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Bernardini et al., PNAS,<br />
1989<br />
IcsA<br />
Glycin-rich repe<strong>at</strong>s<br />
Activ<strong>at</strong>ion<br />
of N-WASP<br />
3<br />
G-actin<br />
2<br />
3 2<br />
Arp2/3complex<br />
Capping<br />
protein<br />
F-actin<br />
Activ<strong>at</strong>ion of<br />
Arp2/3 complex<br />
3<br />
3<br />
α-actinin<br />
2<br />
2<br />
3<br />
2<br />
Tread milling<br />
ADF/Profilin<br />
IcsA<br />
vacuole lysis<br />
(TTSS)<br />
epithelial cells<br />
basol<strong>at</strong>eral<br />
macropinocytosis<br />
(TTSS)<br />
mucus<br />
motility<br />
cell to cell spread<br />
(TTSS)
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