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Neonicotinoid Pesticides and Bees - The Food and Environment ...

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Insecticide<br />

Clothianidin<br />

Imidacloprid<br />

Thiacloprid<br />

Thiamethoxam<br />

Table 10: Oral toxicity of combinations (from Defra project PS2368)<br />

LD 50<br />

(µg/bee)<br />

(range)<br />

0.00739<br />

(0.00607-<br />

0.00903)<br />

0.536<br />

(0.339-<br />

1.184)<br />

22.59<br />

(16.39-<br />

37.42)<br />

0.0112<br />

(0.00915-<br />

0.0135)<br />

LD 50<br />

(µg/bee)<br />

0.00441<br />

1.180<br />

54.65<br />

0.0103<br />

+ Flusilazole (0.358 µg/bee) + Myclobutanil (0.161 µg/bee) + Propiconazole (0.224 µg/bee) + Tebuconazole (0.447 µg/bee)<br />

95% CL<br />

0.00267-<br />

0.00762<br />

0.6094-<br />

5.878<br />

25.88-<br />

852.8<br />

0.00801-<br />

0.0136<br />

synergism<br />

ratio<br />

Synergism ratio = . Insecticide LD50 .<br />

Insecticide + fungicide LD50<br />

LD 50<br />

(µg/bee)<br />

1.68 0.00597<br />

0.45 1.075<br />

0.41 25.67<br />

1.09 0.00742<br />

95% CL<br />

0.00493-<br />

.000732<br />

0.5667-<br />

4.426<br />

synergism<br />

ratio<br />

LD 50<br />

(µg/bee)<br />

1.24 0.00572<br />

0.50 1.501<br />

<strong>Neonicotinoid</strong> pesticides <strong>and</strong> bees Page 38 of 133<br />

Report to Syngenta Ltd<br />

19.01-<br />

40.70<br />

0.00448-<br />

0.01123<br />

0.88 47.01<br />

95%<br />

CL<br />

0.00467-<br />

0.00710<br />

0.6972-<br />

14.44<br />

27.45-<br />

166.1<br />

synergism<br />

ratio<br />

LD 50<br />

(µg/bee)<br />

1.29 0.00389<br />

0.36 0.893<br />

0.48 36.19<br />

1.51 0.00830 - 1.35 0.00852<br />

95% CL<br />

0.00305-<br />

0.00489<br />

0.438-<br />

14.50<br />

20.99-<br />

134.1<br />

0.00688-<br />

0.01037<br />

synergism<br />

ratio<br />

1.90#<br />

0.59<br />

0.62<br />

1.31

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