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Complementary Alternative Cardiovascular Medicine

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Chapter 9 /Prayer and CVD 141<br />

that healing prayer was associated with some degree of therapeutic benefit.<br />

The conclusion that these findings supported was that more and<br />

better designs of prayer studies were indicated based on the literature<br />

available to date.<br />

PROSPECTIVE RANDOMIZED TRIALS<br />

OF INTERCESSORY PRAYER IN CARDIOLOGY<br />

Only four prospective randomized, controlled clinical trials of intercessory<br />

prayer have been reported in cardiology populations (10–13).<br />

Two additional multicenter prospective randomized trials have completed<br />

enrollment of patients after bypass surgery and in patients<br />

underoing percutaneous coronary intervention. Neither of these studies<br />

has yet been reported.<br />

The first reported study investigated the role of distant prayer in the<br />

coronary care unit (CCU) and was published in 1988 (10). In this study,<br />

all patients admitted to the CCU of San Francisco General Hospital were<br />

approached to enter the study. Patients who consented (393 of 450<br />

approached) were randomized to receive standard care or standard care<br />

plus intercessory prayer. Each patient in the intervention group was<br />

prayed for by three to seven intercessors, who were all “born-again<br />

Christians (according to the Gospel of John 3:3).” The intercessors were<br />

told the patient’s first name, general condition, diagnosis, and updates on<br />

their condition. The intercessors prayed daily for the patients until they<br />

were discharged from the hospital. Multiple clinical outcomes were measured,<br />

and each patient’s hospital course was graded as “good,” “intermediate,”<br />

or “bad,” depending on morbidity. This was done in a blinded<br />

fashion regarding patient group assignment.<br />

Of the patients receiving prayer, 85% had a “good” hospital course,<br />

as compared to 73% in the control group. Fourteen percent of the prayer<br />

treatment group had a “bad” hospital course, as compared to 22% of the<br />

control group. These comparisons reached statistical significance with<br />

a p value of

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