The Structure of the Cell Membrane Resting Membrane Potential

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Phospholipids The main component of the biological membranes. Phospholipid = diglyceride (glycerine+fatty acid) + phosphate group + organic molecule (e.g. choline). „water soluble fat” Polar – head (hydrophilic) Non-polar – tail (hydrophobic) phosphatidil - cholin
Irving Langmuir 1881 - 1957 American physico-chemist 1932 Nobel-price in chemistry • 1917 – lipids form a monolayer on the surface of the water polar heads (hydrophilic) – oriented toward the water nonpolar tails (hydrophobic) – oriented away from water Irving Langmuir, "The Constitution and Fundamental Properties of Solids and Liquids. II," Journal of the American Chemical Society 39 (1917): 1848-1906. water
Page 1: The Structure of the Cell Membrane
Page 6 and 7: Lipid bilayer • twice as much lip
Page 8 and 9: Structure of the cell membrane Flip
Page 10 and 11: The main components of the intra- a
Page 12 and 13: Ionic concentrations inside and out
Page 14 and 15: Electrical potential ● Electric p
Page 16 and 17: Bernstein’s potassium hypothesis
Page 18 and 19: Bernstein’s potassium hypothesis
Page 20 and 21: Walther Hermann Nernst German physi
Page 22 and 23: Equlibrium (resting) condition NzFE
Page 24 and 25: Nernst equation E = RT zF ln X −
Page 26 and 27: What happens if the cell membrane i
Page 29 and 30: Donnan rule of equilibrium • Diff
Page 31 and 32: Goldman-Hodgkin-Katz Constant field
Page 33 and 34: Goldman equation The membrane poten

The Structure of the Cell Membrane Resting Membrane Potential

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