Florida Oncology Symposium:
Florida Oncology Symposium:
Florida Oncology Symposium:
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2nd ANNUAL<br />
<strong>Florida</strong> <strong>Oncology</strong> <strong>Symposium</strong>:<br />
Clinical Pathways to Personalized Medicine<br />
May 5 – 7, 2011<br />
The Ritz-Carlton Hotel<br />
Naples, <strong>Florida</strong>
<strong>Florida</strong> <strong>Oncology</strong> <strong>Symposium</strong>:<br />
Clinical Pathways to Personalized Medicine<br />
May 5 – 7, 2011 The Ritz-Carlton Hotel | Naples, <strong>Florida</strong><br />
COURSE DESCRIPTION<br />
Our second symposium offers learning opportunities and<br />
networking for those clinicians wanting to learn more about<br />
the latest clinical research applications to patient care in the<br />
diagnosis and management of various cancers: Hematology,<br />
Genitourinary Cancers, Melanoma, HPV and Sarcoma.<br />
In addition, an update on the progress of Moffitt’s newly<br />
developed clinical pathways will be offered as a concurrent<br />
breakout session. These pathways have been developed to<br />
assist and to improve clinical outcomes in these disease sites:<br />
breast, prostate, lung, acute leukemia, sarcoma and pancreas.<br />
The objective is to catalyze clinician consensus and to reduce<br />
clinician variation toward the best possible outcome given<br />
a patient’s unique clinical factors, genetics, and personal<br />
preferences. These pathways are primarily designed to support<br />
the administration of therapies proven to optimize efficacy and<br />
reduce toxicity, and secondarily to manage cost when prudent<br />
choices between clinically similar alternatives can drive more<br />
affordable, quality care.<br />
We are proud to share<br />
the early progress<br />
toward clinical pathways<br />
development with the<br />
conference participants<br />
to achieve an even<br />
better product by<br />
incorporating related<br />
feedback and<br />
collaboration.<br />
TARGET AUDIENCE<br />
This educational activity<br />
is planned to meet the<br />
educational needs of<br />
clinical and surgical oncologists in both academia and private<br />
practice. Primary care physicians and nurses in oncology will<br />
benefit from the presentations and small group discussions in<br />
the latest cancer treatment modalities.<br />
PROGRAM OBJECTIVES<br />
Upon completion of this program, participants should<br />
be able to:<br />
• Discuss circulating tumor cells and how they can serve<br />
as a new platform to provide personalized medicine.<br />
• To tailor therapies for chronic leukemias.<br />
• Understand how HPV vaccination can be used to<br />
prevent different cancers in both women and men.<br />
• Assess the current role of robotic cystectomy in the<br />
management of localized bladder cancer.<br />
• Evaluate management options for prostate, bladder<br />
and kidney cancer.<br />
• Describe new drugs and targets that are important<br />
in early phase clinical trials.<br />
• Discuss the diagnosis and treatment of GIST,<br />
soft tissue and bone sarcomas.<br />
• Recognize how clinical pathways use a patient’s genetic<br />
signature to formulate personalized therapy.<br />
• Recognize the benefits of immunotherapy for<br />
melanoma and hematologic malignancies.<br />
ACCREDITATION<br />
Physicians USF Health is accredited by the Accreditation<br />
Council for Continuing Medical Education to provide continuing<br />
medical education for physicians.<br />
USF Health designates this educational activity for a maximum<br />
of 16.25 AMA PRA Category 1 Credits . Physicians should only<br />
claim credit commensurate with the extent of their participation<br />
in the activity.<br />
Nurses The University of South <strong>Florida</strong> College of Nursing<br />
is accredited as a provider of continuing nursing education<br />
by the American Nurses Credentialing Center’s Commission<br />
on Accreditation.<br />
A maximum of 16.25 contact hours may be earned by<br />
learners who successfully complete this continuing nursing<br />
education activity.
