316 Rubin BS, Barfield RJ (1983b) Progesterone in the ventromedial hypothalamus facilitates estrous behavior in ovariectomized, estrogen-primed rats. Endocrinology 113:797–804. <strong>Sá</strong> SI, Ma<strong>de</strong>ira MD (2005a) Estrogen modulates the sexually dimorphic synaptic connectivity of the ventromedial nucleus. J Comp Neurol 484:68–79. <strong>Sá</strong> SI, Ma<strong>de</strong>ira MD (2005b) Neuronal organelles and nuclear pores of hypothalamic ventromedial neurons are sexually dimorphic and change during the estrus cycle in the rat. Neuroscience 133:919–924. Santollo J, Wiley MD, Eckel LA (2007) Acute activation of ER <strong>de</strong>creases food intake, meal size, and body weight in ovariectomized rats. Am J Physiol Regul Integr Comp Physiol 293:2194–2201. Segarra AC, McEwen BS (1991) Estrogen increases spine <strong>de</strong>nsity in ventromedial hypothalamic neurons of peripubertal rats. Neuroendocrinology 54:365–372. Shughrue PJ, Merchenthaler I (2001) Distribution of estrogen receptor immunoreactivity in the rat central nervous system. J Comp Neurol 436:64–81. Shughrue PJ, Bushnell CD, Dorsa DM (1992) Estrogen receptor messenger ribonucleic acid in female rat brain during the estrous cycle: a comparison with ovariectomized females and intact males. Endocrinology 131:381–388. Shughrue PJ, Lane MV, Merchenthaler I (1997a) Regulation of progesterone receptor messenger ribonucleic acid in the rat medial preoptic nucleus by estrogenic and antiestrogenic compounds: an in situ hybridization study. Endocrinology 138:5476–5484. 50 S. I. <strong>Sá</strong> et al. / Neuroscience 162 (2009) 307–316 (Accepted 24 April 2009) (Available online 3 May 2009) Shughrue PJ, Lane MV, Merchenthaler I (1997b) Comparative distribution of estrogen receptor- and - mRNA in the rat central nervous system. J Comp Neurol 388:507–525. Simerly RB, Swanson LW (1988) Projections of the medial preoptic nucleus: a Phaseolus vulgaris leucoagglutinin anterogra<strong>de</strong> tracttracing study in the rat. J Comp Neurol 270:209–242. Simerly RB, Young BJ (1991) Regulation of estrogen receptor messenger ribonucleic acid in rat hypothalamus by sex steroid hormones. Mol Endocrinol 5:424–432. Simerly RB, Chang C, Muramatsu M, Swanson LW (1990) Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: an in situ hybridization study. J Comp Neurol 294:76–95. Small JV (1968) Measurement of section thickness. In: Proceedings 4th European Congress of Electron Microscopy, Vol. 1 (Bocciarelli DS, ed), p 609. Roma: Tipografia Poliglotta Vaticana. Sterio DC (1984) The unbiased estimation of number and sizes of arbitrary particles using the disector. J Microsc 134:127–136. Turcotte JC, Hunt PJB, Blaustein JD (2005) Estrogenic effects of zearalenone on the expression of progestin receptors and sexual behavior in female rats. Horm Behav 47:178–184. Walf AA, Ciriza I, Garcia-Segura LM, Frye CA (2008) Antisense oligo<strong>de</strong>oxynucleoti<strong>de</strong>s for estrogen receptor- and attenuate estradiol’s modulation of affective and sexual behavior, respectively. Neuropsychopharmacology 33:431–440. Wu TJ, Glucksman MJ, Roberts JL, Mani SK (2006) Facilitation of lordosis in rats by a metabolite of luteinizing hormone releasing hormone. Endocrinology 147:2544–2549.
Role of neural afferents as mediators of estrogen effects on the hypothalamic ventromedial nucleus IIIIIIIIVVVVVVVV........ 51
- Page 1:
Susana Isabel Ferreira da Silva de
- Page 5:
Esta investigação foi realizada n
- Page 9 and 10:
Corpo Catedrático da Faculdade de
- Page 11:
Doutor Manuel Machado Rodrigues Gom
- Page 15 and 16:
AGRADECIMENTOS Em 2001, por sugest
- Page 17: ÍNDICE ITRODUÇÃO 1 TRABALHOS 15
- Page 21 and 22: Acção dos estrogénios no sistema
- Page 23 and 24: O núcleo ventromedial do hipotála
- Page 25 and 26: ventral e sistema mesencefálico de
- Page 27 and 28: 1991). São, no entanto, menos clar
- Page 29: o objectivo de aquilatar se as dose
- Page 33: TRABALHOS 15
- Page 37 and 38: Neuroscience 133 (2005) 919-924 NEU
- Page 39 and 40: enclosed by the Golgi complex (Fig.
- Page 41 and 42: Fig. 4. Graphic representation of t
- Page 43: Estrogen modulates the sexually dim
- Page 46 and 47: SYNAPTIC PLASTICITY IN THE VM NUCLE
- Page 48 and 49: SYNAPTIC PLASTICITY IN THE VM NUCLE
- Page 50 and 51: SYNAPTIC PLASTICITY IN THE VM NUCLE
- Page 52 and 53: SYNAPTIC PLASTICITY IN THE VM NUCLE
- Page 54 and 55: SYNAPTIC PLASTICITY IN THE VM NUCLE
- Page 56 and 57: SYNAPTIC PLASTICITY IN THE VM NUCLE
- Page 59 and 60: Neuroscience 162 (2009) 307-316 EFF
- Page 61 and 62: ml) and chloral hydrate (40 mg/ml)
- Page 63 and 64: Table 1. Serum estradiol and proges
- Page 65 and 66: (Frankfurt and McEwen, 1991a; Segar
- Page 67: Canteras NS, Simerly RB, Swanson LW
- Page 72 and 73: 2 1989; Krettek and Price, 1978), b
- Page 74 and 75: 4 rats. As expected, treatment of o
- Page 76 and 77: 6 estrogen-induced synapse formatio
- Page 78 and 79: 8 4.3. Hormonal determinations Bloo
- Page 80 and 81: 10 estrogen treatment. Brain Res. 2
- Page 83: DISCUSSÃO GERAL 65
- Page 86 and 87: Apesar de nas fêmeas os neurónios
- Page 88 and 89: influências excitatórias que sobr
- Page 90 and 91: estrogénios promovam a formação
- Page 93: CONCLUSÕES 75
- Page 97: REFERÊNCIAS 79
- Page 100 and 101: Brown TJ, Clark AS, MacLusky NJ. Re
- Page 102 and 103: Griffin GD, Flanagan-Cato LM. Estra
- Page 104 and 105: Luiten PG, ter Horst GJ, Steffens A
- Page 106 and 107: Ribeiro AC, Sawa E, Carren-LeSauter
- Page 108 and 109: Voskuhl RR. Hormone-based therapies
- Page 111: Com os resultados constantes desta
- Page 115: The studies incorporated in the pre
Change language