The Structure of the Cell Membrane Resting Membrane Potential

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Lipid bilayer • twice as much lipid in the membrane of the red blood cells than needed for a monolayer → lipid bilayer Polar heads toward the intra- and extracellular space EC IC Gortel, E. & Grendel, F. (1925) On bimolecular layers of lipoid on the chromocytes of the blood. J. Exp. Med. 41, 439–443. Apolar tails in the middle
• phospho-lipid bilayer „Fluid mosaic” model • 1972 - Singer and Nicholson „fluid mosaic” model • Fluid – lateral movement of the components („floating”) • Mosaic – the mosaic-like arrangement of the macromolecules http://www.molecularexpressions.com/cells/plasmamembrane/plasmamembrane.html Singer SJ, Nicolson GL. The fluid mosaic model of the structure of cell membranes. Science. 1972 Feb 18;175(23):720-31.
Page 1 and 2: The Structure of the Cell Membrane
Page 3 and 4: Irving Langmuir 1881 - 1957 America
Page 8 and 9: Structure of the cell membrane Flip
Page 10 and 11: The main components of the intra- a
Page 12 and 13: Ionic concentrations inside and out
Page 14 and 15: Electrical potential ● Electric p
Page 16 and 17: Bernstein’s potassium hypothesis
Page 18 and 19: Bernstein’s potassium hypothesis
Page 20 and 21: Walther Hermann Nernst German physi
Page 22 and 23: Equlibrium (resting) condition NzFE
Page 24 and 25: Nernst equation E = RT zF ln X −
Page 26 and 27: What happens if the cell membrane i
Page 29 and 30: Donnan rule of equilibrium • Diff
Page 31 and 32: Goldman-Hodgkin-Katz Constant field
Page 33 and 34: Goldman equation The membrane poten

The Structure of the Cell Membrane Resting Membrane Potential

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