AGENDA<br />
MAY 5, 2011 | THURSDAY<br />
11:00 am – 7:00 pm Registration<br />
12:45 – 1:00 pm Welcome and Introduction<br />
Daniel Sullivan, MD<br />
1:00 – 3:00 pm Personalized Medicine:<br />
New and Exciting Molecular Platforms<br />
Chairperson: Timothy Yeatman, MD, FACS<br />
• Circulating Tumor Cells as a Guide to Personalized<br />
Medicine in Cancer — David Nelson, PhD<br />
• Integrating Biomarkers into Colorectal Cancer Clinical<br />
Trials — Scott Kopetz, MD, PhD<br />
• The “Next Generation” of Translational <strong>Oncology</strong> —<br />
Levi Garraway, MD, PhD<br />
3:00 – 3:15 pm Break<br />
3:15 – 5:15 pm Molecular Determinants of Response<br />
in Clinical <strong>Oncology</strong><br />
• Microarrays for Diagnosis, Prognosis and Treatment<br />
Planning of Breast Cancer — Stefan Glück, MD, PhD, FRCPC<br />
• Biomarkers That Determine Response in Multiple Myeloma<br />
and Non-Hodgkin’s Lymphoma — Steven Grant, MD<br />
• Biomarker-Driven Trials in Ovarian Cancer —<br />
Johnathan Lancaster, MD, PhD<br />
• Bio-marker Driven Trials in NSCLC — Scott Antonia, MD, PhD<br />
7:00 – 9:00 pm Dinner with Keynote speaker<br />
Molecular Signatures for Guiding Therapies of<br />
Non-Small Cell Lung Cancer<br />
David Carbone, MD, PhD<br />
MAY 6, 2011 | FRIDAY<br />
7:00 – 7:55 am Breakfast and Exhibits<br />
7:55 – 8:00 am Welcome and Introduction<br />
Alan List, MD, Course Director<br />
8:00 - 10:00 am SESSION 1: Hematology/<strong>Oncology</strong><br />
Chairperson: Eduardo Sotomayor, MD<br />
• AML in the Elderly: New Therapies — Jeffrey Lancet, MD<br />
• Consolidation therapy in AML: Should we transplant<br />
everyone? — Hugo Fernandez, MD<br />
• Targeted Therapies for Chronic Leukemias —<br />
Javier Pinilla-Ibarz, MD, PhD<br />
• Radioimmunotherapy for Hematologic Malignancies —<br />
Michael Tomblyn, MD<br />
10:00 – 10:30 am Break and Exhibits<br />
10:30 – 11:30 am SESSION 2: Prevention of HPV –<br />
Related Cancers: Current Practice and<br />
Future Horizons<br />
Chairperson: Dana Rollison, PhD<br />
• Cancer Prevention through HPV Vaccination in Men<br />
and Women — Kevin Collins, MD<br />
• Cutaneous HPV and Non-Melanoma Skin Cancer —<br />
Dana Rollison, PhD<br />
11:30 am – 12:45 pm Luncheon with Keynote Speaker<br />
Quality, Measurement and Economics of<br />
Health Care Systems<br />
Lisa Slama, PhD<br />
12:45 – 2:30 pm SESSION 3: Genitourinary Cancers<br />
Chairperson: Julio Pow-Sang, MD<br />
• Active Surveillance and Surgical Options for Localized<br />
Prostate Cancer — Julio Pow-Sang, MD<br />
• Radiation Therapy Options for Localized Prostate Cancer -<br />
Richard Wilder, MD<br />
(FRIDAY CONTINUED)<br />
• Treatment Options for Hormone Refractory Prostate<br />
Cancer — Jingsong Zhang, MD, PhD<br />
• Management Options for Small Renal Tumors —<br />
Philippe Spiess, MD<br />
• Emerging Role of Robotic Cystectomy in the Management<br />
of Invasive Bladder Cancer — Wade Sexton, MD<br />
2:30 - 4:30 pm SESSION 4: Moffitt Pathways<br />
Chairperson: Robert Wenham, MD<br />
2:30 – 3:00 pm Pathways to Improving Clinical Outcomes<br />
Mark Schippits, MD<br />
3:00 - 3:30 pm Break and Exhibits<br />
3:30 – 4:00 pm Break Out Sessions (select one)<br />
• Breast — Hatem Soliman, MD<br />
• Prostate — Mayer Fishman, MD, PhD and J. Zhang, MD, PhD<br />
• Lung — Mary Pinder, MD<br />
• Acute Leukemia — Jeffrey Lancet, MD<br />
• Sarcoma — Damon Reed, MD<br />
• Pancreatic — Gregory Springett, MD, PhD<br />
4:00 – 4:30 pm Break Out Sessions Repeated (select one)<br />
• Breast — Hatem Soliman, MD<br />
• Prostate — Mayer Fishman, MD, PhD and J. Zhang, MD, PhD<br />
• Lung — Mary Pinder, MD<br />
