Metabolomics - CERM
Metabolomics - CERM Metabolomics - CERM
PCA Plot Nomenclature • PCA Generate 2 kinds of plots, the scores plot and the loadings plot • Scores plot (on right) plots the data using the main principal components original data Z = X W scores loading
PCA Loadings Plot • Loadings plot shows how much each of the variables (metabolites) contributed to the different principal components • Variables at the extreme corners contribute most to the scores plot separation
- Page 1 and 2: Metabolomics Leonardo Tenori FiorGe
- Page 3 and 4: “La metabolomica è l’ultima na
- Page 5 and 6: Metabolomica: la nuova frontiera
- Page 7 and 8: Metabonomics “…measurement of t
- Page 9 and 10: Metabolomica: alcuni obiettivi Valu
- Page 11 and 12: Metabolomica: alcuni obiettivi Scop
- Page 13 and 14: The metabolome consists of what? Sm
- Page 15 and 16: C om p ound class N u m b er C om p
- Page 17 and 18: Why 1 µM? Equals ~200 ng/mL Limit
- Page 19 and 20: Medical Metabolomics Generate metab
- Page 21 and 22: Traditional Metabolite Analysis HPL
- Page 23 and 24: What’s the Difference Between Met
- Page 25 and 26: Advantages Measure multiple (10’s
- Page 27 and 28: 2 Routes to Metabolomics Two approa
- Page 29 and 30: Benefits of analyzing the metabolom
- Page 31 and 32: Advantages: Use of NMR in Non-destr
- Page 33 and 34: Raccolta e stoccaggio dei campioni
- Page 35 and 36: NMR A typical 950-MHz H NMR spectru
- Page 37 and 38: Profilo 1 H NMR di urina umana
- Page 39 and 40: Profilo di siero umano Proteins + L
- Page 41 and 42: Data analysis - approach Classify N
- Page 43: PCA Unsupervised Multivariate analy
- Page 53 and 54: SIMCA Supervised learning method ba
- Page 55 and 56: OPLS OPLS method is a recent modifi
- Page 57 and 58: Targeted profiling Targeted metabol
- Page 59 and 60: Databases
- Page 61 and 62: Effetto della dieta Trimetilammina
- Page 63 and 64: Effetto delle patologie Campioni di
- Page 65 and 66: METabolomic REFerence The METREF pr
- Page 67 and 68: Ind 1 Ind 2 METabolomic REFerence G
- Page 69 and 70: METabolomic REFerence Dendrogram of
- Page 71 and 72: METabolomic REFerence An individual
- Page 73 and 74: METabolomic REFerence 2 Experimenta
- Page 75 and 76: METabolomic REFerence 2 2005 collec
- Page 77 and 78: Un “salto” metabolico Evoluzion
- Page 79 and 80: Celiac Disease Metabolomics Experim
- Page 81 and 82: Celiac Disease Metabolomics Note: b
- Page 83 and 84: Celiac Disease Metabolomics Celiac
- Page 85 and 86: Celiac Disease Metabolomics Cluster
- Page 87 and 88: Potential celiac disease Subjects:
- Page 89 and 90: Celiachia Potenziale Celiaci - Sani
- Page 91 and 92: ACIDO LINOLENICO REGIONE DEI METILI
- Page 93 and 94: PRODOTTI DI OSSIDAZIONE QUASI ASSEN
PCA Plot Nomenclature<br />
• PCA Generate 2<br />
kinds of plots, the<br />
scores plot and the<br />
loadings plot<br />
• Scores plot (on<br />
right) plots the data<br />
using the main<br />
principal<br />
components<br />
original<br />
data<br />
Z = X W<br />
scores loading
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