14.07.2013 Views

Prions: Protein Aggregation and Infectious Diseases - Physiological ...

Prions: Protein Aggregation and Infectious Diseases - Physiological ...

Prions: Protein Aggregation and Infectious Diseases - Physiological ...

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

1144 ADRIANO AGUZZI AND ANNA MARIA CALELLA<br />

169. Gabizon R, McKinley MP, Prusiner SB. Purified prion proteins<br />

<strong>and</strong> scrapie infectivity copartition into liposomes. Proc Natl Acad<br />

Sci USA 84: 4017–4021, 1987.<br />

170. Gabriel JM, Oesch B, Kretzschmar H, Scott M, Prusiner SB.<br />

Molecular cloning of a c<strong>and</strong>idate chicken prion protein. Proc Natl<br />

Acad Sci USA 89: 9097–9101, 1992.<br />

171. Gajdusek D, Zigas V. Clinical, pathological <strong>and</strong> epidemiological<br />

study of an acute progressive degenerative disease of the central<br />

nervous system among natives of the eastern higl<strong>and</strong>s of New<br />

Guinea. Am J Med 26: 442–469, 1959.<br />

172. Gajdusek DC. Unconventional viruses <strong>and</strong> the origin <strong>and</strong> disappearance<br />

of kuru. Science 197: 943–960, 1977.<br />

173. Gajdusek DC, Zigas V. Degenerative disease of the central nervous<br />

system in New Guinea: the endemic occurrence of “kuru” in<br />

the native population. N Engl J Med 257: 974–978, 1957.<br />

174. Gambetti P, Kong Q, Zou W, Parchi P, Chen SG. Sporadic <strong>and</strong><br />

familial CJD: classification <strong>and</strong> characterisation. Br Med Bull 66:<br />

213–239, 2003.<br />

175. Gambetti P, Parchi P, Petersen RB, Chen SG, Lugaresi E.<br />

Fatal familial insomnia <strong>and</strong> familial Creutzfeldt-Jakob disease: clinical,<br />

pathological <strong>and</strong> molecular features. Brain Pathol 5: 43–51,<br />

1995.<br />

176. Gasset M, Baldwin MA, Fletterick RJ, Prusiner SB. Perturbation<br />

of the secondary structure of the scrapie prion protein under<br />

conditions that alter infectivity. Proc Natl Acad Sci USA 90: 1–5,<br />

1993.<br />

177. Genoud N, Behrens A, Miele G, Robay D, Heppner FL,<br />

Freigang S, Aguzzi A. Disruption of Doppel prevents neurodegeneration<br />

in mice with extensive Prnp deletions. Proc Natl Acad<br />

Sci USA 101: 4198–4203, 2004.<br />

178. Genoud N, Ott D, Braun N, Prinz M, Schwarz P, Suter U,<br />

Trono D, Aguzzi A. Antiprion prophylaxis by gene transfer of a<br />

soluble prion antagonist. Am J Pathol 172: 1287–1296, 2008.<br />

179. Gerstmann J, Sträussler E, Scheinker I. über eine eigenartige<br />

hereditär-familiäre Erkrankung des Zentralnervensystems. Zugleich<br />

ein Beitrag zur Frage des vorzeitigen lokalen Alterns Z<br />

Neurol 154: 736–762, 1936.<br />

180. Ghani AC, Donnelly CA, Ferguson NM, Anderson RM. Assessment<br />

of the prevalence of vCJD through testing tonsils <strong>and</strong> appendices<br />