• Acute Leukemia — Jeffrey Lancet, MD<br />
• Sarcoma — Damon Reed, MD<br />
• Pancreatic — Gregory Springett, MD, PhD<br />
Evening on Your Own<br />
MAY 7, 2011 | SATURDAY<br />
7:00 – 8:00 am Breakfast<br />
8:00 – 9:30 am SESSION 5: Advances in the Treatment of<br />
Metastatic Melanoma<br />
Chairperson: Jeffrey Weber, MD, PhD<br />
• INTRODUCTION: Melanoma: Poster Child for Novel and<br />
Targeted Therapies — Jeffrey Weber, MD, PhD<br />
• Regional Treatment for Melanoma: Liver or Limb? —<br />
Jonathan Zager, MD<br />
• Targeted Therapy for Melanoma is Here At Last —<br />
Ragini Kudchadkar, MD<br />
• Novel Immunotherapies for Melanoma Prolong Survival —<br />
Jeffrey Weber, MD, PhD<br />
9:30 – 10:00 am Break and Exhibits<br />
10:00 – 11:30 am SESSION 6: Advances in Drug Development<br />
Chairperson: Saïd Sebti, MD, PhD<br />
• Targeting the Akt Pathway: From Basic Science to<br />
Hypothesis-driven Clinical Trials — Saïd Sebti, MD, PhD<br />
• Disruptors of the Binding of Raf1 Kinase to the<br />
Tumor Suppressor Rb as Novel Anticancer Drugs —<br />
Kumar Chellappan, MD<br />
• Targeting Shp2 Protein Phosphatase for Drug Discovery —<br />
Jerry Wu, MD<br />
11:30 am – 1:00 pm Lunch with Guest Speaker<br />
1:00 – 2:30 pm SESSION 7: Sarcoma<br />
Chairperson: Douglas Letson, MD<br />
• GIST — Updates and Future Direction — Rick Gonzalez, MD<br />
• Bone Sarcomas: What Have we Learned and Where are<br />
the Opportunities for Improvement? — Damon Reed, MD<br />
• Soft Tissue Sarcoma: Breaking Tradition —<br />
Anthony Conley, MD<br />
2:30 pm Closing Remarks/Conference Adjourns
Name ____________________________________________________________<br />
Degree/Credentials ________________________________________________<br />
Date of Birth (MM/DD) _________________ Specialty ________________<br />
License #__________________________________________________________<br />
Organization ______________________________________________________<br />
Address __________________________________________________________<br />
City________________________________ State_________ ZIP __________<br />
Phone________________________ Fax ________________________________<br />
E-mail ____________________________________________________________<br />
Attendance Thursday keynote dinner ❏ Yes ❏ No<br />
Attendance Saturday night dinner ❏ Yes ❏ No<br />
❏ Complimentary nurse registration accompanying physician<br />
Name ____________________________________________________________<br />
License #__________________________________________________________<br />
E-mail ____________________________________________________________<br />
FEES<br />
REGISTRATION FORM<br />
FLORIDA ONCOLOGY SYMPOSIUM<br />
May 5 – 7, 2011<br />
The Ritz-Carlton Hotel | Naples, <strong>Florida</strong><br />
REGISTRATION FEE INCLUDES:<br />
Conference materials and all meal functions during conference.<br />
Attendance Thursday keynote dinner ❏ Yes ❏ No<br />
Attendance Saturday night dinner ❏ Yes ❏ No<br />
Please place a check mark next to your registration type.<br />
❏ Physician ..............................................................................................$225.00<br />
❏ Physician Assistant ..................................................................$1 75.00<br />
❏ Nurse ............................................................................................$1 75.00<br />
❏ Other Health Care Professional ..............................................$150.00<br />
Dinner Guests<br />
❏ Thursday night dinner ................................................................$40.00<br />
# of guests _____<br />
❏ Saturday night reception and dinner ....................................$75.00<br />
