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DEPARTMENTS OF CHEMISTRY INDIANA PURDUE INDIANAPOLIS 1
INDIANA UNIVERSITY-
PURDUE UNIVERSITY
INDIANAPOLIS
logical interest; and (3) determination of the crystal
structures of novel structure-specific endonucleases.
TEL: (317) 278-8486 FAX: (317) 274-4686
Web: chem.iupui.edu/faculty/georgiadis
Email: mgeorgia@iupui.edu
Columbia University and The California Institute of
Technology. Bioorganic Chemistry; Chemical Biology.
The interaction of DNA and RNA with peptides, metal
complexes, and antibiotics; mechanisms of nucleic acid
strand scission; protein-nucleic acid interactions; pho-
402 N. Blackford St
Indianapolis, IN 46202-3274
TEL: (317) 274-6875
FAX: (317) 274-4701
Web: www.chem.iupui.edu
Email: jasiegel@iupui.edu
Department of Chemistry and Chemical Biology
Jay A. Siegel, Chair.
Degrees Offered: B.A, B.S, M.S, Ph.D.
Fields of Specialization: Analytical Chemistry, Biological
Chemistry, Inorganic Chemistry, Organic
Chemistry and Physical Chemistry.
Interdisciplinary Program: Ph.D./M.D. (Indiana
University School of Medicine); Ph.D., Molecular
Biophysics Program; Ph.D. and Biomedical Engineering.
BLACKLOCK, BRENDA J. (b.1965) Research Assistant
Professor. B.Sc, 1989, University of Waterloo;
Ph.D, 1994, University of Alberta. Postdoctoral Fellow,
1994-1997, Johns Hopkins University; Research Associate,
1997-2003, Miami University; Research Scholar,
2004-2005, Miami University. Biochemistry. Structure/
function studies of fatty acid elongases and desaturases
from plants, a cellular slime mold, and fungi. TEL: (317)
278-8181 FAX: (317) 274-4701
Web: www.chem.iupui.edu/faculty/blacklock
Email: bblacklo@iupui.edu
Robert E. Minto, Brenda J. Blacklock, Hina Younus and
Andrew C. Pratt, Atypical biosynthetic properties of a
Publication list has not been verified by the department.
Eric C. Long, Millie M. Georgiadis, Kristie D. Goodwin
and Mark A. Lewis, New approaches to analyzing the site selectivities
and crystal structures of DNA targeted metal complexes:
analysis of the antitumor agent bleomycin, ACS
Symp. Ser, 1012, 63-80 (2009).
LaTeca S. Glass, Binh Nguyen, Kristie D. Goodwin, Christophe
Dardonville, W. David Wilson, Eric C. Long and Millie
M. Georgiadis, Crystal Structure of a Trypanocidal 4,4’-
Bis(imidazolinylamino)diphenylamine Bound to DNA, Biochemistry,
48, 5943-5952 (2009).
Meihua Luo, Hongzhen He, Mark R. Kelley and Millie M.
Georgiadis, Redox regulation of DNA repair: implications
for human health and cancer therapeutic development, Antioxid.
Redox Signaling, 12, 1247-1269 (2010).
Kristie D. Goodwin, Hongzhen He, Tsuyoshi Imasaki,
Suk-Hee Lee and Millie M. Georgiadis, Crystal Structure of
the Human Hsmar1-Derived Transposase Domain in the
DNA Repair Enzyme Metnase, Biochemistry, 49, 5705-5713
(2010).
LaTeca S. Glass, Aditi Bapat, Mark R. Kelley, Millie M.
Georgiadis and Eric C. Long, Semi-automated high-throughput
fluorescent intercalator displacement-based discovery of
cytotoxic DNA binding agents from a large compound library,
Bioorg. Med. Chem. Lett, 20, 1685-1688 (2010).
GOODPASTER, JOHN V. (b.1973) Assistant Professor.
B.A, 1995, Gustavus Adolphus College; M.S,
2000, Michigan State University; Ph.D, 2000, Michigan
State University. NRC Postdoctoral Associate, 2001-
2002, NIST. Analytical Chemistry; Forensic Science.
My research interests lie in the ability of instrumental
and statistical methods to improve the detection of explosives
and the analysis of trace evidence. Specific projects
toactivation and oxygen activation of metal complexes.
TEL: (317) 274-6888 FAX: (317) 274-4701
Web: www.chem.iupui.edu/Faculty/Long
Email: eclong@iupui.edu
Eric C. Long, Ya-Yin Fang and Mark A. Lewis, DNA minor
groove recognition by Ni(II) and Cu(II) Gly-Gly-His
derived metallopeptides: models of protein and natural product
DNA recognition, ACS Symp. Ser, 1012, 219-241
(2009).
Eric C. Long, Millie M. Georgiadis, Kristie D. Goodwin
and Mark A. Lewis, New approaches to analyzing the site selectivities
and crystal structures of DNA targeted metal complexes:
analysis of the antitumor agent bleomycin, ACS
Symp. Ser, 1012, 63-80 (2009).
LaTeca S. Glass, Binh Nguyen, Kristie D. Goodwin, Christophe
Dardonville, W. David Wilson, Eric C. Long and Millie
M. Georgiadis, Crystal Structure of a Trypanocidal 4,4’-
Bis(imidazolinylamino)diphenylamine Bound to DNA, Biochemistry,
48, 5943-5952 (2009).
Brian M. Laing, Lisa Barrow-Laing, Maureen Harrington,
Eric C. Long and Donald E. Bergstrom, Properties of Double-Stranded
Oligonucleotides Modified with Lipophilic
Substituents, Bioconjugate Chem, 21, 1537-1544 (2010).
LaTeca S. Glass, Aditi Bapat, Mark R. Kelley, Millie M.
Georgiadis and Eric C. Long, Semi-automated high-throughput
fluorescent intercalator displacement-based discovery of
cytotoxic DNA binding agents from a large compound li-
brary, Bioorg. Med. Chem. Lett, 20, 1685-1688 (2010).
