<br />

14 patients, respectively. Most <strong>of</strong> <strong>the</strong>se data are missing because <strong>the</strong> patients had<br />

moved out <strong>of</strong> <strong>the</strong> area or <strong>the</strong>y were refusing contact with services.<br />

In order to assess <strong>the</strong> reliabilities <strong>of</strong> <strong>the</strong> ratings, 12 interviews with patients were<br />

sampled at random at each assessment point, with <strong>the</strong> constraint that no patient was<br />

sampled more than once, and audio-recordings <strong>of</strong> <strong>the</strong>se interviews were rated on <strong>the</strong><br />

SANS and <strong>the</strong> SAPS while blind to <strong>the</strong> interviewer’s ratings. <strong>The</strong>se ratings were for <strong>the</strong><br />

global items <strong>of</strong> each subscale except for affective flattening and avolition. Since some <strong>of</strong><br />

<strong>the</strong> items <strong>of</strong> <strong>the</strong> latter subscales depend on observations <strong>of</strong> <strong>the</strong> patients’ behaviour<br />

during interview, which could not be made from audio-recordings, independent ratings<br />

<strong>of</strong> affective flattening were based on affective non-responsivity and lack <strong>of</strong> vocal<br />

inflections, and ratings <strong>of</strong> avolition were based on impersistence and physical anergia.<br />

Independent ratings <strong>of</strong> bizarre behaviour could not be made. Ten interviews with<br />

informants were also sampled under <strong>the</strong> same constraints at each assessment point and<br />

recordings <strong>of</strong> <strong>the</strong>se interviews were rated on <strong>the</strong> SBS while blind to <strong>the</strong> interviewer’s<br />

ratings. All <strong>of</strong> <strong>the</strong>se independent ratings were made by <strong>the</strong> first author.<br />

Results<br />

Validity <strong>of</strong> <strong>the</strong> <strong>GAF</strong><br />

Inter-rater reliabilities (Table 1), assessed as intraclass correlations for two raters, were<br />

computed for <strong>the</strong> <strong>GAF</strong>, <strong>the</strong> global items <strong>of</strong> <strong>the</strong> SANS and <strong>the</strong> SAPS, and for <strong>the</strong> three<br />

dimensions that emerged from a principal components analysis <strong>of</strong> <strong>the</strong> SANS and SAPS<br />

by Andreasen, Arndt, Alliger, Miller, and Flaum (1995): negative symptoms, psychotic<br />

symptoms and disorganization. Reliabilities were also computed for a summary measure<br />

and four subscales <strong>of</strong> <strong>the</strong> SBS. <strong>The</strong> ‘mild and severe behaviour’ (Wykes & Sturt, 1986)<br />

score summarizes problematic social behaviour by counting how many <strong>of</strong> <strong>the</strong> 20<br />

behaviours assessed by <strong>the</strong> scale receive ratings <strong>of</strong> at least 2 (indicating at least mildly<br />

problematic behaviour). <strong>The</strong> SBS subscales were derived from a principal components<br />

analysis <strong>of</strong> a large sample <strong>of</strong> patients with a diagnosis <strong>of</strong> schizophrenia (Harvey, Curson,<br />

Pantelis, Taylor, & Barnes, 1996). Based on this analysis, <strong>the</strong> subscale ‘thought<br />

disturbance’ is <strong>the</strong> average <strong>of</strong> ratings for <strong>the</strong> items ‘incoherence <strong>of</strong> speech’, ‘odd/<br />

inappropriate conversation’ and ‘poor attention span’; <strong>the</strong> subscale ‘social withdrawal’<br />

is <strong>the</strong> average for <strong>the</strong> items ‘little spontaneous communication’, ‘poor self-care’,<br />

‘slowness’ and ‘underactivity’; <strong>the</strong> subscale ‘depressed behaviour’ is <strong>the</strong> average for <strong>the</strong><br />

items ‘depression’ and ‘suicidal ideas/behaviour’; and <strong>the</strong> subscale ‘anti-social<br />

behaviour’ is <strong>the</strong> average for <strong>the</strong> items ‘hostility’, ‘socially unacceptable habits’ and<br />