# of guests _____<br />
❏ Children (7-14) Saturday dinner ............................................$25.00<br />
# of children _____<br />
TOTAL AMOUNT $______________<br />
On-line registration deadline May 2, 2011.<br />
On-site registration will be available.<br />
PAYMENT METHOD<br />
❏ Check (payable to Moffitt Cancer Center)<br />
❏ MasterCard ❏ Visa ❏ American Express ❏ Discover<br />
Amount $______________<br />
Credit Card # ______________________________________________________<br />
Expiration Date ____________________________________________________<br />
Cardholder Name __________________________________________________<br />
Signature ________________________________________________________<br />
REGISTRATION OPTIONS<br />
• On-line at www.moffitt.org/FOS2011<br />
• Paper Registration, please mail along with payment to:<br />
Moffitt Cancer Center<br />
MBC-CONFPLAN<br />
12902 Magnolia Drive<br />
Tampa, FL 33612-9497<br />
For further information, contact Melissa Pearson at 813-745-1247<br />
or Melissa.Pearson@moffitt.org<br />
REFUND POLICY: An administrative fee of $50.00 will be assessed for cancellations<br />
received on or before April 22, 2011 and no refunds will be issued after this date.<br />
Events, activities, programs and facilities of the University of South <strong>Florida</strong> are available<br />
to all without regard to race, color, marital status, gender, sexual orientation, religion,<br />
national origin, disability, age, Vietnam or disabled veteran status as provided by law<br />
and in accordance with the university’s respect for personal dignity.<br />
USF HPCC is an Equal Opportunity/Equal Access Institution. For disability accommodations<br />
contact USF HPCC at 813-974-7420, a minimum of five (5) working days in advance.<br />
Program # CH 2011401/1160
FACULTY<br />
COURSE DIRECTOR<br />
Alan List, MD<br />
Professor of Medicine & Oncologic Sciences<br />
Executive Vice President & Physician-in-Chief<br />
The Frank & Carol Morsani Endowed Chair<br />
Moffitt Cancer Center<br />
Tampa, <strong>Florida</strong><br />
Guest Faculty<br />
David Carbone, MD, PhD<br />
Professor of Medicine and Cancer Biology<br />
Vanderbilt University Cancer Center<br />
Nashville, Tennessee<br />
Kevin Collins, MD<br />
Director, Clinical Services<br />
Student Health<br />
<strong>Florida</strong> Gulf Coast University<br />
Fort Myers, <strong>Florida</strong><br />
Levi Garraway, MD, PhD<br />
Assistant Professor<br />
Department of Medical <strong>Oncology</strong><br />
Harvard Medical School<br />
Dana-Farber Cancer Institute<br />
Boston, Massachusetts<br />
Stefan Glück, MD, PhD, FRCPC<br />
Sylvester Professor, Department of Medicine<br />
University of Miami<br />
Leonard M. Miller School of Medicine<br />
Assistant Director, Associate Chief<br />
Division of Hematology/<strong>Oncology</strong><br />
Sylvester Comprehensive Cancer Center<br />
Miami, <strong>Florida</strong><br />
Steven Grant, MD<br />
Associate Director, Translational Research<br />
Co-Director, Cancer Cell Biology Program<br />
Virginia Commonwealth University<br />
Massey Cancer Center<br />
Richmond, Virginia<br />
Scott Kopetz, MD, PhD<br />
Assistant Professor<br />
GI Medical <strong>Oncology</strong><br />
University of Texas<br />
M.D. Anderson Cancer Center<br />
Houston, Texas<br />
David Nelson, PhD<br />
President and CEO<br />
Epic Sciences<br />
San Diego, California<br />
Lisa Slama, PhD<br />
Associate Vice President<br />
Sg2<br />
Skokie, Illinois<br />
ACCOMMODATIONS<br />
THE RITZ-CARLTON NAPLES<br />
280 Vanderbilt Beach Road<br />
Naples, <strong>Florida</strong> 34108<br />
239-598-3300<br />
www.ritzcarlton.com<br />
