semmelweis university 2 0 1 2 / 2 0 1 3

PHARMACEUTICAL MICROBIOLOGY
Program director: Prof. Dr. Éva Ádám
Tutor: Dr. Zsuzsanna Csukás
Second Semester
SEMMELWEIS UNIVERSITY / FACULTY OF PHARMACY
Lectures (3 hours per week) Practices (2 hours per week)
Introduction. Short history, subject and aim of Microbiology. Introduction to basic microbiology. Laboratory
Occurence and importance of microorganisms in the nature. rules. Morphology of bacteria (Microscopic
General microbiology. Microbial genetic. examinations I.)
Principles and practice of sterilization. Sterile pharmaceutical Morphology of bacteria. Staining procedures
products. Sterility control. (Microscopic examinations II.)
Contamination of non-sterile pharmaceuticals in hospital and Methods for cultivation of bacteria. Examination
community environment.
Chemical disinfectants, antiseptics and preservatives.
of biochemical activity of microorganisms I.
Types of antibiotics and synthetic antimicrobial agents. Colony morphology of bacteria. Examination
Mechanisms of action of the antibiotics. Bacterial resistance
to antibiotics. Interactions
of biochemical activity of microorganisms II.
Principles of microbial pathogenicity and epidemiology. Laboratory procedures of sterilization and
Immunity to microbes. Active and passive immunization. disinfection.
Bacteria causing purulent diseases.
Bacteria causing enteric diseases.
Antibiotic susceptibility of bacteria.
Causative agents of respiratory tract. Aerobic and anaerobic In vitro antigen-antibody reactions
endospore forming bacteria. Other anaerobic microbes. (serological reactions).
Spirochetes. Rickettsiae. Chlamydia.Mycoplasmas Bacteria causing purulent diseases
Parasitology (parasites and helminths). Bacteria of the respiratory tract I.
Causative agents of human mycosis and their therapy.
General virology. Interactions between viruses and the
human host.
Bacteria of the respiratory tract II.
Characterization of virus Families causing human diseases. Normal flora and pathogens of the
Respiratory pathogen viruses and the most important diseases.
Enteric viruses and diseases caused by them.
gastrointestinal tract.
Hepatitis viruses. Aerobic and anaerobic endospore forming
Arthropode-borne viruses and diseases caused by them.
Other important virus caused diseases.
Bacteria. Spirochetes. Chlamydiae.
Slow virus infections. Conventional and non-conventional Morphology and cultivation of human pathogen
agents. Prions. AIDS. The role of viruses in carcinogenesis. Fungi. Medically important protozoons.
Antiviral chemotherapy. Interferon.
Immunity to viral infections.
Medically important helminths.
Application of microorganisms in the pharmaceutical sciences. Cultivation of viruses. Virus-cell interactions.
Production of therapeutically useful substances by recombinant
DNA technology. New ways in vaccine production.
Bacteriophages.
The manufacture and quality control of immunological products. Medical virology. The most important viral
Importance of nosocomial infections. Factory and hospital
hygiene and good manufacturing practice.
diseases:prevention and therapy.
In the course of laboratory practices, the students of Faculty of Pharmacy become acquainted with the
most important methods used for microbiological diagnosis of human pathogen bacteria, viruses and
parasites.
Note: The maximum number of the absences in the semester is 3. More than 3 absences invalidate
the semester.
During the semester two midterms should be passed.
Practical course grade. Final examination.
Faculty of
Pharmacy
443