Alaska Tuberculosis Program Manual - Epidemiology - State of Alaska
Alaska Tuberculosis Program Manual - Epidemiology - State of Alaska Alaska Tuberculosis Program Manual - Epidemiology - State of Alaska
Laboratory Contact Information To locate and contact a laboratory, refer to Table 1: Laboratory Contact Information. For the list of the tests performed at each laboratory, refer to Table 2: Available Laboratory Tests. Table 1: LABORATORY CONTACT INFORMATION Roles and Responsibilities Contact Information State Laboratory Receives and performs primary specimen AFB concentrated smear and culture testing for mycobacteria Susceptibility testing of first-line drugs on Mycobacterium tuberculosis complex isolates Private Laboratories Non-tuberculosis mycobacterium susceptibility testing Confirmation of first-line drug testing on Mycobacterium tuberculosis complex isolates Second-line drug testing on Mycobacterium tuberculosis complex isolates Alaska State Public Health Laboratory (ASPHL) Mycobacteriology Laboratory 5455 Martin Luther King Jr Ave. P.O. Box 196093 Anchorage, AK 99507 Tel: (907) 334-2100 Fax: (907) 334-2161 National Jewish Health Mycobacteriology Reference Laboratory 1400 Jackson St. Denver, CO 80206 Tel: (303) 398-1339 Fax: (303) 398-1953 A L A S K A T U B E R C U L O S I S P R O G R A M M A N U A L Laborator y Services 12.3 Revised November 2012
Available Laboratory Tests Table 2: LABORATORY TESTS AVAILABLE IN ALASKA Test Laboratory Turnaround Time Diagnosis Acid-fast bacilli (AFB) smear (fluorochrome) Alaska State Public Health Laboratory Culture Alaska State Public Health Laboratory Drug susceptibility (first-line drugs only) Nucleic acid amplification (NAA) test Please see NAAT section 12.5 QuantiFERON ® -TB Gold In-Tube (QFT-GIT) Epidemiologic Monitoring Genotyping* Alaska State Public Health Laboratory Alaska State Public Health Laboratory Testing is only available at private reference labs in Alaska California Department of Health Services Mycobacteriology and Mycology Section 850 Marina Bay Parkway Richmond, CA 94804 Tel: (510) 412-3781 Within 24 hours from receipt of specimen in the laboratory Monday thru Friday only (closed on national holidays) Cultures are incubated for 6 weeks before reported as negative. Time to detection of Mycobacterial growth is dependent upon growth rate and quality of specimen. Identification of cultured mycobacteria is usually within 14-21 days from date of receipt (this can be dependent on factors such as overgrowth by other organisms). 28-35 days from date of receipt Within 24 – 72 hours from receipt of specimen in the laboratory Testing performed Monday, Wednesday and Friday Varies with laboratory Within 14 days of receipt of Mycobacterium tuberculosis complex isolates * All isolates of M. tuberculosis identified at the ASPHL are sent to the California Department of Health Services Laboratory for genotyping. On the rare occasion that M. tuberculosis is identified at another laboratory, arrangements must be made for isolates to be sent to the ASPHL so that genotyping can be done. A L A S K A T U B E R C U L O S I S P R O G R A M M A N U A L Laborator y Services 12.4 Revised November 2012
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Available Laboratory Tests<br />
Table 2: LABORATORY TESTS AVAILABLE IN ALASKA<br />
Test Laboratory Turnaround Time<br />
Diagnosis<br />
Acid-fast bacilli (AFB)<br />
smear (fluorochrome)<br />
<strong>Alaska</strong> <strong>State</strong> Public Health<br />
Laboratory<br />
Culture <strong>Alaska</strong> <strong>State</strong> Public Health<br />
Laboratory<br />
Drug susceptibility<br />
(first-line drugs only)<br />
Nucleic acid amplification<br />
(NAA) test<br />
Please see NAAT<br />
section 12.5<br />
QuantiFERON ® -TB Gold<br />
In-Tube (QFT-GIT)<br />
Epidemiologic Monitoring<br />
Genotyping*<br />
<strong>Alaska</strong> <strong>State</strong> Public Health<br />
Laboratory<br />
<strong>Alaska</strong> <strong>State</strong> Public Health<br />
Laboratory<br />
Testing is only available at<br />
private reference labs in<br />
<strong>Alaska</strong><br />
California Department <strong>of</strong> Health Services<br />
Mycobacteriology and Mycology Section<br />
850 Marina Bay Parkway<br />
Richmond, CA 94804<br />
Tel: (510) 412-3781<br />
Within 24 hours from receipt <strong>of</strong> specimen in<br />
the laboratory<br />
Monday thru Friday only (closed on national<br />
holidays)<br />
Cultures are incubated for 6 weeks before<br />
reported as negative. Time to detection <strong>of</strong><br />
Mycobacterial growth is dependent upon<br />
growth rate and quality <strong>of</strong> specimen.<br />
Identification <strong>of</strong> cultured mycobacteria is<br />
usually within 14-21 days from date <strong>of</strong> receipt<br />
(this can be dependent on factors such as<br />
overgrowth by other organisms).<br />
28-35 days from date <strong>of</strong> receipt<br />
Within 24 – 72 hours from receipt <strong>of</strong> specimen<br />
in the laboratory<br />
Testing performed Monday, Wednesday and<br />
Friday<br />
Varies with laboratory<br />
Within 14 days <strong>of</strong> receipt <strong>of</strong><br />
Mycobacterium tuberculosis<br />
complex isolates<br />
* All isolates <strong>of</strong> M. tuberculosis identified at the ASPHL are sent to the California Department <strong>of</strong> Health<br />
Services Laboratory for genotyping. On the rare occasion that M. tuberculosis is identified at another<br />
laboratory, arrangements must be made for isolates to be sent to the ASPHL so that genotyping can be<br />
done.<br />
A L A S K A T U B E R C U L O S I S P R O G R A M M A N U A L Laborator y Services 12.4<br />
Revised November 2012