semmelweis university 2 0 1 2 / 2 0 1 3
semmelweis university 2 0 1 2 / 2 0 1 3 semmelweis university 2 0 1 2 / 2 0 1 3
PHARMACOGNOSY Director: Dr. Anna Blázovics Lecturer: Prof. Ágnes Kéry Tutor: Dr. Andrea Balázs First Semester SEMMELWEIS UNIVERSITY / FACULTY OF PHARMACY Lectures (2 hours per week) Practicals (4 hours per week) Terpenoids: biogenetic generalities. Essential oil containg drugs (Lamiaceae, Classification. Regular and irregular monoterpenes, Asteraceae, Apiaceae) sesquiterpenes. Essential oils. Lamiaceae containing essential oils. Methods in essential oil analyses (GC, Anise-flavored essential oils. TLC). Steam distillation of essential oils. Asteraceae containing essential oils. Iridoids. Chief iridoid containing drugs. Bitter substances of plants. Sesquiterpene lactones. Chief drugs containing Classification, reactions, bitter value. sesquiterpence lactones. Diterpenes. Diterpene-containing drugs of potential Saponins and chief saponin drugs. interest. Triterpenes und steroids. Biosynthesis, classification. Saponins. Biological and pharmacological interest. Methods used in the identification Chief saponin containing drugs. and quality control of saponins. Adaptogenes. Ginseng, Siberian Ginseng. Cardiac glycosides. Structures, chief vegetable drugs. Cardioactive glycosides and chief drugs. Starting materials for steroid hormone semisynthesis. Methods used in the analyses of Other significant steroids and triterpenes. cardioactive glycosides. Carotenoids. Chief carotenoid-containing drugs. Alkaloids in general. Protoalkaloids and their chief drugs. Tropane, piridine and piperidine alkaloid containing drugs. Alkaloids derived from ornithine and lysine. Quantitative assays in alkaloid chemistry Tropane-, pyrrolizidine-, quinolizidine-, indolizidine-, (titration) piperidine alkaloids and their drugs. Alkaloids derived from nicotinic acid. Quinoline, isoquinoline and morphine Alkaloids derived from phenylalanine and tyrosine: group alkaloids, their chief drugs. phenethylamines-, isoquinolines-, benzyltetraisoquinoline-, phenethylisoquinoline alkaloids and their drugs. Alkaloids derived from phenylalanine and tyrosine: Methods in alkaloid chemistry: TLC, TLC- Morphinan alkaloids. densitometry, spectrophotometry. Alkaloids derived from tryptophan: ergotine alkaloids, Indol, purine alkaloids. Alkaloids with monoterpenoid indole alkaloids and chief drugs. miscellaneous structure. Chief drugs. Alkaloids derived from anthranilic acid: quinoline, Methods in alkaloid chemistry: Column quinazoline alkaloids. Alkaloids derived from histidine: chromatography. imidazol alkaloids. Terpenoid alkaloids. Purine bases. Practical examination. Alkaloids with miscellaneous structure. Vitamins and vitamin containing drugs. Practical examination. Plants in complementary and traditional systems of medicine. Plants in prevention, Funcional foods Faculty of Pharmacy 453
SEMMELWEIS UNIVERSITY / FACULTY OF PHARMACY 454 PHARMACOLOGY AND TOXICOLOGY Department of Pharmacodynamics Course Director: Prof. Dr. György Bagdy Tutor: Dr. Tamás Tábi First Semester General principles of drug action : receptor theory General principles of drug action The fate of drugs in the body Drug metabolism Pharmacokinetics Factors influencing the drug effect Basics of clinical pharmacology Chemical neurotransmission Pharmacology of ANS Chemical neurotransmission in the CNS General anaesthetic agents Narcotic analgesics: opioids Drug abuse and drug dependence Anxiolytic and hypnotic drugs Drugs used in affective disorders Antipsychotic drugs CNS stimulants and appetite control Antiepileptics and excitatory amino acid neurotransmitters Neurodegenerative disorders Local anaesthetics Drugs acting on striated and smooth muscle Drug interactions. Adverse effects Toxicology Second Semester Histamine and antihistamines. Glucocorticoids Immunopharmacology Non-steroidal anti-inflammatory drugs Antirheumatoid drugs Basic principles of antibiotic chemotherapy Sulphonamides. Fluoroquinolones. Beta-lactam antibiotics Tetracyclines. Chloramphenicol. Macrolides Aminoglycosides. Minor antibiotics Antiprotozoal and antihelminthic drugs Antifungal drugs Antimycobacterial and antiviral drugs Cancer chemotherapy I. Cancer chemotherapy II. Pharmacotherapy of heart failure
