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Biotechnology, Pest Management, and the Environment: The Future 509<br />

develop and standardize technology to detect such foods (Holst-Jensen, 2006). In addition,<br />

a requirement to label approved genetically modifi ed food would necessitate a constant<br />

monitoring system, and the cost of such monitoring will be formidable for many developing<br />

countries. This will also take precious resources away from their main agenda of using<br />

science for development. Future research efforts in this area should focus on:<br />

• Biosafety regulations based on safety, quality, and effi cacy;<br />

• Expanding procedures to assess allergy to encompass inhalants as well as allergy<br />

to food;<br />

• Establishment of reliable methods for detection and quantifi cation of genetically<br />

modifi ed food; and<br />

• Address the issue of food labeling in the unorganized sector, and ensure food<br />

safety at the testing stage.<br />

Conclusions<br />

The products of biotechnology should be commercially viable, environmentally benign,<br />

easy to use in diverse agroecosystems, and have a wide spectrum of activity against the target<br />

insect pests, but be harmless to nontarget organisms. There is a need to pursue a management<br />

strategy that takes into account the insect biology, insect plant interactions, and their<br />

infl uence on the natural enemies. Emphasis should be placed on combining exotic genes<br />

with conventional host plant resistance, and also with traits conferring resistance to other<br />

insect pests and diseases of importance in the target region. It is important to follow the<br />

biosafety regulations and make this technology available to farmers who cannot afford the<br />

high cost of seeds and chemical pesticides. Use of biotechnological tools for diagnosis of<br />

insect pests and their natural enemies, and for gaining an understanding of their population<br />

genetics, behavior, and interactions with the host plant will provide a sound foundation<br />

for pest management. There is a need to use genetic engineering to produce robust natural<br />

enemies, and more stable and virulent strains of entomopathogenic bacteria, fungi, viruses,<br />

protozoa, and nematodes for use in integrated pest management. Molecular makers can be<br />

used for development of newer pesticide molecules with different modes of action, and<br />

monitoring insect resistance to insecticides. Augmentation of conventional breeding with<br />

the use of marker-assisted selection and transgenic plants promises to facilitate substantial<br />

increases in food production. Rapid and cost-effective development and adoption of biotechnology-derived<br />

products will depend on developing a full understanding of the interaction<br />

of genes within their genomic environment, and with the environment in which<br />

their conferred phenotype must interact for sustainable crop protection.<br />

References<br />

Atkinson, P.W. and O’Brochta, D.A. (1999). Genetic transformation of non-drosophilid insects by<br />

transposable elements. Annals of the Entomological Society of America 92: 930–936.<br />

Barton, K.A. and Miller, M.J. (1991). Insecticidal toxins in plants. EPA 0431829 A1 910612.

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