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2nd ANNUAL<br />

<strong>Florida</strong> <strong>Oncology</strong> <strong>Symposium</strong>:<br />

Clinical Pathways to Personalized Medicine<br />

May 5 – 7, 2011<br />

The Ritz-Carlton Hotel<br />

Naples, <strong>Florida</strong>


<strong>Florida</strong> <strong>Oncology</strong> <strong>Symposium</strong>:<br />

Clinical Pathways to Personalized Medicine<br />

May 5 – 7, 2011 The Ritz-Carlton Hotel | Naples, <strong>Florida</strong><br />

COURSE DESCRIPTION<br />

Our second symposium offers learning opportunities and<br />

networking for those clinicians wanting to learn more about<br />

the latest clinical research applications to patient care in the<br />

diagnosis and management of various cancers: Hematology,<br />

Genitourinary Cancers, Melanoma, HPV and Sarcoma.<br />

In addition, an update on the progress of Moffitt’s newly<br />

developed clinical pathways will be offered as a concurrent<br />

breakout session. These pathways have been developed to<br />

assist and to improve clinical outcomes in these disease sites:<br />

breast, prostate, lung, acute leukemia, sarcoma and pancreas.<br />

The objective is to catalyze clinician consensus and to reduce<br />

clinician variation toward the best possible outcome given<br />

a patient’s unique clinical factors, genetics, and personal<br />

preferences. These pathways are primarily designed to support<br />

the administration of therapies proven to optimize efficacy and<br />

reduce toxicity, and secondarily to manage cost when prudent<br />

choices between clinically similar alternatives can drive more<br />

affordable, quality care.<br />

We are proud to share<br />

the early progress<br />

toward clinical pathways<br />

development with the<br />

conference participants<br />

to achieve an even<br />

better product by<br />

incorporating related<br />

feedback and<br />

collaboration.<br />

TARGET AUDIENCE<br />

This educational activity<br />

is planned to meet the<br />

educational needs of<br />

clinical and surgical oncologists in both academia and private<br />

practice. Primary care physicians and nurses in oncology will<br />

benefit from the presentations and small group discussions in<br />

the latest cancer treatment modalities.<br />

PROGRAM OBJECTIVES<br />

Upon completion of this program, participants should<br />

be able to:<br />

• Discuss circulating tumor cells and how they can serve<br />

as a new platform to provide personalized medicine.<br />

• To tailor therapies for chronic leukemias.<br />

• Understand how HPV vaccination can be used to<br />

prevent different cancers in both women and men.<br />

• Assess the current role of robotic cystectomy in the<br />

management of localized bladder cancer.<br />

• Evaluate management options for prostate, bladder<br />

and kidney cancer.<br />

• Describe new drugs and targets that are important<br />

in early phase clinical trials.<br />

• Discuss the diagnosis and treatment of GIST,<br />

soft tissue and bone sarcomas.<br />

• Recognize how clinical pathways use a patient’s genetic<br />

signature to formulate personalized therapy.<br />

• Recognize the benefits of immunotherapy for<br />

melanoma and hematologic malignancies.<br />

ACCREDITATION<br />

Physicians USF Health is accredited by the Accreditation<br />

Council for Continuing Medical Education to provide continuing<br />

medical education for physicians.<br />

USF Health designates this educational activity for a maximum<br />

of 16.25 AMA PRA Category 1 Credits . Physicians should only<br />

claim credit commensurate with the extent of their participation<br />

in the activity.<br />

Nurses The University of South <strong>Florida</strong> College of Nursing<br />

is accredited as a provider of continuing nursing education<br />

by the American Nurses Credentialing Center’s Commission<br />

on Accreditation.<br />

A maximum of 16.25 contact hours may be earned by<br />

learners who successfully complete this continuing nursing<br />

education activity.


