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Physiologic and Supraphysiologic Increases in Lipoprotein Lipids ...

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412 ARTERIOSCLEROSIS VOL 4, No 4, JULY/AUGUST 1984<br />

Table 4. Hypertrlglycerldemla In Pregnancy: Subject D.R.<br />

Pregnant<br />

Week 36<br />

Week 6<br />

Whole plasma (mg/dl)<br />

Triglyceride<br />

Cholesterol<br />

VLDL (mg/dl)<br />

Triglyceride<br />

Cholesterol<br />

Apo B<br />

LDL (mg/dl)<br />

Triglyceride<br />

Cholesterol<br />

Apo B<br />

HDL (mg/dl)<br />

Triglyceride<br />

Cholesterol<br />

Apo A-1<br />

600<br />

329<br />

382<br />

79<br />

44<br />

164<br />

240<br />

181<br />

10<br />

14<br />

158<br />

(387)*<br />

(318)<br />

(246)<br />

(47)<br />

(113)<br />

(218)<br />

121<br />

(21)<br />

(42)<br />

95<br />

211<br />

169<br />

131<br />

23<br />

9<br />

34<br />

114<br />

99<br />

7<br />

12<br />

95<br />

(157)*<br />

(265)<br />

(122)<br />

(29)<br />

(36)<br />

(177)<br />

(4)<br />

(44)<br />

Postpartum<br />

Week 20<br />

102<br />

163<br />

69<br />

15<br />

7<br />

24<br />

109<br />

6<br />

36<br />

116<br />

(127)*<br />

(225)<br />

(83)<br />

(28)<br />

(35)<br />

(157)<br />

(5)<br />

(35)<br />

Week 40<br />

115<br />

154<br />

71<br />

17<br />

25<br />

97<br />

15<br />

40<br />

(127)*<br />

(225)<br />

(83)<br />

(28)<br />

(35)<br />

(157)<br />

D.R.'s <strong>in</strong>fant's birth weight was 3239 g. D.R. elected not to breast feed postpartum or use oral<br />

contraceptives. See text for family study lipids.<br />

'Denotes 95th percentiles for total, VLDL, <strong>and</strong> LDL lipids <strong>and</strong> 5th percentile for HDL lipids. Values for<br />

36 weeks of gestation <strong>and</strong> 6 weeks postpartum are based on a study of 553 pregnant women (see<br />

reference 5); values are from reference 6 for 20- to 29-year-old nonpregnant, nonhormone-tak<strong>in</strong>g subjects<br />

(Weeks 20 <strong>and</strong> 40).<br />

Table 5. Summary of Endogenous Hypertrlglycerldemic Subjects Studied In Pregnancy<br />

Pre-<br />

Pregnant<br />

Postpartum<br />

pregnant Week 36 Week 6 20 40 100<br />

Total triglyceride (mg/dl)<br />

(95th percentile)<br />

D.R.<br />

F.S.<br />

Y.F.<br />

C.B.<br />

Total cholesterol (mg/dl)<br />

(95th percentile)<br />

D.R.<br />

F.S.<br />

Y.F.<br />

C.B.<br />

LDL cholesterol (mg/dl)<br />

(95th percentile)<br />

D.R.<br />

F.S.<br />

Y.F.<br />

C.B.<br />

HDL cholesterol (mg/dl)<br />

(95th percentile)<br />

D.R.<br />

F.S.<br />

Y.F.<br />

C.B.<br />

(127)*<br />

—<br />

—<br />

—<br />

116<br />

(225)<br />

—<br />

—<br />

—<br />

223<br />

(157)<br />

—<br />

—<br />

160<br />

(35)<br />

—<br />

—<br />

40<br />

(387)t<br />

600<br />

434<br />

716<br />

1195<br />

(318)<br />

329<br />

184<br />

257<br />

274<br />

(218)<br />

240<br />

70<br />

60<br />

61<br />

(42)<br />

14<br />

40<br />

43<br />

38<br />

(157)t<br />

211<br />

179<br />

221<br />

392<br />

(265)<br />

169<br />

212<br />

267<br />

260<br />

(177)<br />

114<br />

152<br />

187<br />

163<br />

(44)<br />

12<br />

34<br />

36<br />

36<br />

(127)*<br />

102<br />

124<br />

151<br />

—<br />

(225)<br />

163<br />

169<br />

205<br />

—<br />

(157)<br />

109<br />

124<br />

124<br />

—<br />

(35)<br />

36<br />

29<br />

32<br />

—<br />

(127)*<br />

115<br />

—<br />

—<br />

570<br />

(225)<br />

154<br />

—<br />

—<br />

232<br />

(157)<br />

97<br />

—<br />

—<br />

—<br />

*Percentiles from a population of nonpregnant subjects (see reference 6).<br />

tPercentiles from a population study of pregnant <strong>and</strong> postpartum subjects (see reference 5).<br />

Downloaded from<br />

http://atvb.ahajournals.org/ by guest on June 29, 2013<br />

(35)<br />

40<br />

—<br />

—<br />

34<br />

(5)<br />

(35)<br />

(127)*<br />

—<br />

—<br />

—<br />

173<br />

(225)<br />

—<br />

—<br />

—<br />

213<br />

(157)<br />

—<br />

—<br />

—<br />

139<br />

(35)<br />

—<br />

—<br />

—<br />

39

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