‘destructive behaviour’. Inter-rater reliabilities were at least adequate, and were usually<br />

excellent, for nearly all <strong>of</strong> <strong>the</strong>se measures at <strong>the</strong> three assessments (see Table 1).<br />

Table 1 also shows <strong>the</strong> zero-order correlations between <strong>the</strong> measures and <strong>the</strong><br />

average <strong>of</strong> <strong>the</strong> <strong>GAF</strong> ratings made by <strong>the</strong> interviewer and <strong>the</strong> informant. <strong>The</strong>se were<br />

variable across assessments. For example, most <strong>of</strong> <strong>the</strong> measures <strong>of</strong> symptoms and social<br />

behaviours correlated significantly with <strong>the</strong> <strong>GAF</strong> at 6-month follow-up, but only bizarre<br />

419


420 Mike Startup et al.<br />

Table 1. Inter-rater reliabilities <strong>of</strong> measures, sample sizes and correlations with <strong>the</strong> <strong>GAF</strong><br />

behaviour and ‘mild and severe behaviour’ correlated significantly at <strong>the</strong> initial<br />

assessment. In order to assess <strong>the</strong> independent contributions <strong>of</strong> different kinds <strong>of</strong><br />

symptom and <strong>of</strong> social behaviour to global assessments, three multiple regression<br />

analyses were conducted, one for each assessment. In each <strong>of</strong> <strong>the</strong>se analyses <strong>the</strong> <strong>GAF</strong><br />

was <strong>the</strong> dependent variable and <strong>the</strong> three dimension scores from <strong>the</strong> SANS and SAPS,<br />

toge<strong>the</strong>r with <strong>the</strong> ‘mild and severe behaviour’ index, were entered as predictors. At<br />

intake, <strong>the</strong> multiple correlation (R = .37) was only marginally significant<br />

(F(4,59) = 2.37, p = .06), but at 6-month follow-up (R = .77, F(4,43) =15.9,<br />

p < .0001) and at 12-month follow-up (R = .76, F(4,40) =13.8, p < .0001) <strong>the</strong> multiple<br />

correlations were both large and highly significant. Table 1 shows <strong>the</strong> partial<br />

correlations from <strong>the</strong>se analyses. <strong>The</strong>se reveal that all four predictors made significant<br />

independent contributions at 6 months though only negative symptoms and social<br />

behaviour had significant partial correlations at 12 months.<br />

Discussion<br />

Intake Six-month follow-up 12-month follow-up<br />

ICC r pr ICC r pr ICC r pr<br />

<strong>GAF</strong> .89 .94 .95<br />

Symptoms: N 64 48 45<br />

SANS total .88 –.12 –.10 .71 –.49* –.44* .96 –.63* –.54*<br />

Affective flattening .86 –.06 .83 –.36* .95 –.35*<br />

Alogia .94 .02 .00 –.31* .74 –.27<br />

Avolition .80 –.18 .81 –.39* .93 –.49*<br />

Anhedonia .63 –.13 .86 –.44* .97 –.71*<br />

SAPS: psychotic dimension .94 .08 .10 .92 –.48* –.38* .97 –.15 –.07<br />

Hallucinations .94 .11 .88 –.36* .96 –.04<br />

Delusions .75 –.04 .93 –.57* .96 –.24<br />

SAPS: disorganization .89 –.23 –.15 .84 –.40* –.40* .73 –.29 –.01<br />

Thought disorder .99 –.08 .§ –.17 .§ –.24<br />

Bizarre behaviour –.25* –.46* –.21<br />

Social behaviour schedule: N 64 56 50<br />

Mild and severe behaviour .96 –.31* –.27* .94 –.59* –.39* .98 –.64* –.46*<br />

Thought disturbance .96 –.15 .98 –.54* .99 –.56*<br />

Social withdrawal .97 –.16 .72 –.32* .96 –.39*<br />

Depressed behaviour .63 –.14 .96 –.10 .92 –.51*<br />

Anti-social behaviour .96 –.19 .96 –.20 .98 –.23<br />

* p < .05.<br />

Notes: ICC = intraclass correlations, all significant at p < .05 except for alogia at six months; r = zeroorder<br />

correlations; pr = partial correlations from multiple regression analyses; SANS = Scale for <strong>the</strong><br />

