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JAEA-Review-2010-065.pdf:15.99MB - 日本原子力研究開発機構

JAEA-Review-2010-065.pdf:15.99MB - 日本原子力研究開発機構

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3-50<br />

Uniformity Measurement of Newly Installed Camera<br />

Heads of Positron-emitting Tracer Imaging System<br />

N. Kawachi a) , N. Suzui a) , S. Ishii a) , H. Yamazaki a), b) and S. Fujimaki a)<br />

a) Radiation-Applied Biology Division, QuBS, <strong>JAEA</strong>,<br />

b) Faculty of Science and Technology, Tokyo University of Science<br />

A positron-emitting tracer imaging system (PETIS) is the<br />

most promising device that can be used for radiotracer<br />

imaging in plant studies. Elucidation of nutrient dynamics<br />

in a plant is important from an agricultural viewpoint in<br />

terms of the growth and development of a plant body; this<br />

helps in understanding the mechanisms underlying nutrient<br />

kinetics using the PETIS. Here, we have performed<br />

phantom experiments for the quarterly maintenance of the<br />

uniformity and sensitivity correction of the PETIS to assess<br />

the performance of its newly installed detector head and<br />

maintain a sufficiently high image quality for plant study.<br />

In order to quantitatively acquire the analyzable dynamic<br />

data of PETIS images, it is mandatory to begin a scheduled<br />

work for constant quality control.<br />

We prepared a flat uniform phantom containing a<br />

radioactive solution of Na-22 (half-life; 2.6 years), and the<br />

radioactivity of the solution was 16.3 kBq/mL. The<br />

phantom had a thickness of 3 mm, a width of 90 mm, and a<br />

height of 90 mm. We have operated three types of the<br />

PETIS detector head (Hamamatsu Photonics Co. [1]).<br />

Newly installed PETS No. 4 and elderly PETIS No. 2,<br />

which has a large field of view, and No. 3, which has fine<br />

detector module, acquired for 5 min to image the phantom in<br />

this maintenance experiment. All images were corrected<br />

for detector geometry and counting rate losses. To analyze<br />

the image quality of the phantom data, we estimated the<br />

mean value (MEAN), standard deviation (SD), and the root<br />

mean square uncertainty (RMSU) of a selected region of<br />

interest (ROI) in the images. %RMSU is defied as follows,<br />

100 <br />

%RMSU <br />

where is the standard deviation, and x is the mean value<br />

of the count in ROI.<br />

Figure 1 shows the imaging results of the phantom<br />

experiments performed with PETIS No. 3 and No. 4. The<br />

phantom image acquired with PETIS No. 3 has a sharper<br />

pattern than those acquired with PETIS No. 4; on the other<br />

hand, the phantom image obtained with PETIS No. 4 has<br />

more uniformity than that obtained with PETIS No. 3. The<br />

crosshatching pattern on the image of PETIS No. 3 indicates<br />

that the errors of geometry correction and sensitivity<br />

dispersions are caused by the aged deterioration of the<br />

detector modules. Results of uniformity analysis of<br />

MEAN, SD, and %RMSU for an active image area are<br />

summarized in Table 1. The analyzed data support the<br />

impression of the visualized phantom images. PETIS No. 4<br />

exhibited excellent uniformity performance for plant study.<br />

x<br />

<strong>JAEA</strong>-<strong>Review</strong> <strong>2010</strong>-065<br />

- 106 -<br />

(PETIS No. 3) (PETIS No. 4)<br />

Fig. 1 Images of radioactive flat phantom ( 22 Na;<br />

390 kBq) acquired for 5 minutes with PETIS No. 3<br />

(left) and PETIS No. 4 (right).<br />

Table 1 Analyzed performance of MEAN, SD,<br />

and %RMSU for the active image area of the PETIS<br />

detector head of No. 2, No. 3, and No. 4.<br />

MEAN<br />

S. D.<br />

%RMSU<br />

PETIS<br />

No. 2<br />

6.89 × 10-4<br />

7.63 ×10 -5<br />

PETIS<br />

No. 3<br />

PETIS<br />

No. 4<br />

7.14 × 10-4 3.56 × 10-4<br />

1.23 × 10-4 1.46 × 10-5<br />

11.1 17.2 4.11<br />

The %RMSU is expected to increase in the activity of the<br />

images; therefore, the measurements of %RMSU<br />

dependence on the counting rate in each detector head are<br />

now in progress. These works on the maintenance of<br />

PETIS quality control ensure quantitative kinetic analysis<br />

and support many other plant physiological experiments of<br />

PETIS studies.<br />

Reference<br />

1) H. Uchida et al., Nucl. Instrum. Meth. A 516 (2004)<br />

564.

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