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Complementary Alternative Cardiovascular Medicine

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222 <strong>Alternative</strong> <strong>Cardiovascular</strong> <strong>Medicine</strong><br />

POSITIVE CLINICAL STUDIES<br />

There have been several well-designed randomized studies of the<br />

safety and effectiveness of homeopathy for specific symptoms/illnesses.<br />

Reilly et al. showed that homeopathic preparations (via both symptomatic<br />

and immunotherapy mechanisms) can reduce the severity and<br />

duration of allergic asthma (22)—individual study, with greater p value<br />

(increased from 0.003 to 0.0004) when results of 38 patients were combined<br />

with two other similar studies—hay fever (23), and allergic rhinitis<br />

(24). This last study found homeopathy’s nasal effects to be similar<br />

to topical steroids.<br />

Jacobs et al. published three clinical studies: two showed significant<br />

lessening of diarrhea’s effects in children compared to placebo (25,26).<br />

The other examined acute otitis media, and these results showed significant<br />

lessening in symptoms and (nonsignificant) lessening of treatment<br />

failures (27).<br />

A Harvard study in 1999 showed improvement in mild traumatic<br />

brain injury (28).<br />

A German study showed homeopathy’s equivalence to beta-histine in<br />

treating vertigo (29).<br />

Vickers’ meta-analysis of seven studies showed that the remedy<br />

oscillococcinum reduced the duration of influenza symptoms but not prevention<br />

(30)—although the overall quality of the studies was criticized.<br />

NEGATIVE CLINICAL STUDIES<br />

A common complaint of most authors of homeopathy meta-analyses<br />

is methodological flaws (31). For example, the Cochrane review of<br />

asthma studies, which contradicts Reilly, concluded that design flaws<br />

precluded comment on efficacy (32). Better design with larger studies<br />

unencumbered by belief systems are urgently needed (33).<br />

At this point, there are several well-designed studies that show no<br />

effect with homeopathy on specific conditions. These include:<br />

The use of arnica in surgery (meta-analysis of eight studies) (34) and<br />

postoperative hematomas (35).<br />

Migraine headaches were not helped with homeopathy in three different<br />

studies (36–38).<br />

Two meta-analyses of overall effects compared to placebo that conclude<br />

that the quality of the homeopathic studies cannot support its<br />

superiority over placebo (20,21).<br />

One issue that splits mainstream medicine and the homeopathic community<br />

alike is which remedies to use in homeopathic studies. Traditionally<br />

in homeopathy, each individual receives a remedy that is highly

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