Aditi Bapat, LaTeca S. Glass, Meihua Luo, Melissa L.
Fishel, Eric C. Long, Millie M. Georgiadis and Mark R. Kelley,
Novel small-molecule inhibitor of apurinic/apyrimidinic
endonuclease 1 blocks proliferation and reduces viability of
glioblastoma cells, J. Pharmacol. Experimental Therapeutics,
334, 988-998 (2010).
Ya-Yin Fang, Vernon R. Morris, Guy M Lingani, Eric C.
12/
+ 3 desaturase from the model basidiomycete Phanerochaete
chrysosporium, Appl. Environ. Microbiol, 75, 1156-1164
(2009).
Brenda J. Blacklock, Brian E. Scheffler, Michael R. Shepard,
Naomi Jayasuriya and Robert E. Minto, Functional Diversity
in Fungal Fatty Acid Synthesis: The First Acetylenase
from the Pacific Golden Chanterelle, Cantharellus Formosus,
J. Biol. Chem, 285, 28442-28449 (2010).
BOYD, DONALD B. (b.1941) Research Professor.
B.S, 1963, The Pennsylvania State University; A.M,
1965, Harvard University; Ph.D, 1968, Harvard University.
NIH Fellowship, 1967-1968, Cornell University.
Computational Chemistry. Computer-aided drug design
(CADD), molecular modeling, cheminformatics, and
quantitative structure-activity relationships (QSAR).
involve designing novel laboratory methods for the identification
of chemical residues on post-blast debris, quan-
titative instrumental and statistical methods for the comparison
of class evidence, and fundamental studies of the
volatile and semi-volatile compounds emitted by explosive
formulations. TEL: (317) 274-6881 FAX: (317)
274-4701
Web: www.chem.iupui.edu/faculty/goodpaster
Email: jvgoodpa@iupui.edu
John V. Goodpaster and Elisa A. Liszewski, Forensic ana-
lysis of dyed textile fibers, Anal. Bioanal. Chem, 394, 2009-
2018 (2009).
Dee A. Turner and John V. Goodpaster, The effects of microbial
degradation on ignitable liquids, Anal. Bioanal.
Chem, 394, 363-371 (2009).
John V. Goodpaster, Amanda B. Sturdevant, Kristen L.
Long and WIlliam M. Southerland, Genome-targeted drug
design: Understanding the netropsin-DNA interaction, The
Open Conference Proceedings Journal, 1, 157-163 (2010).
J. B. Li, Design, synthesis and analysis of DNA minor
groove binding amino acid-phenylbenzimidazole conjugates.
(M)
L. S. Glass, Expedited approaches to the discovery and study
of novel DNA binding ligands. (M)
T. Wang, DNA recognition and cleavage by phenylbenzimidazole-modified
Gly-Gly-His derived metallopeptides.
(M)
MALIK, DAVID J. (b.1945) Chancellor’s Professor/
Executive Vice Chancellor, IU Northwest. B.S, 1968,
California State University, Hayward; M.S, 1969, California
State University, Hayward; Ph.D, 1976, Universi-
TEL: (317) 274-6891 FAX: (317) 274-4701
Web: chem.iupui.edu/Faculty/Boyd
Email: dboyd@iupui.edu
D. B. Boyd, Prospects for career opportunities in computational
chemistry, Reviews in Computational Chemistry, 27,
369-394 (2010).
GE, HAIBO (b.1972) Assistant Professor. M.S, 2001,
China Pharmaceutical University; Ph.D, 2006, The University
of Kansas. Research Associate, 2006-2009, The
Scripps Research Institute. Medicinal and/or Pharmaceutical
Chemistry; Organic Chemistry. Transition-metal-catalyzed
carbon-carbon and carbon-heteroatom bond
formation, and total synthesis and structure-activity relationship
studies of biologically active natural products.
TEL: (317) 274-6876 FAX: (317) 274-4701
Web: chem.iupui.edu
Email: geh@iupui.edu
Mingzong Li, Liangxi Li and Haibo Ge, Direct C3-alkeny-
lation of quinolones via palladium-catalyzed C-H functionalization
with low catalyst loading, Adv. Synth. Catal, 352,
2445-2449 (2010).
Ping Fang, Mingzong Li and Haibo Ge, Room Temperature
Palladium-Catalyzed Decarboxylative ortho-Acylation
of Acetanilides with -Oxocarboxylic Acids, J. Am. Chem.
Soc, 132, 11898-11899 (2010).
Mingzong Li and Haibo Ge, Decarboxylative Acylation of
Arenes with -Oxocarboxylic Acids via Palladium-Catalyzed
C-H Activation, Org. Lett, 12, 3464-3467 (2010).
GEORGIADIS, MILLIE M. Associate Professor.
B.S, 1984, Indiana University; Ph.D, 1990, University of
California, Los Angeles. Postdoctoral Research Fellow,
1990-1993, Columbia University. Structural Biology.
Current projects in the laboratory include the following:
(1) elucidation of the mechanism of redox regulation by
apurinic/apyrimidinic endonuclease; (2) development
and application of a high-throughput, high resolution
strategy to identify novel nucleic acid binding compounds
as potential inhibitors of specific targets of bio-
Andrews, Eileen M. Briley and Leanora Brun-Conti, Identification
and comparison of electrical tapes using instrumental
and statistical techniques: II. Organic composition of the tape
backing and adhesive, J. Forensic Sci, 54, 328-338 (2009).
Elisa A. Liszewski, Simon W. Lewis, Jay A. Siegel and
John V. Goodpaster, Characterization of automotive paint
clear coats by ultraviolet absorption microspectrophotometry
with subsequent chemometric analysis, Appl. Spectrosc, 64,
1122-1125 (2010).