AGENDA<br />

MAY 5, 2011 | THURSDAY<br />

11:00 am – 7:00 pm Registration<br />

12:45 – 1:00 pm Welcome and Introduction<br />

Daniel Sullivan, MD<br />

1:00 – 3:00 pm Personalized Medicine:<br />

New and Exciting Molecular Platforms<br />

Chairperson: Timothy Yeatman, MD, FACS<br />

• Circulating Tumor Cells as a Guide to Personalized<br />

Medicine in Cancer — David Nelson, PhD<br />

• Integrating Biomarkers into Colorectal Cancer Clinical<br />

Trials — Scott Kopetz, MD, PhD<br />

• The “Next Generation” of Translational <strong>Oncology</strong> —<br />

Levi Garraway, MD, PhD<br />

3:00 – 3:15 pm Break<br />

3:15 – 5:15 pm Molecular Determinants of Response<br />

in Clinical <strong>Oncology</strong><br />

• Microarrays for Diagnosis, Prognosis and Treatment<br />

Planning of Breast Cancer — Stefan Glück, MD, PhD, FRCPC<br />

• Biomarkers That Determine Response in Multiple Myeloma<br />

and Non-Hodgkin’s Lymphoma — Steven Grant, MD<br />

• Biomarker-Driven Trials in Ovarian Cancer —<br />

Johnathan Lancaster, MD, PhD<br />

• Bio-marker Driven Trials in NSCLC — Scott Antonia, MD, PhD<br />

7:00 – 9:00 pm Dinner with Keynote speaker<br />

Molecular Signatures for Guiding Therapies of<br />

Non-Small Cell Lung Cancer<br />

David Carbone, MD, PhD<br />

MAY 6, 2011 | FRIDAY<br />

7:00 – 7:55 am Breakfast and Exhibits<br />

7:55 – 8:00 am Welcome and Introduction<br />

Alan List, MD, Course Director<br />

8:00 - 10:00 am SESSION 1: Hematology/<strong>Oncology</strong><br />

Chairperson: Eduardo Sotomayor, MD<br />

• AML in the Elderly: New Therapies — Jeffrey Lancet, MD<br />

• Consolidation therapy in AML: Should we transplant<br />

everyone? — Hugo Fernandez, MD<br />

• Targeted Therapies for Chronic Leukemias —<br />

Javier Pinilla-Ibarz, MD, PhD<br />

• Radioimmunotherapy for Hematologic Malignancies —<br />

Michael Tomblyn, MD<br />

10:00 – 10:30 am Break and Exhibits<br />

10:30 – 11:30 am SESSION 2: Prevention of HPV –<br />

Related Cancers: Current Practice and<br />

Future Horizons<br />

Chairperson: Dana Rollison, PhD<br />

• Cancer Prevention through HPV Vaccination in Men<br />

and Women — Kevin Collins, MD<br />

• Cutaneous HPV and Non-Melanoma Skin Cancer —<br />

Dana Rollison, PhD<br />

11:30 am – 12:45 pm Luncheon with Keynote Speaker<br />

Quality, Measurement and Economics of<br />

Health Care Systems<br />

Lisa Slama, PhD<br />

12:45 – 2:30 pm SESSION 3: Genitourinary Cancers<br />

Chairperson: Julio Pow-Sang, MD<br />

• Active Surveillance and Surgical Options for Localized<br />

Prostate Cancer — Julio Pow-Sang, MD<br />

• Radiation Therapy Options for Localized Prostate Cancer -<br />

Richard Wilder, MD<br />

(FRIDAY CONTINUED)<br />

• Treatment Options for Hormone Refractory Prostate<br />

Cancer — Jingsong Zhang, MD, PhD<br />

• Management Options for Small Renal Tumors —<br />

Philippe Spiess, MD<br />

• Emerging Role of Robotic Cystectomy in the Management<br />

of Invasive Bladder Cancer — Wade Sexton, MD<br />

2:30 - 4:30 pm SESSION 4: Moffitt Pathways<br />

Chairperson: Robert Wenham, MD<br />

2:30 – 3:00 pm Pathways to Improving Clinical Outcomes<br />

Mark Schippits, MD<br />

3:00 - 3:30 pm Break and Exhibits<br />

3:30 – 4:00 pm Break Out Sessions (select one)<br />

• Breast — Hatem Soliman, MD<br />

• Prostate — Mayer Fishman, MD, PhD and J. Zhang, MD, PhD<br />

• Lung — Mary Pinder, MD<br />

• Acute Leukemia — Jeffrey Lancet, MD<br />

• Sarcoma — Damon Reed, MD<br />

• Pancreatic — Gregory Springett, MD, PhD<br />

4:00 – 4:30 pm Break Out Sessions Repeated (select one)<br />

• Breast — Hatem Soliman, MD<br />

• Prostate — Mayer Fishman, MD, PhD and J. Zhang, MD, PhD<br />

• Lung — Mary Pinder, MD<br />

