semmelweis university 2 0 1 2 / 2 0 1 3

QUANTITATIVE ANALYTICAL CHEMISTRY
Tutor: Dr. Krisztina Kurin-Csörgei
First Semester
SEMMELWEIS UNIVERSITY / FACULTY OF PHARMACY
Lectures (2 hours per week) Practicals (5 hours per week)
Topic Task
Introduction. Review of some elementary Introduction. Laboratory introduction; Safety and order
concepts. Titrimetric methods of analysis. in the laboratory; The schedule of the
semester; Practical and theoretical
requirements in the semester
Acid-base reactions, repetition of different Calibration Calibration of burette (3-6-9-12 ml);
calculations. Titration curves in acid-base Calibration of pipettes (10, 20 ml)
titration.
End point detection Acidi-Alkalimetry Practicing the use of the laboratory tools;
Acid-base indicators. Determination of sulfuric acid
Standard solutions in acid-base acid Acidi-Alkalimetry Standardization of » 0.1N hydrochloric
titrations and the survey of the
most important methods.
Acid-base titrations in non-aqueous Acidi-Alkalimetry Test I.
solutions. Determination of organic Determinations of hydroxide and
bases in glacial acetic acid. carbonate ions in the presence of each
other
Effects of common ion, pH, complex Acidi-Alkalimetry Potentiometric titration of acetic acid;
formation and redox processes on (Instrumental) Conductometric determination of
precipitation. Betaine hydrochloride
Formation and morphology of precipitates. Acidi-Alkalimetry Indirect determination of sodium
Development and treatment of precipitates. thiosulfate Determination of “Lidocain” in
nonaqueous solution
Important methods in precipitation Acidi-alkalim.; Determination of lactic acid;
gravimetry. Chelatometry Chelatometric determination of lead.
Precipitation titrimetry. Chelatometry Test II.
Determination of calcium and
magnesium ions in mineral water
Complex formation, chelate effect. Chelatometry Determination of copper and zinc in the
Stability constant. Complexometric presence of each other; Determination
and chelatometric titrations. of aluminium in “Aluminium
aceticum tartaricum solutum”
Effect of pH and foraign ligands on Gravimetry Gravimetric determination of sulfate ions
the apparent stability constant. in the form of BaSO4;
(precipitation, preparation of filter)
Chelatometric titrations. Titration Gravimetry; filtration, washing, weighing of BaSO4
curves. Methods of end point detection. Argentometry precipitate; Determination of chloride
ions by Mohr’s method
Types and applicability of EDTA Argentometry Test III.
titrations. Determination of bromide ions by
Volhard’s and Fajans’ methods
Redox reactions and their mechanism. Komplexometry Determination of cyanides by
The redox potential and its calculation. Liebig-Denigees’ Method;
Supplements Supplements
The effect of pH, the complex and Supplements Supplements;
precipitate formations on redox potential. Closing Closing
Redox equilibria.
Faculty of
Pharmacy
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