Julie A. Barrett, Jay A. Siegel and John V. Goodpaster,
Forensic discrimination of dyed hair color: I. UV-visible microspectrophotometry,
J. Forensic Sci, 55, 323-333 (2010).
E. A. Liszewski, Instrumental and statistical methods for
the comparison of class evidence. (M)
E. H. Lotspeich, Evaluation of the odor compounds sensed
by explosive-detecting canines. (M)
LI, LEI (b.1973) Assistant Professor. B.S, 1996, Peking
University; M.Sc, 1999, Peking University; Ph.D, 2005,
Johns Hopkins University. Biochemistry; Bioinorganic
Chemistry. TEL: (317) 274-2202 FAX: (317) 274-4701
Web: www.chemistry.iupui.edu/Faculty/Li/
Email: lilei@iupui.edu
L. Li, D. P. Paterson, B. Lin, P. W. Coschigano and E. N.
G. Marsh, The subunit structure of benzylsuccinate synthase,
Biochemistry, 48, 1284–1292 (2009).
H. R. Lucas, L. Li, A. A. Sarjeant, M. A. Vance, A. E. Milligan,
E. I. Solomon and K. D. Karlin, Aliphatic C-H bond
oxidations initiated by a -1,2-peroxodicopper(II) complex,
J. Am. Chem. Soc, 131, 3230–3245 (2009).
G. Lin and L. Li, Revealing the spore photoproduct (SP)
formation via isotope labeling, Angewandte Chemie International
Edition, 9926-9929 (2010).
E. N. G. Marsh, D. Paterson and L. Li, Adenosyl radical:
Reagent and catalyst in enzyme reactions, Chem. Bio. Chem,
11, 604-621 (2010).
LONG, ERIC C. (b.1962) Professor. B.S, 1984, Albright
College; Ph.D, 1988, University of Virginia. Jane
Coffin Childs Memorial Fund Fellowship, 1989-1991,
ty of California, San Diego. Postdoctoral Research
Chemist, 1976-1977, University of California, San Die-
go; Research Associate, 1977-1980, University of Illi-
nois. Chemistry Education. Chemical education including
testing methods and pedagogical strategies for enhancing
learning and student success. TEL: (317) 274-
6884 FAX: (317) 274-4701
Web: www.chem.iupui.edu/faculty/malik
Email: dmalik@iupui.edu
Publication list has not been verified by the department.
D. J. Malik, C. Webb, R. G. Holdich, J. J. Ramsden, G. L.
Warwick, I. Roche, D. J. Williams, A. W. Trochimczuk, J. A.
Dale and N. A. Hoenich, Synthesis and characterization of
size-selective nanoporous polymeric adsorbents for blood pu-
rification, Sep. Purif. Technol, 66, 578-585 (2009).
Eszter Hazai, Istvan Hazai, Laszlo Demko, Sandor Kovacs,
David Malik, Peter Akli, Peter Hari, Julianna Szeman, Eva
Fenyvesi, Edina Benes, Lajos Szente and Zsolt Bikadi, Cyclodextrin
knowledgebase a web-based service managing
CD-ligand complexation data, J. Comput.-Aided Mol. Des,
24, 713-717 (2010).
MCCARTHY, JAMES R (b.1943) Research Profes-
sor. B.S, 1965, Arizona State University; Ph.D, 1969,
University of Utah. Medicinal and/or Pharmaceutical
Chemistry; Organic Chemistry. New methodology in the
area of organo-fluorine chemistry and application to the
synthesis of biologically active compounds. Design of
prodrugs and development of more efficient routes to existing
drugs. TEL: (317) 274-3642 FAX: (317) 274-4701
Web: chem.iupui.edu
Email: jarmccar@iupui.edu
D. M. Bender, J. A. Peterson, J. R. McCarthy, H. Gunaydin,
Y. Takano and K. N. Houk, Cyclopropanecarboxylic
acid esters as potential prodrugs with enhanced hydrolytic
stability, Org. Lett, 10, 509-511 (2008).
D. Zhang, D. Bender, F. Victor, J. A. Peterson, R. D. Boy-
er, G. A. Stephenson, A. Azman and J. R. McCarthy, Facile
rearrangement of N4-(alpha-Aminoacyl)cytidines to N-(4-

2 INDIANA PURDUE INDIANAPOLIS DEPARTMENTS OF CHEMISTRY
Cytidinyl)amino acid amides, Tetrahedron Lett, 49, 2052- Iwona Wrobel, Christopher C. M. Waterhouse, Xing Jun Li, Christoph Naumann, Suzanne M. Mithieux, David Szeke-
2055 (2008). Christophe C. Marchal, Natalie D. Stull, David B. Lewis, ly, Yidong Tu, Anthony S. Weiss and Philip W. Kuchel, Set-
D. M. Bender, J. Bao, A. H. Dantzig, W. D. Diseroad, K.
L. Law, N. A. Magnus, J. A. Peterson, E. J. Perkins, Y. J. Pu,
S. M. Reutzel-Edens, D. M. Remick, J. J. Starling, G. A.
MacGregor Steele, James D. Kellner, Weiming Yu, Samy O.
Meroueh, William M. Nauseef and Mary C. Dinauer, A new
genetic subgroup of chronic granulomatous disease with autosomal
recessive mutations in p40
ting paint” analogy for the hydrophobic self-association of
tropoelastin into elastin-like hydrogel, Biopolymers, 91, 321-
330 (2009).
phox Stephenson, R. K. Vaid, D. Zhang and J. R. McCarthy, Synthesis,
crystallization, and biological evaluation of an orally
active prodrug of gemcitabine, J. Med. Chem, 52, 6958-6961
(2009).
J. Green, D. M. Bender, S. Jackson, M. J. O’Donnell and J.
R. McCarthy, Nucleophiliic attack at a tertiary carbon with
inversion at ambient temperature, Org. Lett, 11, 807-810
(2009).
MCLEISH, MICHAEL J. (b.1954) Associate Professor.
