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Complementary Alternative Cardiovascular Medicine

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78 <strong>Alternative</strong> <strong>Cardiovascular</strong> <strong>Medicine</strong><br />

Fig. 3. Relationship between change in dietary cholesterol (0–1100 mg/d) and<br />

change in cholesterol concentration. Source: Institute of <strong>Medicine</strong> of the<br />

National Academies. Dietary Reference Intakes for Energy, Carbohydrate,<br />

Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids. Washington<br />

DC, National Academies Press, 2002.<br />

UNSATURATED FATTY ACIDS<br />

The evidence is convincing to support the recommendation to decrease<br />

saturated fat, trans fat, and cholesterol to reduce CVD risk. There is provocative<br />

and compelling new evidence that shows beneficial effects of<br />

unsaturated fatty acids. The emergence of this new appreciation that<br />

unsaturated fatty acids decrease CVD risk has been an impetus for revising<br />

our dietary messages regarding unsaturated fat, and, in turn, total fat.<br />

Critical to this new approach is that unsaturated fats be included in a<br />

nutritionally adequate diet at a level that meets energy needs and elicits<br />

the expected health effects. Consequently, the diet message has<br />

transitioned from a low-fat to a moderate-fat recommendation to ensure<br />

adequate intake of unsaturated fatty acids.<br />

MONOUNSATURATED FATTY ACIDS<br />

MUFAs decrease total cholesterol and LDL cholesterol when substituted<br />

for SFA. When MUFAs replace SFA calories, plasma triglycerides

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