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CIP System Troubleshooting Guide 311<br />

The first point of investigation when there is acycling high- and low-level<br />

condition on aqualified CIP circuit is confirmation of the level sensor calibration.<br />

CIP skid level sensors are prone to drift due to the widely varying temperatures<br />

they may be exposed to during the cleaning process. If the level sensor has been<br />

found to be properly calibrated, then aFEinvestigation may be in order; aFEout of<br />

calibration on the high end may overfill the CIP circuit, resulting in circuit<br />

recirculation instability. The troubleshooter must review the process equipment<br />

evaluate the CIP return conditions per previously presented methods to determine<br />

the cause for the temporary process vessel solution hold up.<br />

Recirculation Tank Low Level<br />

When the CIP recirculation Tank reaches low level, common practice is to open the<br />

water supply valve to charge acontrolled volume of water into the CIP circuit to<br />

assist in bringing the CIP skid recirculation tank up to operating level again. If after<br />

the water addition, the tank is not within normal operating range, the water<br />

addition may be repeated a fixed number of times to achieve circuit stability<br />

during recirculation.<br />

An unexpected loss of solution volume can result in alow-level condition at<br />

the CIP unit recirculating tank. This loss may be from aleaky U-Bend at atransfer<br />

panel, apoorly fitted supply hose connection, or an open manual low point drain<br />

valve. The key indicators for an unmonitored solution loss include the CIP skid<br />

recirculation tank is at low level, no rising level is observed the vessel being cleaned,<br />

one or more water additions are required to maintain circuit recirculation, and CIP<br />

Supply flow controland pressure levels may be low during the low-level excursion.<br />

Impact of Water Addition<br />

Awater add action can assist in restoring circuit hydraulic stability. However, the<br />

water addition may have the following negative effects if this action is performed in<br />

excess:<br />

& Reduction of cleaning chemical concentration<br />

& Potential impact on CIP circuit temperature<br />

& If low level is not due to circuit volume loss, may eventually result in a<br />

recirculation tank high-level condition and corrective action, or overflow.<br />

It should be understood that software fixes, i.e., high- and low-level control<br />

actions, are not the ideal approach to balancing CIP circuits. Proper engineering<br />

design can assure proper circuit balance and make these hard to manage, and<br />

troubleshoot, functions unnecessary.<br />

INADEQUATE FINAL RINSE<br />

This section assumes that the piping installation has adhered to American Society of<br />

Mechanical Engineering Bioprocessing Equipment (ASME BPE) recommendations<br />

to keep process/CIP piping dead-legs less than two pipe diameters, and horizontal<br />

in position. It is also assumed that water of proper quality is being supplied for rinse<br />

purposes. The more common causes to be investigated are poorly performing CIP<br />

supply air blow and drain operations before the final rinse, instrument calibration,<br />

poor CIP return flow, and process vessel puddling.

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