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PHARMACOGNOSY<br />
Director: Dr. Anna Blázovics<br />
Lecturer: Prof. Ágnes Kéry<br />
Tutor: Dr. Andrea Balázs<br />
First Semester<br />
SEMMELWEIS UNIVERSITY / FACULTY OF PHARMACY<br />
Lectures (2 hours per week) Practicals (4 hours per week)<br />
Terpenoids: biogenetic generalities. Essential oil containg drugs (Lamiaceae,<br />
Classification. Regular and irregular monoterpenes, Asteraceae, Apiaceae)<br />
sesquiterpenes. Essential oils.<br />
Lamiaceae containing essential oils. Methods in essential oil analyses (GC,<br />
Anise-flavored essential oils. TLC). Steam distillation of essential oils.<br />
Asteraceae containing essential oils.<br />
Iridoids. Chief iridoid containing drugs. Bitter substances of plants.<br />
Sesquiterpene lactones. Chief drugs containing Classification, reactions, bitter value.<br />
sesquiterpence lactones.<br />
Diterpenes. Diterpene-containing drugs of potential Saponins and chief saponin drugs.<br />
interest. Triterpenes und steroids.<br />
Biosynthesis, classification.<br />
Saponins. Biological and pharmacological interest. Methods used in the identification<br />
Chief saponin containing drugs. and quality control of saponins.<br />
Adaptogenes. Ginseng, Siberian Ginseng.<br />
Cardiac glycosides. Structures, chief vegetable drugs. Cardioactive glycosides and chief drugs.<br />
Starting materials for steroid hormone semisynthesis. Methods used in the analyses of<br />
Other significant steroids and triterpenes. cardioactive glycosides.<br />
Carotenoids. Chief carotenoid-containing drugs.<br />
Alkaloids in general. Protoalkaloids and their chief drugs. Tropane, piridine and piperidine alkaloid<br />
containing drugs.<br />
Alkaloids derived from ornithine and lysine. Quantitative assays in alkaloid chemistry<br />
Tropane-, pyrrolizidine-, quinolizidine-, indolizidine-, (titration)<br />
piperidine alkaloids and their drugs.<br />
Alkaloids derived from nicotinic acid. Quinoline, isoquinoline and morphine<br />
Alkaloids derived from phenylalanine and tyrosine: group alkaloids, their chief drugs.<br />
phenethylamines-, isoquinolines-,<br />
benzyltetraisoquinoline-, phenethylisoquinoline<br />
alkaloids and their drugs.<br />
Alkaloids derived from phenylalanine and tyrosine: Methods in alkaloid chemistry: TLC, TLC-<br />
Morphinan alkaloids. densitometry, spectrophotometry.<br />
Alkaloids derived from tryptophan: ergotine alkaloids, Indol, purine alkaloids. Alkaloids with<br />
monoterpenoid indole alkaloids and chief drugs. miscellaneous structure. Chief drugs.<br />
Alkaloids derived from anthranilic acid: quinoline, Methods in alkaloid chemistry: Column<br />
quinazoline alkaloids. Alkaloids derived from histidine: chromatography.<br />
imidazol alkaloids. Terpenoid alkaloids.<br />
Purine bases. Practical examination.<br />
Alkaloids with miscellaneous structure.<br />
Vitamins and vitamin containing drugs. Practical examination.<br />
Plants in complementary and traditional systems<br />
of medicine.<br />
Plants in prevention, Funcional foods<br />
Faculty of<br />
Pharmacy<br />
453
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