B.Sc, 1979, La Trobe University (Australia); Ph.D,
1984, La Trobe University (Australia). Postdoctoral Fellow,
1983-1984, University of California, Berkeley; National
Research Fellow, 1985-1988, Victorian College of
Pharmacy (Australia). Biochemistry; Medicinal and/or
Pharmaceutical Chemistry. My primary research interests
lie in the broadly defined area of mechanistic enzymology.
Studies range from the development of rationally
designed enzyme inhibitors to the evolution of new
enzymes and pathways. TEL: (317) 274-6889 FAX:
(317) 274-4701
Web: chem.iupui.edu/Faculty/McLeish/
Email: mcleish@iupui.edu
Nyssa Drinkwater, Christine L. Gee, Munish Puri, Kevin
R. Criscione, Michael J. McLeish, Gary L. Grunewald and
Jennifer L. Martin, Molecular recognition of physiological
substrate noradrenaline by the adrenaline-synthesizing enzyme
PNMT and factors influencing its methyltransferase acand
selective defects
in neutrophil NADPH oxidase activity, Blood, 114, 3309-
3315 (2009).
Bin Xue, Liwei Li, Samy O. Meroueh, Vladimir N. Uversky
and A. Keith Dunker, Analysis of structured and intrinsically
disordered regions of transmembrane proteins, Mol.
BioSyst, 5, 1688-1702 (2009).
Liwei Li, Shide Liang, Meaghan M. Pilcher and Samy O.
Meroueh, Incorporating receptor flexibility in the molecular
design of protein interfaces, Protein Eng., Des. Sel, 22, 575-
586 (2009).
Shide Liang, Samy O. Meroueh, Guangce Wang, Chao Qiu
and Yaoqi Zhou, Consensus scoring for enriching near-native
structures from protein-protein docking decoys, Proteins:
Struct., Funct., Bioinf, 75, 397-403 (2009).
Liwei Li and Samy O. Meroueh, Receptor-ligand interactions
in biological systems, Wiley Encycl. Chem. Biol, 4,
208-221 (2009).
Liwei Li, Jing Li, May Khanna, Inha Jo, Jason P. Baird
and Samy O. Meroueh, Docking to Erlotinib Off-Targets
Leads to Inhibitors of Lung Cancer Cell Proliferation with
Suitable in Vitro Pharmacokinetics, ACS Med. Chem. Lett, 1,
229-233 (2010).
Yuying Wang, Joel M. Brittain, Brian W. Jarecki, Ki Duk
Park, Sarah M. Wilson, Bo Wang, Rachel Hale, Samy O.
Meroueh, Theodore R. Cummins and Rajesh Khanna, In Silico
Docking and Electrophysiological Characterization of Lacosamide
Binding Sites on Collapsin Response Mediator
Protein-2 Identifies a Pocket Important in Modulating Sodi-
Christoph Naumann and Philip W. Kuchel, NMR (Pro)chi-
ral Discrimination Using Polysaccharide Gels, Chem.—Eur.
J, 15, 12189-12191 (2009).
Uzi Eliav, Christoph Naumann, Gil Navon and Philip W.
Kuchel, Double quantum transition as the origin of the cen-
tral dip in the z-spectrum of HDO in variably stretched gel, J.
Magn. Reson, 198, 197-203 (2009).
S. Garg, J. X. Tang, J. Ruehe and C. A. Naumann, Actininduced
perturbation of PS lipid-cholesterol interaction: A
possible mechanism of cytoskeleton-based regulation of
membrane organization, J. Struct. Biol, 168, 11-20 (2009).
J. Herzler and C. Naumann, Shock-tube study of the igni-
tion of methane/ethane/hydrogen mixtures with hydrogen
contents from 0% to 100% at different pressures, Proc. Com-
bust. Inst, 32, 213-220 (2009).
J. Herbst, J. Herzler, T. Kick and C. Naumann, Study on
the combustion of natural gas reference fuel in oxyfuel con-
ditions, VDI-Ber, 2056, 211-216 (2009).
A. P. Siegel and C. A. Naumann, Polymer stabilized lipid
membranes: Langmuir monolayers, Adv. Polym. Sci, 224, 43-
85 (2010).
Wolfgang Knoll, Katja Bender, Renate Foerch, Curt Frank,
Heide Goetz, Claudia Heibel, Toby Jenkins, Ulrich Jonas,
Asmorom Kibrom, Ralf Kuegler, Christoph Naumann, Renate
Naumann, Annette Reisinger, Juergen Ruehe, Stefan
Schiller and Eva-Kathrin Sinner, Polymer-tethered biomole-
cular lipid membranes, Adv. Polym. Sci, 224, 87-111 (2010).
Christoph Naumann and Philip William Kuchel, NMR of
Na + tivity, Biochem. J, 422, 463-471 (2009).
Gabriel S. Brandt, Malea M. Kneen, Sumit Chakraborty,
Ahmet T. Baykal, Natalia Nemeria, Alejandra Yep, David I.
Ruby, Gregory A. Petsko, George L. Kenyon, Michael J.
McLeish, Frank Jordan and Dagmar Ringe, Snapshot of a
reaction intermediate: analysis of benzoylformate decarboxylase
in complex with a benzoylphosphonate inhibitor, Biochemistry,
48, 3247-3257 (2009).
Alejandra Yep and Michael J. McLeish, Engineering the
substrate binding site of benzoylformate decarboxylase, Biochemistry,
48, 8387-8395 (2009).
Sumit Chakraborty, Natalia S. Nemeria, Anand Balakrishnan,
Gabriel S. Brandt, Malea M. Kneen, Alejandra Yep, Michael
J. McLeish, George L. Kenyon, Gregory A. Petsko,
Dagmar Ringe and Frank Jordan, Detection and time course
of formation of major thiamin diphosphate-bound covalent
intermediates derived from a chromophoric substrate analogue
on benzoylformate decarboxylase, Biochemistry, 48,
981-994 (2009).
Polina Georgieva, Qian Wu, Michael J. McLeish and Fahmi
Himo, The reaction mechanism of phenylethanolamine N-
methyltransferase: A density functional theory study, Biochim.
