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Wyniki wskazały na wybitnie znamienną poprawę indeksu WOMAC (p=0.002), zaś testu Lequesne na granicy<br />

istotności (p=0.05), a testowy poziom prawdopodobieństwa dla korelacji między CTX-II/Kr a indeksem WOMAC<br />

wyniósł p=0.058.<br />

Wniosek: Raloksyfen podawany kobietom przez 12 miesięcy spowodował zmniejszenie degradacji chrząstki przy<br />

równoczesnej poprawie klinicznej mierzonej indeksami WOMAC, i w mniejszym stopniu, indeksem Lequesne.<br />

Przemawia to za przeciwartrotycznym działaniem raloksyfenu.<br />

Piśmiennictwo: 1. Daniluk S., Badurski J., z wsp. XIII Zjazd PTOA i PFO Kraków 2005. 2. Bellamy N: WOMAC<br />

osteoarthritis index.University of Western Ontario,1995. 3. Lequesne M.: Semin Arthritis Rheum 1991,20:48.<br />

P41<br />

SIGNIFICANT IMPROVEMENT OF WOMAC AND LEQUESNE INDICES AFTER 1-YEAR RALOXIFENE<br />

TREATMENT IN WOMEN WITH OSTEOPENIA AND KNEE OSTEOARTHRITIS<br />

Badurski J.E., 1 Daniluk S., Holiczer W., 2 Dobreńko A., Nowak N., Jeziernicka E.<br />

1 Centrum Osteoporozy i Chorób Kostno-Stawowych w 15-461 Białymstoku, ul. Waryńskiego 6/2, Białystok, Poland<br />

2 Politechnika Białostocka, Wydział Elektryczny, Zakład Aparatury Medycznej, Białystok, Poland<br />

Keywords: knee osteoarthritis, raloxifene<br />

(English version of the abstract not submitted)<br />

P42<br />

SYNOVITIS IN KNEE OSTEOARTHRITIS - ULTRASOUND AND CLINICAL STUDY<br />

Milutinovic S.R., Zlatkovic-Svenda M.I.<br />

Institute of Rheumatology, Belgrade, Serbia and Montenegro<br />

Objectives<br />

1. To determine the frequency of clinical synovitis and synovitis using ultrasound (US) imaging in patients with knee<br />

osteoarthritis (KO) 2. To correlate ultrasound findings of synovitis with disease duration, US cartilage thickness, VAS<br />

and body-mass index (BMI) in patients with KO.<br />

Method<br />

Patients with KO (70 joints) underwent a detailed clinical assessment by two rheumatologists, and also were scanned<br />

by one ultrasonographist, who evaluated synovitis of suprapatelar recessus and Baker's cyst, as well as cartilage<br />

thickness. Patological US findings of synovitis was classified as effusion with synovial hypertrophy and effusion<br />

without synovial hypertrophy. Cartilage thickness was classified as normal or reduced. Computer statistical program<br />

SPSS 10.0 was used to calculate the data (Wilcoxon test and Spearman correlation).<br />

Results<br />

The study involved 55-f and 15-m, mean age 60,56± 13,01 years, an average disease duration was 7,42 years. Clinical<br />

synovitis was identified in 19 (27,14 %) joints. US detected: synovitis in 59 (84,28 %) joints without synovial<br />

hypertrophy, while synovial hypertrophy was present in 4 (5,71 %). Baker's cyst enlargement was clinically found in 7<br />

(10%) joints. US verificated Baker's cyst enlargement without synovial hypertrophy in 32 (45,7 %), with synovial<br />

hypertrophy in 9 (12,86 %) joints and cyst rupture was found in 1 (1,4 %) joint, which makes statistically significant<br />

difference between these findings (p

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