USF Health Faculty<br />
at Moffitt Cancer Center<br />
Scott Antonia, MD, PhD<br />
Professor of Oncologic Sciences<br />
Chairman, Thoracic <strong>Oncology</strong> Department<br />
Co-Leader, Immunology Program<br />
Srikumar Chellappan, PhD<br />
Professor of Molecular Medicine & Oncologic Sciences<br />
Professor & Chair, Department of Tumor Biology<br />
Scientific Director, National Functional Genomics Center<br />
Anthony Conley, MD<br />
Assistant Professor of Oncologic Sciences<br />
Sarcoma Program<br />
Hugo Fernandez, MD<br />
Professor of Medicine & Oncologic Sciences<br />
Associate Chair & Clinical Director<br />
Department of Blood & Marrow Transplantation<br />
Mayer Fishman, MD, PhD<br />
Associate Professor of Medicine & Oncologic Sciences<br />
Genitourinary <strong>Oncology</strong><br />
Experimental Therapeutics Program<br />
Ricardo Gonzalez, MD<br />
Assistant Professor of Oncologic Sciences<br />
Surgical Oncologist, Sarcoma Program<br />
& Cutaneous <strong>Oncology</strong><br />
Ragini Kudchadkar, MD<br />
Assistant Professor of Medicine & Oncologic Sciences<br />
Cutaneous <strong>Oncology</strong> Program<br />
Johnathan Lancaster, MD, PhD<br />
Associate Professor, Department of Oncologic Sciences<br />
Chair, Department of Women’s <strong>Oncology</strong><br />
Director, Center for Women's <strong>Oncology</strong><br />
Jeffrey Lancet, MD<br />
Associate Professor of Medicine & Oncologic Sciences<br />
Section Head, Leukemia<br />
Department of Malignant Hematology<br />
Douglas Letson, MD<br />
Professor of Radiology, Orthopaedic <strong>Oncology</strong> & Surgery<br />
Division Chair, Sarcoma Program<br />
Mary Pinder-Schneck, MD<br />
Assistant Professor of Medicine & Oncologic Sciences<br />
Medical <strong>Oncology</strong><br />
Thoracic <strong>Oncology</strong> Program<br />
Javier Pinilla-Ibarz, MD, PhD<br />
Assistant Professor of Medicine & Oncologic Sciences<br />
Department of Malignant Hematology<br />
Julio Pow-Sang, MD<br />
Professor of Surgery & Oncologic Sciences<br />
Chief, Surgery Services<br />
Director, Robotics Program<br />
Department of GU <strong>Oncology</strong><br />
Damon Reed, MD<br />
Assistant Professor of Medicine & Oncologic Sciences<br />
Medical Oncologist, Sarcoma Program<br />
Dana Rollison, PhD<br />
VP/Chief, of Health Informatics<br />
Associate Professor of Oncologic Sciences<br />
Scientific Director, Moffitt Cancer Registry<br />
Co-Scientific Director, Moffitt Tissue Core<br />
Mark Schippits, MD<br />
Director, Clinical Informatics Program<br />
Saïd Sebti, PhD<br />
Professor of Molecular Medicine & Oncologic Sciences<br />
Garcia Endowed Professor & Chair<br />
Director, Drug Discovery Comprehensive<br />
Research Center<br />
Department of Drug Discovery<br />
Wade Sexton, MD<br />
Associate Professor of Oncologic Sciences<br />
Genitourinary Program<br />
Fellowship Director<br />
Hatem Soliman, MD<br />
Assistant Professor of Medicine & Oncologic Sciences<br />
Comprehensive Breast Program<br />
Department of Women’s <strong>Oncology</strong><br />
Eduardo Sotomayor, MD<br />
Professor of Medicine & Oncologic Sciences<br />
Susan and John Sykes Endowed Chair in Malignant<br />
Hematology<br />
Department of Malignant Hematology<br />
Phillip Spiess, MD<br />
Assistant Professor of Oncologic Sciences<br />
Genitourinary <strong>Oncology</strong> & Urology<br />
Gregory Springett, MD, PhD<br />
Assistant Professor of Medicine & Oncologic Sciences<br />
Department of Gastrointestinal <strong>Oncology</strong><br />
Section of Pancreatic <strong>Oncology</strong><br />
Experimental Therapeutics & Drug Discovery Department<br />
Daniel Sullivan, MD<br />
Professor of Medicine,<br />