<strong>Assessment</strong> <strong>of</strong> Negative Symptoms; SAPS = Scale for <strong>the</strong> <strong>Assessment</strong> <strong>of</strong> Positive Symptoms;<br />

§ = insufficient variance to calculate ICC.<br />

Inter-rater reliabilities for <strong>the</strong> <strong>GAF</strong> were excellent at all three assessments even though<br />

<strong>the</strong> informants received only very brief introductions to <strong>the</strong> instrument. <strong>The</strong>se results


confirm <strong>the</strong> finding <strong>of</strong> Jones, Thornicr<strong>of</strong>t, C<strong>of</strong>fey, and Dunn (1995) that raters who are<br />

mental health pr<strong>of</strong>essionals need only a brief training in order to use <strong>the</strong> scale reliably.<br />

<strong>The</strong> multiple correlations between <strong>the</strong> <strong>GAF</strong> and <strong>the</strong> measures <strong>of</strong> symptoms and<br />

social behaviour were large and highly significant at <strong>the</strong> follow-up assessments, but not<br />

at intake. This pattern is similar to that reported for <strong>the</strong> GAS (Endicott et al., 1976) and<br />

may be explained largely by <strong>the</strong> reduced variability <strong>of</strong> <strong>the</strong> measures at intake; for<br />

example, <strong>the</strong> variance <strong>of</strong> <strong>the</strong> <strong>GAF</strong> was at least three times greater at <strong>the</strong> follow-ups.<br />

Although <strong>the</strong> multiple correlations were almost <strong>the</strong> same at <strong>the</strong> two follow-ups, <strong>the</strong><br />

patterns <strong>of</strong> partial correlations were somewhat different. At 6 months, all <strong>of</strong> <strong>the</strong><br />

variables, including <strong>the</strong> psychotic and disorganized dimensions, made significant,<br />

independent contributions to <strong>the</strong> prediction <strong>of</strong> <strong>GAF</strong> scores, but at 12 months only<br />

negative symptoms and social behaviour made significant contributions. This pattern<br />

might be explained if <strong>the</strong>re was a tendency for negative symptoms and social behaviour<br />

to be more disabling than positive symptoms at 12 months but equally disabling at 6<br />

months. However, this explanation cannot be tested with <strong>the</strong> present data.<br />

In conclusion, <strong>the</strong> <strong>GAF</strong> provides a valid summary <strong>of</strong> symptoms and social functioning<br />

among schizophrenic patients provided <strong>the</strong>y are not assessed when suffering from<br />

acute psychotic episodes. Since it has been found (Endicott et al., 1976) that global<br />

measures are more sensitive to change than measures <strong>of</strong> single symptom dimensions,<br />

<strong>the</strong> <strong>GAF</strong> has a valuable role in monitoring <strong>the</strong> effects <strong>of</strong> clinical interventions over time<br />

and in outcome research with limited statistical power and, since it can be rated reliably<br />

by mental health pr<strong>of</strong>essionals after minimal training, such monitoring can easily be<br />

integrated with routine community care. Jones et al. (1995) found that <strong>the</strong> <strong>GAF</strong> scores<br />

<strong>of</strong> severely mentally ill patients are associated with <strong>the</strong>ir current support needs, and<br />

that increases in support in <strong>the</strong> preceding month are associated with increases in <strong>GAF</strong><br />

ratings. Thus, <strong>the</strong>re is also evidence that <strong>the</strong> <strong>GAF</strong> fulfils <strong>the</strong> hope that axis V ratings will<br />

generally reflect patients’ current need for treatment or care.<br />

Acknowledgements<br />

This research was supported by grant RC/012 from <strong>the</strong> Wales Office <strong>of</strong> Research and<br />

Development for Health & Social Care.<br />

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Received 25 May 2001; revised version received 9 January 2002

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