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PHARMACEUTICAL BOTANY Department of Plant Anatomy Tutor: Dr. Gábor Kovács First Semester SEMMELWEIS UNIVERSITY / FACULTY OF PHARMACY Weeks Lectures (1 hour per week) Practicals (3 hours per week) 1 Embryo development. The root apex, primary Germination, seedlings. Plants structure of roots. Root modifications representing fam.: Fabaceae, Brassicaceae 2 The shoot apex. The primary structure of Roots. Plants representing fam.: stems. Stemroot connection. Apiaceae, Euphorbiaceae. 3 Secondary growth of roots and stems. Stems I. Plants representing fam.: Solanaceae, Lamiaceae 4 Development and anatomy of leaves. Stems II. Plants representing fam.: Adaptations to the environment. Shoot Asteraceae modifications. 5 The movement of water in plants. Mineral 1. Test Work: nutrition. Transport of assimilates. Plants representing fam.: Cannabaceae 6 Initiation and anatomy of flowers. Sporo- Woddy stems (Gymnosperms, Angiosperms.) and gametogenesis in angiosperms. Fruits The fungi (introduction). I.Test and seed. Work on the knowledge of medicinal plants 7 Control of growth and development. The Fungi I. 8 Mycophyta, Bryophyta, Pteridophyta, The Fungi II. Gymnospermatophyta 9 Angiospermatophyta: Magnoliidae 2. Test Work: Fungi Preparing a cleared specimen 10 Angiospermatophyta: Hamamelididae, Leaf and flower anatomy Caryophyllidae 11 Angiospermatophyta: Rosidae Morphology and anatomy of the seed 2. Test Work on the knowledge of medicinal plants. 12 Angiospermatophyta: Dilleniidae Morphology and anatomy of the fruit. 13 Angiospermatophyta: Asteridae 3. Test Work: woody stems, leaf, flower, seed, fruit. 14 Angiospermatophyta: Monocotyledoneae Consultation, questioning, finishing the practicals. Visit in the Botanical Garden of Eötvös Loránd University to learn taxonomy of higher plants. Field trip (1 day) to learn medicinal plants and fungi in the wild. Handing in of your own herbarium (collection of 30 medicinal plants, pressed and dried, mounted for permanent display with references). Faculty of Pharmacy 425
SEMMELWEIS UNIVERSITY / FACULTY OF PHARMACY 426 BIOCHEMISTRY Department of Medical Biochemistry Lecturer: Dr. György Szabados Tutor: Dr. Attila Ambrus Second Semester Lectures (3 hours per week) Proteins. The amino acids building blocks of proteins. Determination of amino acid composition and primary structure of proteins. Ordered conformations of polypeptide chains. Four levels of protein structure. Determination of secondary and tertiary structure. Oxygen transporting proteins. Myoglobin and hemoglobin. Structure of myoglobin and hemoglobin. Fetal hemoglobin. Molecular pathology of hemoglobin. Purification and characterization of proteins. Separation procedures based on molecular size, solubility differences, electric charge and selective adsorption. Enzymes. Identification of functional groups essential for catalysis. Kinetics of enzyme-catalyzed reactions: The Michaelis-Menten equation. Transformation of the Michaelis-Menten equation. Enzyme inhibition. Regulatory enzymes: allosteric enzymes, covalently modulated regulatory enzymes. Fine mechanism of enzyme action. Three-dimensional structure of chymotrypsin, a serine protease. Mechanism of acetylcholinesterase catalysis. Bioenergetics. Introductory remarks. High energy compounds. Glycolysis. Oxidative decarboxylation of pyruvate Citric acid cycle. Metabolic transport through the mitochondrial membranes. Respiratory chain. Oxidative phosphorylation. Mitochondrial import and export of reductive equivalents. Energetics of glucose oxidation. Pasteur effect. Heat production by the brown adipose tissue. Carbohydrate metabolism. Cellular uptake and production of glucose. Gluconeogenesis. Regulation of glycolysis and gluconeogenesis. Glycogen metabolism. Blood glucose and regulation of glycogenolysis and glycogenesis. Hexose interconversions. Galactosemia and galactosuria. Fructosuria and fructose intolerance. The phosphogluconate oxidative pathway. Significance and regulation of the pentose phosphate pathway. Biosynthesis of hexosamines. Biological role and synthesis of glycoproteins and glycolipids
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PHARMACEUTICAL BOTANY<br />
Department of Plant Anatomy<br />
Tutor: Dr. Gábor Kovács<br />
First Semester<br />
SEMMELWEIS UNIVERSITY / FACULTY OF PHARMACY<br />
Weeks Lectures (1 hour per week) Practicals (3 hours per week)<br />
1 Embryo development. The root apex, primary Germination, seedlings. Plants<br />
structure of roots. Root modifications representing fam.: Fabaceae,<br />
Brassicaceae<br />
2 The shoot apex. The primary structure of Roots. Plants representing fam.:<br />
stems. Stemroot connection. Apiaceae, Euphorbiaceae.<br />
3 Secondary growth of roots and stems. Stems I. Plants representing fam.:<br />
Solanaceae, Lamiaceae<br />
4 Development and anatomy of leaves. Stems II. Plants representing fam.:<br />
Adaptations to the environment. Shoot Asteraceae<br />
modifications.<br />
5 The movement of water in plants. Mineral 1. Test Work:<br />
nutrition. Transport of assimilates. Plants representing fam.: Cannabaceae<br />
6 Initiation and anatomy of flowers. Sporo- Woddy stems (Gymnosperms,<br />
Angiosperms.)<br />
and gametogenesis in angiosperms. Fruits The fungi (introduction). I.Test<br />
and seed. Work on the knowledge of medicinal<br />
plants<br />
7 Control of growth and development. The Fungi I.<br />
8 Mycophyta, Bryophyta, Pteridophyta, The Fungi II.<br />
Gymnospermatophyta<br />
9 Angiospermatophyta: Magnoliidae 2. Test Work: Fungi<br />
Preparing a cleared specimen<br />
10 Angiospermatophyta: Hamamelididae, Leaf and flower anatomy<br />
Caryophyllidae<br />
11 Angiospermatophyta: Rosidae Morphology and anatomy of the seed<br />
2. Test Work on the knowledge<br />
of medicinal plants.<br />
12 Angiospermatophyta: Dilleniidae Morphology and anatomy of the fruit.<br />
13 Angiospermatophyta: Asteridae 3. Test Work: woody stems, leaf,<br />
flower, seed, fruit.<br />
14 Angiospermatophyta: Monocotyledoneae Consultation, questioning, finishing<br />
the practicals.<br />
Visit in the Botanical Garden of Eötvös Loránd University to learn taxonomy of higher<br />
plants. Field trip (1 day) to learn medicinal plants and fungi in the wild. Handing in of your<br />
own herbarium (collection of 30 medicinal plants, pressed and dried, mounted for<br />
permanent display with references).<br />
Faculty of<br />
Pharmacy<br />
425
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