Insect Immunity & Drosophila Gut Immune Response
Insect Immunity & Drosophila Gut Immune Response Insect Immunity & Drosophila Gut Immune Response
Absence of infection Severe infection bacteria Imd pathway RELISH Imd Imd Imd pathway RELISH pathway pathway RELISH RELISH
The Imd pathway is activated throughout the gut, BUT Diptericin shows patterned expression Diptericin-lacZ ? PGRP LC Imd pathway κB κB κB Control Caudal Diptericin Caudal RNAi Ryu et al (2008) Science 319 ⇒ additional regulatory elements restrict Diptericin expression in some gut cells.
- Page 1 and 2: Bruno Lemaitre Global Health Instit
- Page 3 and 4: The enemies of insects • Viruses:
- Page 5 and 6: Bacillus thuringiensis - Gram-posit
- Page 8: Plasmodium development in Anopheles
- Page 11 and 12: A wasp parasitizing of Drosophila l
- Page 13 and 14: Drosophila antiviral defense 1) RNA
- Page 15 and 16: Physical and chemical barriers Chit
- Page 17 and 18: Cellular immunity Cell type plasmat
- Page 19: Activation of melanization Melaniza
- Page 23 and 24: The Gut - Site of digestion - Major
- Page 25 and 26: Wild-type E. coli DAP-PGN LYS- PGN
- Page 27: PGRP-LB Western Blot (gut extracts)
- Page 31 and 32: Tolerance to gut indigenous flora
- Page 33 and 34: Major Remodeling of the Gut upon gu
- Page 35 and 36: Mitosis marker staining : phospho h
- Page 37 and 38: Epithelium stress & damage Bacteria
- Page 39 and 40: WT JAK-STAT deficient Unchallenged
- Page 41 and 42: Intestinal muscles Intestinal epith
- Page 43 and 44: Pe-GFP Control P. entomophila
- Page 45 and 46: Two important host defense mechanis
- Page 47 and 48: Collaborators GHI, EPFL, Lausan
- Page 49 and 50: Imd deficient flies have a higher b
- Page 51 and 52: The EGFR pathway coordinates Drosop
- Page 53: Esg‐GFP : Stem cells, e
Absence of infection Severe infection<br />
bacteria<br />
Imd<br />
pathway<br />
RELISH<br />
Imd<br />
Imd<br />
Imd<br />
pathway<br />
RELISH<br />
pathway pathway<br />
RELISH RELISH
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