• Acute Leukemia — Jeffrey Lancet, MD<br />

• Sarcoma — Damon Reed, MD<br />

• Pancreatic — Gregory Springett, MD, PhD<br />

Evening on Your Own<br />

MAY 7, 2011 | SATURDAY<br />

7:00 – 8:00 am Breakfast<br />

8:00 – 9:30 am SESSION 5: Advances in the Treatment of<br />

Metastatic Melanoma<br />

Chairperson: Jeffrey Weber, MD, PhD<br />

• INTRODUCTION: Melanoma: Poster Child for Novel and<br />

Targeted Therapies — Jeffrey Weber, MD, PhD<br />

• Regional Treatment for Melanoma: Liver or Limb? —<br />

Jonathan Zager, MD<br />

• Targeted Therapy for Melanoma is Here At Last —<br />

Ragini Kudchadkar, MD<br />

• Novel Immunotherapies for Melanoma Prolong Survival —<br />

Jeffrey Weber, MD, PhD<br />

9:30 – 10:00 am Break and Exhibits<br />

10:00 – 11:30 am SESSION 6: Advances in Drug Development<br />

Chairperson: Saïd Sebti, MD, PhD<br />

• Targeting the Akt Pathway: From Basic Science to<br />

Hypothesis-driven Clinical Trials — Saïd Sebti, MD, PhD<br />

• Disruptors of the Binding of Raf1 Kinase to the<br />

Tumor Suppressor Rb as Novel Anticancer Drugs —<br />

Kumar Chellappan, MD<br />

• Targeting Shp2 Protein Phosphatase for Drug Discovery —<br />

Jerry Wu, MD<br />

11:30 am – 1:00 pm Lunch with Guest Speaker<br />

1:00 – 2:30 pm SESSION 7: Sarcoma<br />

Chairperson: Douglas Letson, MD<br />

• GIST — Updates and Future Direction — Rick Gonzalez, MD<br />

• Bone Sarcomas: What Have we Learned and Where are<br />

the Opportunities for Improvement? — Damon Reed, MD<br />

• Soft Tissue Sarcoma: Breaking Tradition —<br />

Anthony Conley, MD<br />

2:30 pm Closing Remarks/Conference Adjourns


Name ____________________________________________________________<br />

Degree/Credentials ________________________________________________<br />

Date of Birth (MM/DD) _________________ Specialty ________________<br />

License #__________________________________________________________<br />

Organization ______________________________________________________<br />

Address __________________________________________________________<br />

City________________________________ State_________ ZIP __________<br />

Phone________________________ Fax ________________________________<br />

E-mail ____________________________________________________________<br />

Attendance Thursday keynote dinner ❏ Yes ❏ No<br />

Attendance Saturday night dinner ❏ Yes ❏ No<br />

❏ Complimentary nurse registration accompanying physician<br />

Name ____________________________________________________________<br />

License #__________________________________________________________<br />

E-mail ____________________________________________________________<br />

FEES<br />

REGISTRATION FORM<br />

FLORIDA ONCOLOGY SYMPOSIUM<br />

May 5 – 7, 2011<br />

The Ritz-Carlton Hotel | Naples, <strong>Florida</strong><br />

REGISTRATION FEE INCLUDES:<br />

Conference materials and all meal functions during conference.<br />

Attendance Thursday keynote dinner ❏ Yes ❏ No<br />

Attendance Saturday night dinner ❏ Yes ❏ No<br />

Please place a check mark next to your registration type.<br />

❏ Physician ..............................................................................................$225.00<br />

❏ Physician Assistant ..................................................................$1 75.00<br />

❏ Nurse ............................................................................................$1 75.00<br />

❏ Other Health Care Professional ..............................................$150.00<br />

Dinner Guests<br />

❏ Thursday night dinner ................................................................$40.00<br />

# of guests _____<br />

❏ Saturday night reception and dinner ....................................$75.00<br />

