ANTI-NUTRITIONAL CONSTITUENT OF COLOCASIA ESCULENTA ...

ANTI-NUTRITIONAL CONSTITUENT OF COLOCASIA ESCULENTA ... ANTI-NUTRITIONAL CONSTITUENT OF COLOCASIA ESCULENTA ...

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2.3 Cbaracterization and nntritional evaluation ofselected anti-nutrients in Amadumbe The characterization of two anti-nutients a-amylase inhibitors and gamma-sitosterol highlighted some of the benefits of the consumption of Amadumbe. The a-amylase inhibitors present in the Amadumbe tubers showed inlnbitory activity against mammalian amylases and could therefore cause a marked decrease in the availability of digested starch. This may be beneficial in the management ofdiabetes mellitus and obesity. Gamma-sitosterol was also isolated from Amadumbe tubers. It is an isomer of beta­ sitosterol which is a highly active biological compound. The nutritional evaluation of beta-sitosterol has shown that by lowering the activity ofdisaccharidases, it could cause a decrease in glucose concentration in the blood of rats. Therefore the gamma-sitosterol present in these tubers could possibly be valuable by reducing blood sugar levels in diabetics and obesity. The death rate among adults in South Africa is increasing. AIDS-related illnesses are not likely to be the entire reason for the increase in death rates. With reported increase in urbanization and the associated changes in life-style, incidences of obesity and diabetes could be additional factors. The results of this study do suggest that even though Amadumbe is a neglected crop in South Africa, it is a highly nutritional crop, the consumption ofwhich could be beneficial to diabetic and hypertensive patients. 235

2.4 Suggestions for future work Further studies on Amadumbe are suggested on these lines 1. To extract and partially characterize other anti-nutritional factors in Amadumbe tubers. 2. Studies on the properties ofthese anti-nutrients and their effect on the human health. 3. Investigate the extent to which a-amylase inhibitors are capable of interfering with the digestive process ofhumans on consumption ofAmadumbe. 4. Extract beta-sitosterol and/or gamma-sitosterol from Amadumbe to feed rats and do full investigation on effect of the beta-sitosterol on glucose absorption which could be beneficial in diabetes and obesity. 236

2.4 Suggestions for future work<br />

Further studies on Amadumbe are suggested on these lines<br />

1. To extract and partially characterize other anti-nutritional factors in Amadumbe tubers.<br />

2. Studies on the properties ofthese anti-nutrients and their effect on the human health.<br />

3. Investigate the extent to which a-amylase inhibitors are capable of interfering with the<br />

digestive process ofhumans on consumption ofAmadumbe.<br />

4. Extract beta-sitosterol and/or gamma-sitosterol from Amadumbe to feed rats and do full<br />

investigation on effect of the beta-sitosterol on glucose absorption which could be<br />

beneficial in diabetes and obesity.<br />

236

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