Biophys. Acta, Proteins Proteomics, 1794, 1831-1837
um Channel Slow Inactivation, J. Biol. Chem, 285, 25296-
25307 (2010).
Liwei Li, Khuchtumur Bum-Erdene, Peter H. Baenziger,
Joshua J. Rosen, Jamison R. Hemmert, Joy A. Nellis, Marlon
E. Pierce and Samy O. Meroueh, BioDrugScreen: a computational
drug design resource for ranking molecules docked to
the human proteome, Nucleic Acids Res, 38, D765-D773
(2010).
MINTO, ROBERT E. (b.1966) Associate Professor.
B.Sc, 1989, University of Waterloo; Ph.D, 1994, Univer-
sity of California, Berkeley. Postdoctoral Fellow, 1994-
1997, The Johns Hopkins University. Biochemistry; Organic
Chemistry. Bioorganic chemistry. Biochemistry
and molecular biology of fungal and plant lipid secondary
metabolism. Structural and mechanistic studies of
desaturases and related transmembrane proteins. Synthet-
ic and physical organic chemistry of acetylenes. TEL:
(317) 274-6869 FAX: (317) 274-4701
Web: chem.iupui.edu/Faculty/Minto/
Email: rminto@iupui.edu
Robert E. Minto, Brenda J. Blacklock, Hina Younus and
Andrew C. Pratt, Atypical biosynthetic properties of a
, glycine and HDO in isotropic and anisotropic carra-
geenan gels, Polym. Chem, 1, 1109-1116 (2010).
NUROK, DAVID (b.1938) Associate Professor Emeritus.
B.S, 1959, University of Cape Town; Ph.D, 1966,
University of Cape Town. Postdoctoral Fellowship,
1977, University of Houston. Analytical Chemistry. Planar
electrochromatography and pressurized planar electrochromatography.
TEL: (317) 274-6886 FAX: (317)
274-4701
Web: www.chem.iupui.edu/faculty/nurok
Email: dnurok@iupui.edu
Scott D. Woodward, Iva Urbanova, David Nurok and Fran-
tisek Svec, Separation of Peptides and Oligonucleotides Using
a Monolithic Polymer Layer and Pressurized Planar Elec-
trophoresis and Electrochromatography, Anal. Chem. (Wash-
ington, DC, U. S.), 82, 3445-3448 (2010).
O’DONNELL, MARTIN J. (b.1946) Chancellor’s
Professor. B.S, 1968, University of Iowa; Ph.D, 1973,
Yale University. Postdoctoral Fellowship, 1973-1975,
Université Catholique de Louvain, Belgium. Organic
12/
(2009).
Qian Wu, Joanne M. Caine, Stuart A. Thomson, Meri Sla-
vica, Gary L. Grunewald and Michael J. McLeish, Time-dependent
inactivation of human phenylethanolamine N-methyltransferase
by 7-isothiocyanatotetrahydroisoquinoline, Bioorg.
Med. Chem. Lett, 19, 1071-1074 (2009).
Pan-Fen Wang, Alejandra Yep, George L. Kenyon and Michael
J. McLeish, Using directed evolution to probe the substrate
specificity of mandelamide hydrolase, Protein Eng.
Des. Sel, 22, 103-110 (2009).
Nyssa Drinkwater, Hoan Vu, Kimberly M. Lovell, Kevin
R. Criscione, Brett M. Collins, Thomas E. Prisinzano, Sally-
Ann Poulsen, Michael J. McLeish, Gary L. Grunewald and
Jennifer L. Martin, Fragment-based screening by X-ray crystallography,
MS and isothermal titration calorimetry to identify
PNMT (phenylethanolamine N-methyltransferase) inhi-
+ 3 desaturase from the model basidiomycete Phanerochaete
chrysosporium, Appl. Environ. Microbiol, 75, 1156-1164
(2009).
Brenda J. Blacklock, Brian E. Scheffler, Michael R. She-
pard, Naomi Jayasuriya and Robert E. Minto, Functional Di-
versity in Fungal Fatty Acid Synthesis: The First Acetylenase
from the Pacific Golden Chanterelle, Cantharellus Formosus,
J. Biol. Chem, 285, 28442-28449 (2010).
MUHOBERAC, BARRY B. (b.1950) Associate Professor.
B.S, 1972, Louisiana State University-New Orleans;
Ph.D, 1978, University of Virginia. Postdoctoral
Fellowship, 1978, University of Texas, Health Science
Center, San Antonio, Department of Biochemistry. Biochemistry;
Biophysics/Biophysical Chemistry. Spectro-
Chemistry; Synthesis. Synthetic methods in amino acid
and peptide chemistry, phase-transfer reactions, asym-
metric synthesis, organometallic chemistry, solid-phase
organic synthesis and combinatorial chemistry. TEL:
(317) 274-6887 FAX: (317) 274-4701
Web: www.chem.iupui.edu/faculty/odonnell
Email: modonnel@iupui.edu
William L. Scott, Jordi Alsina, Christopher O. Audu,
Evgenii Babaev, Linda Cook, Jeffery L. Dage, Lawrence A.
Goodwin, Jacek G. Martynow, Dariusz Matosiuk, Miriam
Royo, Judith G. Smith, Andrew T. Strong, Kirk Wickizer,
Eric M. Woerly, Ziniu Zhou and Martin J. O’Donnell, Distributed
Drug Discovery, Part 2: Global Rehearsal of Alkylat-
ing Agents for the Synthesis of Resin-Bound Unnatural Ami-
no Acids and Virtual D3 bitors, Biochem. J, 431, 51-61 (2010).
Rex F. Pratt and Michael J. McLeish, Structural relation-
ship between the active sites of ß-lactam-recognizing and
amidase signature enzymes: convergent evolution?, Bio-
chemistry, 49, 9688-9697 (2010).
