Alaska Tuberculosis Program Manual - Epidemiology - State of Alaska
Alaska Tuberculosis Program Manual - Epidemiology - State of Alaska Alaska Tuberculosis Program Manual - Epidemiology - State of Alaska
Case Finding Identifying Suspected Tuberculosis Cases Most tuberculosis (TB) cases are detected during the medical evaluation of symptomatic illnesses. Persons experiencing symptoms ultimately attributable to TB usually seek care not at a public health TB clinic but rather from other medical practitioners in other healthcare settings. 10 Professionals in the primary healthcare sector, including hospital and emergency department clinicians, should be trained to recognize patients with symptoms consistent with TB. 11 Be alert for cases of TB among: o Persons who are contacts of patients with pulmonary TB o Persons with newly diagnosed infection with Mycobacterium tuberculosis (sometimes referred to at TB skin test converters). Screening for TB disease is especially important for: 12 o Immigrants and refugees with Class B1 or Class B2 TB notification status See B Notifications section 4.1. o Persons involved in TB outbreaks, and occasionally in working with populations with a known high incidence of TB. o When the risk for TB in the population is high and o Persons in jails, prisons, and other congregate facilities. The clinical presentation of TB varies considerably as a result of the extent of the disease and the patient’s response. TB should be suspected in any patient who has a persistent cough for more than two to three weeks, or other compatible signs and symptoms. 13 Note that these symptoms should suggest a diagnosis of TB but are not required. TB should be considered a diagnosis in asymptomatic patients with chest radiographs compatible with TB. A L A S K A T U B E R C U L O S I S P R O G R A M M A N U A L Diagnosis of Tuber culosis Disease 5.7 R e v i s e d N o v e m b e r 2 0 1 2
Table 3: WHEN TO SUSPECT PULMONARY TUBERCULOSIS IN ADULTS 14 Historic Features Exposure to a person with infectious tuberculosis (TB) Signs and Symptoms Typical of TB Chest Radiograph: Immunocompetent patients Chest Radiograph: Children and patients with advanced HIV infection Positive test result for Mycobacterium tuberculosis infection Presence of risk factors, such as immigration from a high-prevalence area, human immunodeficiency virus (HIV) infection, homelessness, or previous incarceration* Diagnosis of community-acquired pneumonia that has not improved after 7 days of treatment †,15 Prolonged coughing (≥2–3 weeks) with or without production of sputum that might be bloody (hemoptysis) §,16 Chest pain 17 Chills 18 Fever Night sweats Loss of appetite 19 Weight loss Weakness or easy fatigability 20 Malaise (a feeling of general discomfort or illness) 21 Classic findings of TB are upper-lobe opacities, frequently with evidence of contraction fibrosis and cavitation Lower-lobe and multilobar opacities, hilar adenopathy, or interstitial opacities might indicate TB * See Table 2: Persons at High Risk for Tuberculosis Infection and Progression to Tuberculosis Disease. † Patients treated with levofloxacin or moxifloxacin may have a clinical response when TB is the cause of the pneumonia. § Do not wait until sputum is bloody to consider a productive cough a symptom of TB. Sputum produced by coughing does not need to be bloody to be a symptom of TB. These features are not specific for TB, and, for every person in whom pulmonary TB is diagnosed, estimated 10–100 persons are suspected on the basis of clinical criteria and must be evaluated. Source: Adapted from: ATS, CDC, IDSA. Controlling tuberculosis in the United States: recommendations from the American Thoracic Society, CDC, and the Infectious Diseases Society of America. MMWR 2005;54(No. RR-12):33. Extrapulmonary Tuberculosis If a patient has a positive tuberculin skin test or interferon gamma release assay (IGRA), consider signs and symptoms of extrapulmonary TB. A L A S K A T U B E R C U L O S I S P R O G R A M M A N U A L Diagnosis of Tuber culosis Disease 5.8 R e v i s e d N o v e m b e r 2 0 1 2
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Case Finding<br />
Identifying Suspected <strong>Tuberculosis</strong> Cases<br />
Most tuberculosis (TB) cases are detected during the medical evaluation <strong>of</strong> symptomatic<br />
illnesses. Persons experiencing symptoms ultimately attributable to TB usually seek care<br />
not at a public health TB clinic but rather from other medical practitioners in other<br />
healthcare settings. 10 Pr<strong>of</strong>essionals in the primary healthcare sector, including hospital<br />
and emergency department clinicians, should be trained to recognize patients with<br />
symptoms consistent with TB. 11<br />
Be alert for cases <strong>of</strong> TB among:<br />
o Persons who are contacts <strong>of</strong> patients with pulmonary TB<br />
o Persons with newly diagnosed infection with Mycobacterium tuberculosis<br />
(sometimes referred to at TB skin test converters).<br />
Screening for TB disease is especially important for: 12<br />
o Immigrants and refugees with Class B1 or Class B2 TB notification status<br />
See B Notifications section 4.1.<br />
o Persons involved in TB outbreaks, and occasionally in working with<br />
populations with a known high incidence <strong>of</strong> TB.<br />
o When the risk for TB in the population is high and<br />
o Persons in jails, prisons, and other congregate facilities.<br />
The clinical presentation <strong>of</strong> TB varies considerably as a result <strong>of</strong> the extent <strong>of</strong> the<br />
disease and the patient’s response. TB should be suspected in any patient who has a<br />
persistent cough for more than two to three weeks, or other compatible signs and<br />
symptoms. 13<br />
Note that these symptoms should suggest a diagnosis <strong>of</strong> TB but are not required. TB<br />
should be considered a diagnosis in asymptomatic patients with chest radiographs<br />
compatible with TB.<br />
A L A S K A T U B E R C U L O S I S P R O G R A M M A N U A L Diagnosis <strong>of</strong> Tuber culosis Disease 5.7<br />
R e v i s e d N o v e m b e r 2 0 1 2