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SCIENTIFIC REPORT 2010 - 2011 - IOV

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FOREWORD 5<br />

THE INSTITUTE 9<br />

Chief Officer Address 13<br />

The <strong>IOV</strong> Governance 16<br />

CLINICAL ACTIVITY ORGANIZATION 19<br />

Chief Medical Officer Report 21<br />

Clinical Activity Data 24<br />

Multidisciplinary Groups 28<br />

THE DEPARTMENTS 31<br />

Department of Clinical Oncology 33<br />

Clinical Oncology 1 34<br />

Clinical Oncology 2 46<br />

Evaluation and Introduction of New Drugs<br />

in Cancer Therapy 54<br />

Department of Surgery 57<br />

Surgical Oncology 58<br />

Breast Surgery 64<br />

Melanoma and Soft Tissue Tumors 68<br />

Diagnostic and Operative Endoscopy 76<br />

Anesthesiology 82<br />

Department of Imaging, Radiology and Pathology 89<br />

Radiology 90<br />

Breast Imaging 96<br />

Pathology 104<br />

Department of Radiotherapy and Nuclear Medicine 107<br />

Radiotherapy and Nuclear Medicine 108<br />

Medical Physics 120<br />

Department of Experimental, Laboratory and<br />

Translational Oncology 127<br />

Immunology and Molecular Oncology 128<br />

Hereditary Endrocrine Cancer Unit 154<br />

CONTENTS<br />

CONTENTS<br />

3<br />

Department of Services 161<br />

Pharmacy 162<br />

Cardiology 168<br />

Psycho-Oncology 172<br />

Tumor Registry 178<br />

THE RESEARCH 185<br />

Scientific Director Address 187<br />

General Considerations 188<br />

Scientific Directorate Organization 191<br />

SWOT Analysis 195<br />

Research: Input and Output 197<br />

Clinical Trials and Biostatistics Unit 202<br />

Strategic Scientific Options 209<br />

Pharmacogenomics 212<br />

Cancer Stem Cells 214<br />

RESEARCH ACTIVITY <strong>REPORT</strong> 217<br />

Line 1 - Tumor Epidemiology and Prevention 218<br />

Introduction 218<br />

Workflow Project List 219<br />

Line 2 - Mechanisms of Cancerogenesis 220<br />

Introduction 220<br />

Workflow Project List<br />

Line 3 - Instrumental and Molecular Approaches<br />

221<br />

for Diagnosis, Staging and Follow-Up 222<br />

Introduction 222<br />

Workflow Project List<br />

Line 4 - Innovative Therapeutic Approaches:<br />

223<br />

Chemotherapy, Radiotherapy and Surgery 226<br />

Introduction 226<br />

Workflow Project List 227

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