Gabriel S. Brandt, Malea M. Kneen, Gregory A. Petsko,
Dagmar Ringe and Michael J. McLeish, Active-site engineering
of benzaldehyde lyase shows that a point mutation can
confer both new reactivity and susceptibility to mechanismbased
inhibition, J. Am. Chem. Soc, 132, 438-439 (2010).
scopic and biochemical studies of structure-function relationships
in biological systems, including interactions of
metal ions and substrates with proteins and biomembranes,
and larger scale macromolecular associations that
are found in neurodegenerative diseases. TEL: (317)
274-6885 FAX: (317) 274-4701
Web: www.chem.iupui.edu/faculty/muhoberac
Email: bmuhober@iupui.edu
Martin A. Baraibar, Barry B. Muhoberac, Holly J. Garring-
Catalog Construction, J. Comb.
Chem, 11, 14-33 (2009).
William L. Scott and Martin J. O’Donnell, Distributed
Drug Discovery, Part 1: Linking Academia and Combinatorial
Chemistry to Find Drug Leads for Developing World Di-
seases, J. Comb. Chem, 11, 3-13 (2009).
William L. Scott, Christopher O. Audu, Jeffery L. Dage,
Lawrence A. Goodwin, Jacek G. Martynow, Laura K. Platt,
Judith G. Smith, Andrew T. Strong, Kirk Wickizer, Eric M.
Woerly and Martin J. O’Donnell, Distributed Drug Discovery,
Part 3: Using D3 MEROUEH, SAMY O. (b.1973) Assistant Professor.
B.Sc, 1995, Wayne State University; Ph.D, 2001, Wayne
State University. Postdoctoral Research Associate, 2001-
2003, Wayne State University; Postdoctoral Research
Associate, 2003-2004, Notre Dame; Postdoctoral Fellow,
2004-2007, University of Notre Dame. Chemical Biology;
Computational Chemistry. TEL: (317) 274-8315
FAX: (317) 274-9217
Web: www.chem.iupui.edu/faculty/Meroueh/
Email: smeroueh@iupui.edu
er, Thomas D. Hurley and Ruben Vidal, Unraveling of the E-
helices and Disruption of 4-Fold Pores Are Associated with
Iron Mishandling in a Mutant Ferritin Causing Neurodegeneration,
J. Biol. Chem, 285, 1950-1956 (2010).
NAUMANN, CHRISTOPH A. (b.1964) Associate
Professor. Ph.D, 1995, Technical University Munich.
Research Associate, 1995-1996, Technical University
Munich; Research Associate, 1996, Max-Planck-Institute
for Polymer Research Mainz; Research Associate, 1996-
1999, Stanford University. Biophysics/Biophysical
Methodology to Synthesize Analogs of
an Anti-Melanoma Compound, J. Comb. Chem, 11, 34-43
(2009).
William L. Scott, Ziniu Zhou, Jacek G. Martynow and
Martin J. O’Donnell, Solid-Phase Synthesis of Amino- and
Carboxyl-Functionalized Unnatural -Amino Acid Amides,
Org. Lett, 11, 3558-3561 (2009).
Jonathan E. Green, David M. Bender, Stona Jackson, Mar-
tin J. O’Donnell and James R. McCarthy, Mitsunobu approach
to the synthesis of optically active ,-disubstituted
amino acids, Org. Lett, 11, 807-810 (2009).
William L. Scott, Ziniu Zhou, Pawel Zajdel, Maciej Paw-
Shide Liang, Liwei Li, Wei-Lun Hsu, Meaghan N. Pilcher,
Vladimir Uversky, Yaoqi Zhou, A. Keith Dunker and Samy
O. Meroueh, Exploring the Molecular Design of Protein Interaction
Sites with Molecular Dynamics Simulations and
Free Energy Calculations, Biochemistry, 48, 399-414 (2009).
Chemistry; Nanochemistry. TEL: (317) 278-2512 FAX:
(317) 274-4701
Web: www.chem.iupui.edu/faculty/naumann
Email: naumann@chem.iupui.edu
lowski and Martin J. O’Donnell, Solid-phase synthetic route
to multiple derivatives of a fundamental peptide unit, Molecules,
15, 4961-4983 (2010).
Lindsey G. Fischer, Solid-phase synthesis of N-carboxy-
Juan D. Matute, Andres A. Arias, Nicola A. M. Wright, Publication list has not been verified by the department. alkyl unnatural amino acids. (M)

DEPARTMENTS OF CHEMISTRY INDIANA PURDUE INDIANAPOLIS 3
OH, KYUNGSOO (b.1971) Associate Professor. B.Sc, Royce W. Murray, Gold nanoparticles: Past, present, and fu- John V. Goodpaster, Characterization of automotive paint
1999, University of London; D.Phil, 2003, University of ture, Langmuir, 25, 13840-13851 (2009).
clear coats by ultraviolet absorption microspectrophotometry
Sussex. Research Associate, 2002-2005, University of
Pennsylvania. Bioorganic Chemistry; Organic Chemistry.
Development of synthetic methodologies applied to
biologically important molecules, cycloaddition and
fragmentation reactions in natural product synthesis, biological
studies of natural and non-natural products, biological
activity of modified nucleotides, structure-activity
relationships of potential antiviral drug candidates.
TEL: (317) 278-7531 FAX: (317) 274-4701
Web: www.chem.iupui.edu/Faculty/Oh/
Email: ohk@iupui.edu
Hun Young Kim, Hui-Ju Shih, William E. Knabe and
Kyungsoo Oh, Reversal of Enantioselectivity between the
Copper(I)- and Silver(I)-Catalyzed 1,3-Dipolar Cycloaddition
Reactions Using a Brucine-Derived Amino Alcohol Li-
gand, Angew. Chem., Int. Ed, 48, 7420-7423 (2009).
Hun Young Kim and Kyungsoo Oh, Brucine-derived amino
alcohol-catalyzed asymmetric Henry reaction: An orthogonal
enantioselectivity approach, Organic Letters, 8, 5682-
5685 (2009).