# of guests _____<br />

❏ Children (7-14) Saturday dinner ............................................$25.00<br />

# of children _____<br />

TOTAL AMOUNT $______________<br />

On-line registration deadline May 2, 2011.<br />

On-site registration will be available.<br />

PAYMENT METHOD<br />

❏ Check (payable to Moffitt Cancer Center)<br />

❏ MasterCard ❏ Visa ❏ American Express ❏ Discover<br />

Amount $______________<br />

Credit Card # ______________________________________________________<br />

Expiration Date ____________________________________________________<br />

Cardholder Name __________________________________________________<br />

Signature ________________________________________________________<br />

REGISTRATION OPTIONS<br />

• On-line at www.moffitt.org/FOS2011<br />

• Paper Registration, please mail along with payment to:<br />

Moffitt Cancer Center<br />

MBC-CONFPLAN<br />

12902 Magnolia Drive<br />

Tampa, FL 33612-9497<br />

For further information, contact Melissa Pearson at 813-745-1247<br />

or Melissa.Pearson@moffitt.org<br />

REFUND POLICY: An administrative fee of $50.00 will be assessed for cancellations<br />

received on or before April 22, 2011 and no refunds will be issued after this date.<br />

Events, activities, programs and facilities of the University of South <strong>Florida</strong> are available<br />

to all without regard to race, color, marital status, gender, sexual orientation, religion,<br />

national origin, disability, age, Vietnam or disabled veteran status as provided by law<br />

and in accordance with the university’s respect for personal dignity.<br />

USF HPCC is an Equal Opportunity/Equal Access Institution. For disability accommodations<br />

contact USF HPCC at 813-974-7420, a minimum of five (5) working days in advance.<br />

