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Surgery and Healing in the Developing World - Dartmouth-Hitchcock

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308 <strong>Surgery</strong> <strong>and</strong> <strong>Heal<strong>in</strong>g</strong> <strong>in</strong> <strong>the</strong> Develop<strong>in</strong>g <strong>World</strong><br />

Table 9. Subtotal thyroidectomy was carried out <strong>in</strong> 38 patients for <strong>in</strong>dications<br />

<strong>and</strong> results illustrated<br />

Indications for operation:<br />

Impend<strong>in</strong>g airway obstruction 10<br />

Massive Lipiodol-resistant gl<strong>and</strong>s 21<br />

Chronic dra<strong>in</strong><strong>in</strong>g s<strong>in</strong>uses 2<br />

Patient dissatisfaction with appearance 5<br />

Thyroid gl<strong>and</strong> removal median 0.5-1 kg (largest 1.8 kg)<br />

Thyroid gl<strong>and</strong> remnant 20-30 grams<br />

Deaths:<br />

Surgical 3<br />

1 postoperative airway obstruction (cret<strong>in</strong>)<br />

1 postoperative pulmonary embolus<br />

1 collapse second postoperative day, cause uncerta<strong>in</strong><br />

Medical 2<br />

1 suffocation<br />

1 thyroid storm<br />

Patients undergo<strong>in</strong>g thyroidectomy. Thirty-eight adults, represent<strong>in</strong>g 50% compliance of<br />

<strong>the</strong> 76 recommended for medical pre-operative preparation with at least four days Lugol’s<br />

solution (10 drops <strong>in</strong> water three times a day). Local anes<strong>the</strong>sia <strong>and</strong> cervical block (all),<br />

with Ethrane supplementation (four).<br />

tion was immediately stopped for all women of reproduc<strong>in</strong>g age <strong>and</strong> was broadened<br />

for <strong>in</strong>clusion of most children approach<strong>in</strong>g school age. 39<br />

Forty village leaders conducted a survey at ten years from <strong>the</strong> first <strong>in</strong>tervention<br />

(June 1993) <strong>and</strong> unanimously reported remarkably positive changes <strong>in</strong> each of <strong>the</strong><br />

<strong>in</strong>dividuals that had had iod<strong>in</strong>e repletion. With respect to each <strong>in</strong>dividual treated,<br />

<strong>the</strong>re was qualitative improvement (with <strong>the</strong> already noted exceptions of <strong>the</strong> complications<br />

of hyperthyroidism that were made possible by iod<strong>in</strong>e repletion—a condition<br />

known as Jod-Basedow’s syndrome—<strong>and</strong> complications due to regrowth of<br />

<strong>in</strong>trathoracic goiter or o<strong>the</strong>r postoperative events). Statements made by those adm<strong>in</strong>ister<strong>in</strong>g<br />

<strong>the</strong> program with<strong>in</strong> Sasal<strong>and</strong> were very enthusiastic. Kongonyesi, <strong>the</strong><br />

untir<strong>in</strong>g logistical assistant for <strong>the</strong> extended project, said, “Thank you for <strong>the</strong> goiter<br />

project. It heals people very much, <strong>the</strong>ir m<strong>in</strong>ds <strong>and</strong> bodies as well.” Of <strong>the</strong> o<strong>the</strong>r<br />

health <strong>in</strong>itiatives attempted with<strong>in</strong> this decade <strong>and</strong> this region, it is <strong>the</strong> most successful<br />

program <strong>in</strong> terms of compliance, susta<strong>in</strong>ability <strong>and</strong> behavioral changes.<br />

The immediate effect of medical <strong>in</strong>tervention <strong>in</strong> relief of hypothyroidism is dramatic<br />

<strong>in</strong> <strong>in</strong>dividual terms. With <strong>the</strong> rare exception of some medical complications<br />

of overactivity (as <strong>in</strong> <strong>the</strong> rare events of Jod-Basedow’s syndrome) <strong>the</strong> effects of iod<strong>in</strong>e<br />

repletion <strong>in</strong> nearly all <strong>in</strong>dividuals seem positive. Convert<strong>in</strong>g from <strong>the</strong> low-energy<br />

hypothyroid state to normal metabolic rate is a revolution <strong>in</strong> development potential<br />

measured <strong>in</strong> <strong>the</strong> <strong>in</strong>dividual patient. The <strong>in</strong>dividual successes with<strong>in</strong> <strong>the</strong> program<br />

can be viewed <strong>in</strong> summation <strong>in</strong> smaller groups of that population before look<strong>in</strong>g at<br />

<strong>the</strong> overall impact.<br />

Neuromotor response change was measured by several functions. Table 10 demonstrates<br />

<strong>the</strong> results of test<strong>in</strong>g <strong>the</strong> grip strength with <strong>the</strong> right h<strong>and</strong> (<strong>the</strong> Az<strong>and</strong>e of<br />

<strong>the</strong> Congo are permitted to only be right-h<strong>and</strong>ed) dynamometer for a population<br />

sample (n=50). Three years follow<strong>in</strong>g iod<strong>in</strong>e repletion, <strong>the</strong> mean was 24.88 kg

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