Kyungsoo Oh and William Eric Knabe, Lewis acid-promoted
electron transfer deoxygenation of epoxides, sulfoxides,
and amine N-oxides: the role of low-valent niobium
complexes from NbCl5 and Zn, Tetrahedron, 65, 2966-2974
(2009).
Hun Young Kim, Sungkyung Kim and Kyungsoo Oh, Orthogonal
Enantioselectivity Approaches Using Homogeneous
and Heterogeneous Catalyst Systems: Friedel-Crafts Alkyla-
tion of Indole, Angew. Chem., Int. Ed, 49, 4476-4478 (2010).
Kyungsoo Oh, Jian-Yuan Li and Jinhyang Ryu, Brucine N-
Rajesh Sardar, Christopher A. Beasley and Royce W. Murray,
Interfacial Ion Transfers between a Monolayer Phase of
Cationic Au Nanoparticles and Contacting Organic Solvent,
J. Am. Chem. Soc, 132, 2058-2063 (2010).
Christopher A. Beasley, Rajesh Sardar, Neil M. Barnes and
Royce W. Murray, Persistent Multilayer Electrode Adsorp-
tion of Polycationic Au Nanoparticles, J. Phys. Chem. C,
114, 18384-18389 (2010).
R. Sardar, P. M. Shem, C. Pecchia-Bekkum, N. S. Bjorge
and J. S. Shumaker-Parry, Single-step generation of fluorophore-encapsulated
gold nanoparticle core-shell materials,
Nanotechnology, 21, 345603 (2010).
SCHULTZ, FRANKLIN A. (b.1941) Professor Emeritus.
B.S, 1963, California Institute of Technology;
Ph.D, 1967, University of California, Riverside. Electrochemistry;
Inorganic Chemistry. Relationships between
structure and electron-transfer reactivity of transition metal
compounds; active site models for molybdenum-containing
enzymes; coupled electron-transfer and spincrossover
reactions; multielectron transfer reactions.
TEL: (541) 536-3880 FAX: (317) 274-4701
Web: www.chem.iupui.edu/faculty/schultz
Email: fschultz@iupui.edu
schultz@chem.iupui.edu
Franklin A. Schultz, Richard L. Lord, Xiaofan Yang and
Mu-Hyun Baik, Inorganic models for two-electron redox
chemistry in biological systems: ligand-bridged molybdenum
and tungsten dimers, ACS Symp. Ser, 1012, 151-166 (2009).
Richard L. Lord, Franklin A. Schultz and Mu-Hyun Baik,
Spin Crossover-Coupled Electron Transfer of [M(tacn)2]
with subsequent chemometric analysis, Appl. Spectrosc, 64,
1122-1125 (2010).
Julie A. Barrett, Jay A. Siegel and John V. Goodpaster,
Forensic discrimination of dyed hair color: I. UV-visible microspectrophotometry,
J. Forensic Sci, 55, 323-333 (2010).
VARMA-NELSON, PRATIBHA Professor. B.S,
1970, Poona University, India; Ph.D, 1978, University of
Illinois-Chicago. Postdoctoral Fellow, 1977-1979,
Stritch School of Medicine, Loyola University. Chemistry
Education; Organic Chemistry. TEL: (317) 278-3425
FAX: (317) 274-4701
Web: chem.iupui.edu
Email: pvn@iupui.edu
Publication list has not been verified by the department.
David K. Gosser, Jr., Jack A. Kampmeier and Pratibha
Varma-Nelson, Peer-led team learning: 2008 James Flack
Norris Award address, J. Chem. Educ, 87, 374-380 (2010).
3+/2+
oxide-catalyzed Morita-Baylis-Hillman reaction of vinyl ketones:
a mechanistic implication of dual catalyst system with
proline, Org. Biomol. Chem, 8, 3015-3024 (2010).
Complexes (tacn = 1,4,7-Triazacyclononane; M = Cr, Mn,
Fe, Co, Ni), J. Am. Chem. Soc, 131, 6189-6197 (2009).
Richard L. Lord, Franklin A. Schultz and Mu-Hyun Baik,
PU, JINGZHI Assistant Professor. B.S, 1999, Peking
University; Ph.D, 2004, University of Minnesota. Postdoctoral,
2004-2005, University of Minnesota; Postdoc-
Two-Electron Redox Energetics in Ligand-Bridged Dinuclear
Molybdenum and Tungsten Complexes, Inorg. Chem.
(Washington, DC, U. S.), 49, 4611-4619 (2010).
toral, 2005-2010, Harvard University. Theoretical Chem- SCOTT, WILLIAM L. (b.1945) Research Professor.
istry. TEL: (317) 278-5721 FAX: (317) 274-4701 B.A, 1967, Williams College; Ph.D, 1972, University of
Email: jpu@iupui.edu California, Los Angeles. NIH Postdoctoral Fellow, 1972-
J. Pu and M. Karplus, How subunits coupling produces the
rotary motion in F1-ATPase, PNAS, 105, 1192-1197 (2008).
B. R. Brooks, C. L. Brooks, III, A. D. Mackerell, Jr., L.
Nilsson, R. J. Petrella, B. Roux, Y. Won, G. Archontis, C.
Bartels, S. Boresch, A. Caflisch, L. Caves, Q. Cui, A. R. Din-
1973, Rockefeller University; NIH Postdoctoral Fellow,
1973-1974, California Institute of Technology. Medici-
nal and/or Pharmaceutical Chemistry; Organic Chemistry.
My main focus is the development and implementation
of IUPUI’s Distributed Drug Discovery (D3) proner,
M. Feig, S. Fischer, J. Gao, M. Hodoscek, W. Im, K.
Kuczera, T. Lazaridis, J. Ma, V. Ovchinnikov, E. Paci, R. W.
Pastor, C. B. Post, J. Z. Pu, M. Schaefer, B. Tidor, R. M.