Program # CH 2011401/1160


FACULTY<br />

COURSE DIRECTOR<br />

Alan List, MD<br />

Professor of Medicine & Oncologic Sciences<br />

Executive Vice President & Physician-in-Chief<br />

The Frank & Carol Morsani Endowed Chair<br />

Moffitt Cancer Center<br />

Tampa, <strong>Florida</strong><br />

Guest Faculty<br />

David Carbone, MD, PhD<br />

Professor of Medicine and Cancer Biology<br />

Vanderbilt University Cancer Center<br />

Nashville, Tennessee<br />

Kevin Collins, MD<br />

Director, Clinical Services<br />

Student Health<br />

<strong>Florida</strong> Gulf Coast University<br />

Fort Myers, <strong>Florida</strong><br />

Levi Garraway, MD, PhD<br />

Assistant Professor<br />

Department of Medical <strong>Oncology</strong><br />

Harvard Medical School<br />

Dana-Farber Cancer Institute<br />

Boston, Massachusetts<br />

Stefan Glück, MD, PhD, FRCPC<br />

Sylvester Professor, Department of Medicine<br />

University of Miami<br />

Leonard M. Miller School of Medicine<br />

Assistant Director, Associate Chief<br />

Division of Hematology/<strong>Oncology</strong><br />

Sylvester Comprehensive Cancer Center<br />

Miami, <strong>Florida</strong><br />

Steven Grant, MD<br />

Associate Director, Translational Research<br />

Co-Director, Cancer Cell Biology Program<br />

Virginia Commonwealth University<br />

Massey Cancer Center<br />

Richmond, Virginia<br />

Scott Kopetz, MD, PhD<br />

Assistant Professor<br />

GI Medical <strong>Oncology</strong><br />

University of Texas<br />

M.D. Anderson Cancer Center<br />

Houston, Texas<br />

David Nelson, PhD<br />

President and CEO<br />

Epic Sciences<br />

San Diego, California<br />

Lisa Slama, PhD<br />

Associate Vice President<br />

Sg2<br />

Skokie, Illinois<br />

ACCOMMODATIONS<br />

THE RITZ-CARLTON NAPLES<br />

280 Vanderbilt Beach Road<br />

Naples, <strong>Florida</strong> 34108<br />

239-598-3300<br />

www.ritzcarlton.com<br />

USF Health Faculty<br />

at Moffitt Cancer Center<br />

Scott Antonia, MD, PhD<br />

Professor of Oncologic Sciences<br />

Chairman, Thoracic <strong>Oncology</strong> Department<br />

Co-Leader, Immunology Program<br />

Srikumar Chellappan, PhD<br />

Professor of Molecular Medicine & Oncologic Sciences<br />

Professor & Chair, Department of Tumor Biology<br />

Scientific Director, National Functional Genomics Center<br />

Anthony Conley, MD<br />

Assistant Professor of Oncologic Sciences<br />

Sarcoma Program<br />

Hugo Fernandez, MD<br />

Professor of Medicine & Oncologic Sciences<br />

Associate Chair & Clinical Director<br />

Department of Blood & Marrow Transplantation<br />

Mayer Fishman, MD, PhD<br />

Associate Professor of Medicine & Oncologic Sciences<br />

Genitourinary <strong>Oncology</strong><br />

Experimental Therapeutics Program<br />

Ricardo Gonzalez, MD<br />

Assistant Professor of Oncologic Sciences<br />

Surgical Oncologist, Sarcoma Program<br />

& Cutaneous <strong>Oncology</strong><br />

Ragini Kudchadkar, MD<br />

Assistant Professor of Medicine & Oncologic Sciences<br />

Cutaneous <strong>Oncology</strong> Program<br />

Johnathan Lancaster, MD, PhD<br />

Associate Professor, Department of Oncologic Sciences<br />

Chair, Department of Women’s <strong>Oncology</strong><br />

Director, Center for Women's <strong>Oncology</strong><br />

Jeffrey Lancet, MD<br />

Associate Professor of Medicine & Oncologic Sciences<br />

Section Head, Leukemia<br />

Department of Malignant Hematology<br />

Douglas Letson, MD<br />

Professor of Radiology, Orthopaedic <strong>Oncology</strong> & Surgery<br />

Division Chair, Sarcoma Program<br />

Mary Pinder-Schneck, MD<br />

Assistant Professor of Medicine & Oncologic Sciences<br />

Medical <strong>Oncology</strong><br />

Thoracic <strong>Oncology</strong> Program<br />

Javier Pinilla-Ibarz, MD, PhD<br />

Assistant Professor of Medicine & Oncologic Sciences<br />

Department of Malignant Hematology<br />

Julio Pow-Sang, MD<br />

Professor of Surgery & Oncologic Sciences<br />

Chief, Surgery Services<br />

Director, Robotics Program<br />

Department of GU <strong>Oncology</strong><br />

Damon Reed, MD<br />

Assistant Professor of Medicine & Oncologic Sciences<br />

Medical Oncologist, Sarcoma Program<br />

Dana Rollison, PhD<br />

VP/Chief, of Health Informatics<br />

Associate Professor of Oncologic Sciences<br />

Scientific Director, Moffitt Cancer Registry<br />

Co-Scientific Director, Moffitt Tissue Core<br />

Mark Schippits, MD<br />

Director, Clinical Informatics Program<br />

Saïd Sebti, PhD<br />

Professor of Molecular Medicine & Oncologic Sciences<br />

Garcia Endowed Professor & Chair<br />

Director, Drug Discovery Comprehensive<br />

Research Center<br />

Department of Drug Discovery<br />

