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Voie d'immunisation et séquence d'administration de l ... - TEL

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tel-00827710, version 1 - 29 May 2013<br />

Figure 43. Poly I:C induces rapid DC maturation. C57BL/6 mice were injected i.v. with 100µg of<br />

poly I:C. At the indicated time points, the spleen and a lymph no<strong>de</strong> were harvested. The total number<br />

of CD8α + DCs and CD103 + DCs per organ (A) and the expression of CD86 and IA b /IE b (B) were<br />

d<strong>et</strong>ermined. In (B) the gray histograms indicate the level of expression in untreated animals and the<br />

black line correspons to poly I:C-injected mice.<br />

124

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