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HARVEST [29,30] is a more complicated, but conceptually sound approach to access distributed<br />

<strong>in</strong><strong>format</strong>ion. It does not only use full text retrieval but also offers meta tags for structured<br />

<strong>in</strong><strong>format</strong>ion. It operates completely different to robots. The idea is not to search Web servers,<br />

but to rely on the <strong>in</strong><strong>format</strong>ion given by them us<strong>in</strong>g gatherers and brokers. Gatherers collect<br />

<strong>in</strong><strong>format</strong>ion about the specified documents on a specified server. They do not only <strong>in</strong>dex<br />

HTML documents but also postscript, w<strong>in</strong>word, rich text <strong>format</strong>, word perfect, framemaker,<br />

etc. For each document, data is stored <strong>in</strong> the so called Summary Object Interchange Format<br />

(SOIF). Brokers get <strong>in</strong><strong>format</strong>ion of gatherers and other brokers accord<strong>in</strong>g to def<strong>in</strong>ed rules.<br />

Further, brokers offer the searchable data to users.<br />

5 Case study: DOIA<br />

As diagnosis <strong>in</strong> Dermatology relies heavily on visual <strong>in</strong><strong>format</strong>ion we decided to set up an image<br />

database, a part of which is now offered through the WWW: Dermatology Onl<strong>in</strong>e Atlas<br />

(DOIA) [31-39]. DOIA is <strong>in</strong>tended to be a basis for a distributed hypermedia textbook of dermatology.<br />

It offers selected images from our slide archive with about 100.000 slides. Right<br />

now it covers basic diagnoses important for student education and an extensive collection of<br />

images from specialists <strong>in</strong> our hospital. DOIA shall become a distributed resource for reference<br />

and teach<strong>in</strong>g of outstand<strong>in</strong>g quality. With experts around the globe contribut<strong>in</strong>g, it will offer up<br />

to date images and expert knowledge.<br />

Some goals will be achieved through the common image atlas. Images will be stored <strong>in</strong> a standardized<br />

manner and a common language of description will be developed. In Dermatology<br />

there is already a very clear description language available, however, dermatologists tend to<br />

<strong>in</strong>vent new terms for description and the terms used are not really standardized. Giv<strong>in</strong>g a term<strong>in</strong>ology<br />

together with reference images may help here. Fast access will be available. It is still<br />

quite common to search for literature <strong>in</strong> Medl<strong>in</strong>e and order the papers. Rare and country specific<br />

diseases will be covered as specialists around the world will be asked to contribute to this<br />

resource. Even more important is that images of different sk<strong>in</strong> types (white, black, asian) will<br />

be available for reference. Sk<strong>in</strong> diseases tend to look completely different on different sk<strong>in</strong><br />

types and reference images are usually only available for the most common sk<strong>in</strong> type, e.g.<br />

white <strong>in</strong> Germany. An <strong>in</strong>ternational reference atlas will help <strong>in</strong> diagnosis.<br />

5.1 Images<br />

Cl<strong>in</strong>ical and histological images were selected from the archive or cont<strong>in</strong>u<strong>in</strong>g medical education<br />

(CME) units. These were commercially scanned and stored on PCDs, sometime we also<br />

used a slide scanner. Us<strong>in</strong>g a PC Pentium 100 with a miro 40sv graphics card and a miro<br />

2085E monitor plus miro proof for calibration, the images were enhanced and made anonymous.<br />

After manipulation the images and correspond<strong>in</strong>g thumbnails were stored on a magnetooptical<br />

disc and JPEG compressed on hard disc.<br />

Studies [40-43] with cl<strong>in</strong>ical photographs (sk<strong>in</strong>, body overview, etc.) have shown that the<br />

resolution of 768x512x24 (1.125MB) is sufficient to see every required detail. Further, it displays<br />

well on most screens, because usual monitor resolutions currently range from 800x600 to<br />

1600x1200. Another study [40] has shown that images at this resolution can be compressed at<br />

about 1:37 with JPEG without loos<strong>in</strong>g diagnostic relevant details. In about 90% of the images<br />

not even any difference could be detected between the orig<strong>in</strong>al and the compressed one.<br />

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