Wade Sexton, MD<br />

Associate Professor of Oncologic Sciences<br />

Genitourinary Program<br />

Fellowship Director<br />

Hatem Soliman, MD<br />

Assistant Professor of Medicine & Oncologic Sciences<br />

Comprehensive Breast Program<br />

Department of Women’s <strong>Oncology</strong><br />

Eduardo Sotomayor, MD<br />

Professor of Medicine & Oncologic Sciences<br />

Susan and John Sykes Endowed Chair in Malignant<br />

Hematology<br />

Department of Malignant Hematology<br />

Phillip Spiess, MD<br />

Assistant Professor of Oncologic Sciences<br />

Genitourinary <strong>Oncology</strong> & Urology<br />

Gregory Springett, MD, PhD<br />

Assistant Professor of Medicine & Oncologic Sciences<br />

Department of Gastrointestinal <strong>Oncology</strong><br />

Section of Pancreatic <strong>Oncology</strong><br />

Experimental Therapeutics & Drug Discovery Department<br />

Daniel Sullivan, MD<br />

Professor of Medicine,<br />

Molecular Medicine& Oncologic Sciences<br />

Executive Vice President & Associate<br />

Center Director for Clinical Investigations<br />

Leader, Phase I Program<br />

Blood & Marrow Transplantation Department<br />

Michael Tomblyn, MD, MS<br />

Assistant Professor of Medicine & Oncologic Sciences,<br />

Department of Radiation <strong>Oncology</strong><br />

Jeffrey Weber, MD, PhD<br />

Professor of Medicine & Oncologic Sciences<br />

Director, Donald A. Adam Comprehensive<br />

Melanoma Research Center<br />

H. LEE MOFFITT CANCER CENTER & RESEARCH INSTITUTE, AN NCI COMPREHENSIVE CANCER CENTER - TAMPA, FL. 1-888-MOFFITT<br />

© 2011 H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. All rights reserved.<br />

Robert Wenham, MD, MS, FACOG<br />

Assistant Professor of Oncologic Sciences<br />

Clinical Director, Gynecologic <strong>Oncology</strong> Medical Director,<br />

Moffitt Clinical Research Network<br />

Principal Investigator,<br />

Total Cancer Care Department of Women's <strong>Oncology</strong><br />

Richard Wilder, MD, MBA, MS<br />

Associate Professor of Radiology & Oncologic Sciences<br />

Radiation <strong>Oncology</strong>/Genitourinary <strong>Oncology</strong><br />

Department of Radiation <strong>Oncology</strong><br />

Jie Wu, PhD<br />

Professor of Molecular Medicine & Oncologic Sciences<br />

Department of Molecular <strong>Oncology</strong><br />

Timothy Yeatman, MD, FACS<br />

Professor of Surgery & Oncologic Sciences<br />

Executive Vice President and<br />

Founding Chief Scientific Officer<br />

Moffitt Medical Group<br />

Jonathan Zager, MD, FACS<br />

Assistant Professor of Surgery & Oncologic Sciences<br />

Cutaneous <strong>Oncology</strong> Program<br />

Sarcoma Program<br />

Jingsong Zhang, MD, PhD<br />

Assistant Professor of Medicine & Oncologic Sciences<br />

Genitourinary Program<br />

Experimental Therapeutics Program<br />

FACULTY DISCLOSURE | USF Health adheres to the<br />

ACCME Standards regarding commercial support of<br />

continuing medical education. It is the policy of USF<br />

Health and Moffitt Cancer Center that the faculty and<br />

planning committee disclose real or apparent conflicts<br />

of interest relating to the topics of this educational<br />

activity, that relevant conflict(s) of interest are<br />

resolved, and also that speakers will disclose any<br />

unlabeled/unapproved use of drug(s) or device(s)<br />

during their presentation. Detailed disclosure will be<br />

made in the course syllabus.<br />

The Ritz-Carlton, Naples offers dazzling views of the Gulf of Mexico, three miles of pristine beaches,<br />

world-class restaurants and impeccable service, The Ritz-Carlton in Naples, <strong>Florida</strong>, offers an<br />

unforgettable retreat in one of the world’s most beautiful locations.<br />

A block of rooms have been reserved for our conference for the special price of $209.00 single/double<br />

occupancy. Reserve your room by calling 1-888-856-4380 and reference the Moffitt Cancer Center<br />

conference or on the Reservations page of www.ritzcarlton.com by entering group code QNEQNEA.<br />

Reservations must be made on or before April 5, 2011.<br />

Check-in 4:00 pm; check-out 12 noon. Valet parking only for cost of $15 per night.<br />

__ 2/11


NON-PROFIT ORG<br />

US POSTAGE<br />

PAID<br />

TAMPA FL<br />

PERMIT NO 2849<br />

H. Lee Moffitt Cancer Center<br />

& Research Institute<br />

12902 Magnolia Drive<br />

Tampa, FL 33612-9416<br />

2nd ANNUAL<br />

<strong>Florida</strong> <strong>Oncology</strong> <strong>Symposium</strong>:<br />

Clinical Pathways to Personalized Medicine<br />

May 5 – 7, 2011<br />

The Ritz-Carlton Hotel<br />

Naples, <strong>Florida</strong>

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