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Surgery and Healing in the Developing World - Dartmouth-Hitchcock

Surgery and Healing in the Developing World - Dartmouth-Hitchcock

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19<br />

182 <strong>Surgery</strong> <strong>and</strong> <strong>Heal<strong>in</strong>g</strong> <strong>in</strong> <strong>the</strong> Develop<strong>in</strong>g <strong>World</strong><br />

on one end <strong>and</strong> a po<strong>in</strong>t on <strong>the</strong> o<strong>the</strong>r. Because <strong>the</strong>y are somewhat flexible, <strong>the</strong>y<br />

provide alignment but not necessarily rigid fixation. They can be <strong>in</strong>serted percutaneously<br />

for treatment of most long bone fractures but are most useful for fractures<br />

of <strong>the</strong> lateral malleolus, radius, ulna <strong>and</strong> humerus.<br />

Infection<br />

Musculoskeletal <strong>in</strong>fections are endemic throughout <strong>the</strong> develop<strong>in</strong>g world. Polio,<br />

leprosy, tuberculosis <strong>and</strong> pyogenic osteomyelitis are major causes of disability <strong>in</strong> all<br />

such cultures. Polio <strong>and</strong> leprosy primarily <strong>in</strong>volve <strong>the</strong> neurologic system, <strong>and</strong> surgery<br />

is directed at <strong>the</strong> secondary musculoskeletal deformities. Tuberculosis <strong>and</strong> pyogenic<br />

<strong>in</strong>fections directly <strong>in</strong>vade bones, jo<strong>in</strong>ts <strong>and</strong> <strong>the</strong> sp<strong>in</strong>al column <strong>and</strong> thus damage<br />

both mobility <strong>and</strong> structural <strong>in</strong>tegrity of <strong>the</strong> skeletal system.<br />

Polio has been greatly reduced worldwide <strong>and</strong> current efforts are aimed at complete<br />

vacc<strong>in</strong>e prevention of new polio cases <strong>in</strong> <strong>the</strong> near future. When <strong>the</strong> acute<br />

disease is completely erradicated, <strong>the</strong>re will be residual deformities to be dealt with<br />

for many years to come. Corrective surgery is usually done electively <strong>and</strong> <strong>in</strong> concert<br />

with a rehabilitation program which <strong>in</strong>cludes brac<strong>in</strong>g, walk<strong>in</strong>g aids, <strong>and</strong> o<strong>the</strong>r mobility<br />

aids such as special wheelchairs. Simple percutaneous tendon releases or<br />

muscle-tendon leng<strong>the</strong>n<strong>in</strong>g followed by locally adapted spl<strong>in</strong>ts will yield significant<br />

functional improvement for most patients. More complex surgery <strong>in</strong>volv<strong>in</strong>g arthrodesis<br />

<strong>and</strong> tendon transfers should be attempted only if <strong>the</strong> local resources permit.<br />

Musculoskeletal deformities <strong>in</strong> <strong>the</strong> leprosy patient are secondary to <strong>the</strong> loss of<br />

motor function <strong>and</strong> sensation pr<strong>in</strong>cipally <strong>in</strong> <strong>the</strong> term<strong>in</strong>al portions of <strong>the</strong> extremities.<br />

It is estimated that <strong>the</strong>re are about 1.6 million people worldwide afflicted by<br />

leprosy although <strong>the</strong> disease is now treatable by comb<strong>in</strong>ation antibiotic <strong>the</strong>rapy.<br />

Like polio, <strong>the</strong> musculosketetal deformities are treated electively <strong>and</strong> <strong>in</strong>volve arthrodesis<br />

<strong>and</strong> tendon transfers. Most leprosy surgery is done <strong>in</strong> designated centers where<br />

resources <strong>and</strong> expertise can be concentrated <strong>and</strong> focused on this population.<br />

It has been estimated that <strong>the</strong> world prevalence of tuberculosis has reached 32%<br />

or about 1.8 billion people. In <strong>the</strong> develop<strong>in</strong>g countries, perhaps one-third of <strong>the</strong><br />

population with tuberculosis will have <strong>in</strong>volvement of <strong>the</strong> musculoskeletal system,<br />

pr<strong>in</strong>cipally <strong>the</strong> sp<strong>in</strong>e <strong>and</strong> lower extremities. Tuberculous <strong>in</strong>fection of major jo<strong>in</strong>ts is<br />

treated similar to management of pyogenic <strong>in</strong>fections with open dra<strong>in</strong>age of <strong>the</strong><br />

abscess, antimicrobial <strong>the</strong>rapy <strong>and</strong> restoration of function when <strong>the</strong> <strong>in</strong>fection is controlled.<br />

Often, because of <strong>the</strong> <strong>in</strong>dolent nature of this <strong>in</strong>fection, much jo<strong>in</strong>t destruction<br />

has already occurred by <strong>the</strong> time <strong>the</strong> diagnosis is made. In such cases arthrodesis<br />

follow<strong>in</strong>g <strong>the</strong> <strong>in</strong>itial debridement will provide satisfactory function <strong>in</strong> major weight<br />

bear<strong>in</strong>g jo<strong>in</strong>ts.<br />

Sp<strong>in</strong>al tuberculosis usually beg<strong>in</strong>s <strong>in</strong> <strong>the</strong> vertebral body caus<strong>in</strong>g significant bone<br />

destruction <strong>and</strong> kyphotic deformity. Notoriously, <strong>the</strong> cartilage of <strong>the</strong> disc spaces is<br />

preserved until late <strong>and</strong> with extension of <strong>the</strong> <strong>in</strong>fection, paraplegia occurs commonly<br />

from ei<strong>the</strong>r bony deformity or direct extension of <strong>the</strong> abscess <strong>in</strong>to <strong>the</strong> epidural space.<br />

Numerous protocols have evolved for deal<strong>in</strong>g with <strong>the</strong> tuberculous sp<strong>in</strong>e surgically<br />

<strong>and</strong> <strong>in</strong>clude abscess dra<strong>in</strong>age through ei<strong>the</strong>r a costotransversectomy approach or a<br />

transthoracic approach. In <strong>the</strong> latter, anterior bone graft<strong>in</strong>g us<strong>in</strong>g a rib or fibula is <strong>the</strong><br />

common procedure. The anterior aspect of <strong>the</strong> sp<strong>in</strong>al canal can be decompressed<br />

through ei<strong>the</strong>r of <strong>the</strong>se <strong>in</strong>cisions if sp<strong>in</strong>al cord <strong>in</strong>volvement has occurred. In areas<br />

where such surgery is not possible, medical treatment alone is used along with brac-

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