Venable, H. L. Woodcock, X. Wu, W. Yang, D. M. York and
M. Karplus, CHARMM: The biomolecular simulation program,
J. Comput. Chem, 30, 1545-1614 (2009).
gram to discover drug leads for neglected diseases. This
involves creation of simple, inexpensive equipment and
new solid-phase synthetic methodology to educate students
while they make, as potential drug leads, a wide
range of peptidomimetic and biomimetic molecules and
scaffolds. Many of these molecules are conformationally
SARDAR, RAJESH (b.1978) Assistant Professor.
B.Sc, 1999, University of Calcutta; M.Sc, 2001, Indian
Institute of Technology, Kharagpur; Ph.D, 2006, The
Graduate Center, City University of New York. Faculty
Intern, 2006-2008, University of Utah; Postdoctoral Fellow,
2008-2010, University of North Carolina, Chapel
Hill. Analytical Chemistry; Nanochemistry. TEL: (317)
constrained. Some are substituted and unsubstituted unnatural
amino acids. TEL: (317) 274-6880 FAX: (317)
274-4701
Web: www.chem.iupui.edu/faculty/scott
Email: wscott@iupui.edu
William L. Scott, Jordi Alsina, Christopher O. Audu,
Evgenii Babaev, Linda Cook, Jeffery L. Dage, Lawrence A.
Goodwin, Jacek G. Martynow, Dariusz Matosiuk, Miriam
278-2511 FAX: (317) 274-4701
Royo, Judith G. Smith, Andrew T. Strong, Kirk Wickizer,
Web: www.chem.iupui.edu/Faculty/Sardar/
Eric M. Woerly, Ziniu Zhou and Martin J. O’Donnell, Distri-
Email: rsardar@iupui.edu
Rajesh Sardar, Tyler B. Heap and Jennifer S. Shumaker-
buted Drug Discovery, Part 2: Global Rehearsal of Alkylating
Agents for the Synthesis of Resin-Bound Unnatural Amino
Acids and Virtual D3 Parry, Versatile solid phase synthesis of gold nanoparticle dimers
using an asymmetric functionalization approach, J. Am.
Chem. Soc, 129, 5356–5357 (2007).
Rajesh Sardar, Jong-Won Park and Jennifer S. Shumaker-
Parry, Polymer-induced synthesis of stable gold and silver
nanoparticles and subsequent ligand exchange in water,
Langmuir, 23, 11883–11889 (2007).
Rajesh Sardar, Natalie S. Bjorge and Jennifer S. Shumaker-Parry,
PH-controlled assemblies of polymeric amine-stabilized
gold nanoparticles, Macromolecules, 41, 4347-4352
Catalog Construction, J. Comb.
Chem, 11, 14-33 (2009).
William L. Scott and Martin J. O’Donnell, Distributed
Drug Discovery, Part 1: Linking Academia and Combinatorial
Chemistry to Find Drug Leads for Developing World Diseases,
J. Comb. Chem, 11, 3-13 (2009).
William L. Scott, Christopher O. Audu, Jeffery L. Dage,
Lawrence A. Goodwin, Jacek G. Martynow, Laura K. Platt,
Judith G. Smith, Andrew T. Strong, Kirk Wickizer, Eric M.
Woerly and Martin J. O’Donnell, Distributed Drug Discov-
ery, Part 3: Using D3 (2008).
Rajesh Sardar and Jennifer S. Shumaker-Parry, Asymmetrically
functionalized gold nanoparticles organized in onedimensional
chains, Nano Lett, 8, 731–736 (2008).
Rajesh Sardar, Christopher A. Beasley and Royce W. Murray,
Ferrocenated Au Nanoparticle Monolayer Adsorption on
Self-Assembled Monolayer-Coated Electrodes, Anal. Chem.
(Washington, DC, U. S.), 81, 6960-6965 (2009).
Rajesh Sardar and Jennifer S. Shumaker-Parry, 9-BBN Induced
Synthesis of Nearly Monodisperse -Functionalized
Alkylthiol Stabilized Gold Nanoparticles, Chem. Mater, 21,
Methodology to Synthesize Analogs of
an Anti-Melanoma Compound, J. Comb. Chem, 11, 34-43
(2009).
William L. Scott, Ziniu Zhou, Jacek G. Martynow and
Martin J. O’Donnell, Solid-Phase Synthesis of Amino- and
Carboxyl-Functionalized Unnatural -Amino Acid Amides,
Org. Lett, 11, 3558-3561 (2009).
William L. Scott, Ziniu Zhou, Pawel Zajdel, Maciej Pawlowski
and Martin J. O’Donnell, Solid-phase synthetic route
to multiple derivatives of a fundamental peptide unit, Molec-
ules, 15, 4961-4983 (2010).
1167-1169 (2009).
Christina A. Fields-Zinna, Rajesh Sardar, Christopher A.
Beasley and Royce W. Murray, Electrospray Ionization Mass
Spectrometry of Intrinsically Cationized Nanoparticles,
[Au144/146(SC11H22N(CH2CH3)3
SIEGEL, JAY A. (b.1946) Professor. B.S, 1968,
George Washington University; M.S, 1970, George
Washington University; Ph.D, 1976, George Washington
University. Forensic Science. Fire residues, fibers, glass,
+ )x(S(CH2)5CH3)y] x+ , J. Am.
Chem. Soc, 131, 16266-16271 (2009).
Patrick M. Shem, Rajesh Sardar and Jennifer S. Shumaker-
Parry, One-Step Synthesis of Phosphine-Stabilized Gold Nanoparticles
Using the Mild Reducing Agent 9-BBN, Lang-
muir, 25, 13279-13283 (2009).
soil, illicit drugs and paints. TEL: (317) 274-6883 FAX:
(317) 274-4701
Web: www.chem.iupui.edu/faculty/siegel
Email: jasiegel@iupui.edu
siegel.jay@gmail.com
Rajesh Sardar, Alison M. Funston, Paul Mulvaney and Elisa A. Liszewski, Simon W. Lewis, Jay A. Siegel and