Molecular Medicine& Oncologic Sciences<br />
Executive Vice President & Associate<br />
Center Director for Clinical Investigations<br />
Leader, Phase I Program<br />
Blood & Marrow Transplantation Department<br />
Michael Tomblyn, MD, MS<br />
Assistant Professor of Medicine & Oncologic Sciences,<br />
Department of Radiation <strong>Oncology</strong><br />
Jeffrey Weber, MD, PhD<br />
Professor of Medicine & Oncologic Sciences<br />
Director, Donald A. Adam Comprehensive<br />
Melanoma Research Center<br />
H. LEE MOFFITT CANCER CENTER & RESEARCH INSTITUTE, AN NCI COMPREHENSIVE CANCER CENTER - TAMPA, FL. 1-888-MOFFITT<br />
© 2011 H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. All rights reserved.<br />
Robert Wenham, MD, MS, FACOG<br />
Assistant Professor of Oncologic Sciences<br />
Clinical Director, Gynecologic <strong>Oncology</strong> Medical Director,<br />
Moffitt Clinical Research Network<br />
Principal Investigator,<br />
Total Cancer Care Department of Women's <strong>Oncology</strong><br />
Richard Wilder, MD, MBA, MS<br />
Associate Professor of Radiology & Oncologic Sciences<br />
Radiation <strong>Oncology</strong>/Genitourinary <strong>Oncology</strong><br />
Department of Radiation <strong>Oncology</strong><br />
Jie Wu, PhD<br />
Professor of Molecular Medicine & Oncologic Sciences<br />
Department of Molecular <strong>Oncology</strong><br />
Timothy Yeatman, MD, FACS<br />
Professor of Surgery & Oncologic Sciences<br />
Executive Vice President and<br />
Founding Chief Scientific Officer<br />
Moffitt Medical Group<br />
Jonathan Zager, MD, FACS<br />
Assistant Professor of Surgery & Oncologic Sciences<br />
Cutaneous <strong>Oncology</strong> Program<br />
Sarcoma Program<br />
Jingsong Zhang, MD, PhD<br />
Assistant Professor of Medicine & Oncologic Sciences<br />
Genitourinary Program<br />
Experimental Therapeutics Program<br />
FACULTY DISCLOSURE | USF Health adheres to the<br />
ACCME Standards regarding commercial support of<br />
continuing medical education. It is the policy of USF<br />
Health and Moffitt Cancer Center that the faculty and<br />
planning committee disclose real or apparent conflicts<br />
of interest relating to the topics of this educational<br />
activity, that relevant conflict(s) of interest are<br />
resolved, and also that speakers will disclose any<br />
unlabeled/unapproved use of drug(s) or device(s)<br />
during their presentation. Detailed disclosure will be<br />
made in the course syllabus.<br />
The Ritz-Carlton, Naples offers dazzling views of the Gulf of Mexico, three miles of pristine beaches,<br />
world-class restaurants and impeccable service, The Ritz-Carlton in Naples, <strong>Florida</strong>, offers an<br />
unforgettable retreat in one of the world’s most beautiful locations.<br />
A block of rooms have been reserved for our conference for the special price of $209.00 single/double<br />
occupancy. Reserve your room by calling 1-888-856-4380 and reference the Moffitt Cancer Center<br />
conference or on the Reservations page of www.ritzcarlton.com by entering group code QNEQNEA.<br />
Reservations must be made on or before April 5, 2011.<br />
Check-in 4:00 pm; check-out 12 noon. Valet parking only for cost of $15 per night.<br />
__ 2/11
NON-PROFIT ORG<br />
US POSTAGE<br />
PAID<br />
TAMPA FL<br />
PERMIT NO 2849<br />
H. Lee Moffitt Cancer Center<br />
& Research Institute<br />
12902 Magnolia Drive<br />
Tampa, FL 33612-9416<br />
2nd ANNUAL<br />
<strong>Florida</strong> <strong>Oncology</strong> <strong>Symposium</strong>:<br />
Clinical Pathways to Personalized Medicine<br />
May 5 – 7, 2011<br />
The Ritz-Carlton Hotel<br />
Naples, <strong>Florida</strong>