for abnormal prion protein. Proc Biol Sci 267: 23–29, 2000.<br />

181. Ghani AC, Ferguson NM, Donnelly CA, Hagenaars TJ, Anderson<br />

RM. Estimation of the number of people incubating variant<br />

CJD. Lancet 352: 1353–1354, 1998.<br />

182. Gibbons RA, Hunter GD. Nature of the scrapie agent. Nature 215:<br />

1041–1043, 1967.<br />

183. Glatzel M, Abela E, Maissen M, Aguzzi A. Extraneural pathologic<br />

prion protein in sporadic Creutzfeldt-Jakob disease. N Engl<br />

J Med 349: 1812–1820, 2003.<br />

184. Glatzel M, Aguzzi A. PrP(C) expression in the peripheral nervous<br />

system is a determinant of prion neuroinvasion. J Gen Virol 81:<br />

2813–2821, 2000.<br />

185. Glatzel M, Aguzzi A. The shifting biology of prions. Brain Res<br />

Brain Res Rev 36: 241–248, 2001.<br />

186. Glatzel M, Heppner FL, Albers KM, Aguzzi A. Sympathetic<br />

innervation of lymphoreticular organs is rate limiting for prion<br />

neuroinvasion. Neuron 31: 25–34, 2001.<br />

187. Glatzel M, Ott PM, Lindner T, Gebbers JO, Gmur A, Wuest W,<br />

Huber G, Moch H, Podvinec M, Stamm B, Aguzzi A. Human<br />

prion diseases: epidemiology <strong>and</strong> integrated risk assessment. Lancet<br />

Neurol 2: 757–763, 2003.<br />

188. Glaysher BR, Mabbott NA. Role of the draining lymph node in<br />

scrapie agent transmission from the skin. Immunol Lett 109: 64–71,<br />

2007.<br />

189. Glaysher BR, Mabbott NA. Role of the GALT in scrapie agent<br />

neuroinvasion from the intestine. J Immunol 178: 3757–3766, 2007.<br />

190. Glockshuber R, Hornemann S, Billeter M, Riek R, Wider G,<br />

Wuthrich K. Prion protein structural features indicate possible<br />

relations to signal peptidases. FEBS Lett 426: 291–296, 1998.<br />

191. Gommerman JL, Browning JL. Lymphotoxin/light, lymphoid microenvironments<br />

<strong>and</strong> autoimmune disease. Nat Rev Immunol 3:<br />

642–655, 2003.<br />

192. Gommerman JL, Mackay F, Donskoy E, Meier W, Martin P,<br />

Browning JL. Manipulation of lymphoid microenvironments in<br />

Physiol Rev VOL 89 OCTOBER 2009 www.prv.org<br />

nonhuman primates by an inhibitor of the lymphotoxin pathway.<br />

J Clin Invest 110: 1359–1369, 2002.<br />

193. Goni F, Prelli F, Schreiber F, Scholtzova H, Chung E, Kascsak<br />

R, Brown DR, Sigurdsson EM, Chabalgoity JA, Wisniewski T.<br />

High titers of mucosal <strong>and</strong> systemic anti-PrP antibodies abrogate<br />

oral prion infection in mucosal-vaccinated mice. Neuroscience 153:<br />

679–686, 2008.<br />

194. Gordon WS. Advances in veterinary research. Vet Res 58: 516–520,<br />

1946.<br />

195. Gorodinsky A, Harris DA. Glycolipid-anchored proteins in neuroblastoma<br />

cells form detergent-resistant complexes without<br />

caveolin. J Cell Biol 129: 619–627, 1995.<br />

196. Green KM, Castilla J, Seward TS, Napier DL, Jewell JE, Soto<br />

C, Telling GC. Accelerated high fidelity prion amplification within<br />

<strong>and</strong> across prion species barriers. PLoS Pathog 4: e1000139, 2008.<br />

