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Diapositiva 1

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H 0: variable selective pressure but NO positive selection (M1a)<br />

H 1: variable selective pressure with positive selection (M2a)<br />

Likelihood ratio test (LRT)<br />

2Δl = 2 (l 1-l 0) χ 2 distribution<br />

SE:<br />

• IL MODELLO M2a SI<br />

ADATTA MEGLIO AI DATI<br />

• IL VALORE DI ω STIMATO<br />

E’ >1 PER LA CLASSE DI<br />

SITI p 2<br />

UNA PROPORZIONE<br />

DI SITI PARI A p2 E’<br />

SOTTOPOSTA A<br />

SELEZIONE<br />

POSITIVA

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