semmelweis university 2 0 1 2 / 2 0 1 3

Lectures (2 hours per week) Practicals
Microsomal drug metabolism. Microsomal mono- Seminar: gene therapy
oxygenase system: induction of cytochrome P-450.
Conjugation reactions in detoxification.
Mechanism of the regulation of biomechanical pathways
by hormones. Biochemistry of the hormonal action.
Receptors, classification of receptors. The ion channels.
Calcium homeostasis.
The signal transduction: the G-proteins, role of the
adenylate cyclase and phophoinositol system in signal
transduction. The proteine kinases and phosphorylation
of specific proteins.
Interaction of receptors and hormones. Mechanism of Consultation.
neurotransmission. The cholinerg and adrenerg transmission.
The insulin and steriodreceptors.
COLLOID CHEMISTRY
Tutor: Dr. Ferenc Csempesz
First Semester
Practice (2 hours per week)
SEMMELWEIS UNIVERSITY / FACULTY OF PHARMACY
Surface and interfacial tensions
Measurement of the surface, the tension of aqueous surfactant solutions.
Determination of oil/water and oil/ solution interfacial tensions.
Adsorption at interfaces
Determination of vapour adsorption isotherm by gravimetric method.
Adsorption from solution; determination of adsorption isotherm for methylene blue on
cellulose.
Wetting of solid surfaces
Determination of contact angles. Flotation of kaolin suspensions by cationic
surfactants, characterization of the wetting properties of kaolin particles.
Stability of colloidal dispersions
Determination of critical coagulation concentration of electrostatically stabilized sols.
Flocculation and stabilization of sols by uncharged polymers and polyelectrolytes.
Electrokinetic phenomena
Measurement of electrophoretic mobility by moving boundary method, determination of
zeta potential.
Separation to components of a dye mixture by zone electrophopresis.
Suspensions and emulsions
Determination of particle size distribution by Andreasen pipette.
Determination of apparent viscosity of concentrated suspensions, investigation of
thyxotropy. Preparation of emulsion by dispersion method, determination of the type of
emulsion. Measurement of the viscosity of concentrated emulsions by rotational
viscometric method.
Faculty of
Pharmacy
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