197. Griffith JS. Self-replication <strong>and</strong> scrapie. Nature 215: 1043–1044,<br />

1967.<br />

198. Haik S, Faucheux BA, Sazdovitch V, Privat N, Kemeny JL,<br />

Perret-Liaudet A, Hauw JJ. The sympathetic nervous system is<br />

involved in variant Creutzfeldt-Jakob disease. Nat Med 9: 1121–<br />

1122, 2003.<br />

199. Hainfellner JA, Brantner Inthaler S, Cervenakova L, Brown<br />

P, Kitamoto T, Tateishi J, Diringer H, Liberski PP, Regele H,<br />

Feucht M. The original Gerstmann-Straussler-Scheinker family of<br />

Austria: divergent clinicopathological phenotypes but constant PrP<br />

genotype. Brain Pathol 5: 201–211, 1995.<br />

200. Hamir AN, Kunkle RA, Miller JM, Hall SM. Abnormal prion<br />

protein in ectopic lymphoid tissue in a kidney of an asymptomatic<br />

white-tailed deer experimentally inoculated with the agent of<br />

chronic wasting disease. Vet Pathol 43: 367–369, 2006.<br />

201. Haraguchi T, Fisher S, Olofsson S, Endo T, Groth D, Tarentino<br />

A, Borchelt DR, Teplow D, Hood L, Burlingame A.<br />

Asparagine-linked glycosylation of the scrapie <strong>and</strong> cellular prion<br />

proteins. Arch Biochem Biophys 274: 1–13, 1989.<br />

202. Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer’s disease:<br />

progress <strong>and</strong> problems on the road to therapeutics. Science<br />

297: 353–356, 2002.<br />

203. Healy DL, Evans J. Creutzfeldt-Jakob disease after pituitary gonadotrophins.<br />

BMJ 307: 517–518, 1993.<br />

204. Hegde RS, Mastrianni JA, Scott MR, DeFea KA, Tremblay P,<br />

Torchia M, DeArmond SJ, Prusiner SB, Lingappa VR. A transmembrane<br />

form of the prion protein in neurodegenerative disease.<br />

Science 279: 827–834, 1998.<br />

205. Hegde RS, Tremblay P, Groth D, DeArmond SJ, Prusiner SB,<br />

Lingappa VR. Transmissible <strong>and</strong> genetic prion diseases share a<br />

common pathway of neurodegeneration Nature 402: 822–826, 1999.<br />

206. Heikenwalder M, Federau C, von Boehmer L, Schwarz P,<br />

Wagner M, Zeller N, Haybaeck J, Prinz M, Becher B, Aguzzi A.<br />

Germinal center B cells are dispensable in prion transport <strong>and</strong><br />

neuroinvasion. J Neuroimmunol 192: 113–123, 2007.<br />

207. Heikenwalder M, Julius C, Aguzzi A. <strong>Prions</strong> <strong>and</strong> peripheral<br />

nerves: a deadly rendezvous. J Neurosci Res 85: 2714–2725, 2007.<br />

208. Heikenwalder M, Kurrer MO, Margalith I, Kranich J, Zeller N,<br />

Haybaeck J, Polymenidou M, Matter M, Bremer J, Jackson<br />

WS, Lindquist S, Sigurdson CJ, Aguzzi A. Lymphotoxin-dependent<br />

prion replication in inflammatory stromal cells of granulomas.<br />

Immunity 29: 998–1008, 2008.<br />

209. Heikenwalder M, Polymenidou M, Junt T, Sigurdson C, Wagner<br />

H, Akira S, Zinkernagel R, Aguzzi A. Lymphoid follicle<br />

destruction <strong>and</strong> immunosuppression after repeated CpG oligodeoxynucleotide<br />

administration. Nat Med 10: 187–192, 2004.<br />

210. Heikenwalder M, Zeller N, Seeger H, Prinz M, Klohn PC,<br />

Schwarz P, Ruddle NH, Weissmann C, Aguzzi A. Chronic lymphocytic<br />

inflammation specifies the organ tropism of prions. Science<br />

307: 1107–1110, 2005.<br />

211. Hemmi H, Takeuchi O, Kawai T, Kaisho T, Sato S, Sanjo H,<br />

Matsumoto M, Hoshino K, Wagner H, Takeda K, Akira S. A<br />

Toll-like receptor recognizes bacterial DNA. Nature 408: 740–745,<br />

2000.<br />

212. Heppner FL, Christ AD, Klein MA, Prinz M, Fried M, Kraehenbuhl<br />

JP, Aguzzi A. Transepithelial prion transport by M cells.<br />

Nat Med 7: 976–977, 2001.

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!