semmelweis university 2 0 1 2 / 2 0 1 3
semmelweis university 2 0 1 2 / 2 0 1 3 semmelweis university 2 0 1 2 / 2 0 1 3
GENERAL AND ORAL MICROBIOLOGY Department of Medical Microbiology Program Director and tutor: Prof. Dr. Károly Nagy Tutor: Dr. Zsuzsanna Csukás First Semester Lectures (2 hours per week) Practices (2 hours per week) Introduction to microbiology. General bacteriology (morphology, physiology and cultivation of bacteria) Bacterial genetics. Infections and diseases (pathogenesis of bacterial infection, virulence, importance of biofilm formation). Specific and non-specific host defences. Active and passive immunization. Sterilization and disinfection. Antibacterial chemotherapy (mode of actions, resistance, side effects). Gram-positive facultative and obligate anaerobic cocci. Gram-negative facultative ananerobic, microaerophilic and obligate anaerobic cocci and coccobacilli. Gram-positive aerobic and anaerobic rods. Gram-positive spore-forming rods. Gram-negative facultative anaerobic rods. Gram-negative anaerobic rods. Mycobacteria. Rickettsia, Chlamydia. Mycoplasma. Spirochetes. Importance of bacterial infections involving the oral, perioral tissues and salivary glands. Medical importance of fungi (general mycology, chemotherapy of fungal infections). Importance of fungal infections involving the oral and perioral tissues. Protozoa (general characterization and the most important human pathogenic protozoa). Helminths (general characterization and the most important human worms). General properties of viruses. Antiviral chemotherapy. Adeno- and Poxviruses. Important respiratory pathogen viruses. Important enterally transmitted viruses. Hepatitis viruses. Retroviruses (AIDS). Viruses and cancer. SEMMELWEIS UNIVERSITY / FACULTY OF DENTISTRY Introduction to basic microbiology. Microscopic examination of bacteria (staining procedures). Cultivation of aerobic and anaerobic bacteria (culture media, colony morphology of bacteria). Methods used for sterilization and disinfections (physical and chemical possibilities). Antibiotic susceptibility of bacteria In vitro antigen-antibody reactions (serological methods). Gram-positive and -negative cocci and coccobacilli Gram-positive rods (Corynebacterium, Lactobacillus, Actinomyces). Gram-negative rods (Enterobacteriaceae) Gram-negative anaerobic rods (Bacteroides, Prevotella, Porphyromonas, Fusobacterium, Leptotrichia). Gram-positive spore-forming aerobic and anaerobic rods (Bacillus, Clostridia) Mycobacteria. Spirochetes. Rickettsiae. Chlamydiae. Mycoplasma. Medically important fungi Medically important protozoa. Medically important helminths. General virology (cultivation of viruses, cell-virus interactions, serological tests and moleculare techniques used in laboratory diagnosis of viral diseases) Faculty of Dentistry 327
SEMMELWEIS UNIVERSITY / FACULTY OF DENTISTRY 328 Lectures (2 hours per week) Practices (2 hours per week) Arbo- and robovirus infection. Rabies. Slow viruses. Viral infections involving the oral, perioral tissues and salivary glands. Normal oral flora. Oral ecosystem and dental plaque. Microbiology of dental caries, periodontal diseases. Dentoalveolar infections. More than 3 semester absences invalidate the semester. BASIC IMMUNOLOGY Department of Genetics, Cell and Immunobiology Course director: Prof. Dr. András Falus Tutor: A. Kristóf Fülöp, PhD Subject code: FOKGEN037_1A Prerequisite subject: Medical Biochemistry, Molecular and Cell Biology III. Credits: 3 Pathogenesis and symptomatology of viral diseases. Summary of microbiological laboratory techniques and diagnostic procedures. Consultation. Lectures (2 hr / week) Practices / Seminars (1 hr / week) 1. The roles, processes, organs and cells of the immune system Basic terms, organs and cell of the immune system 2 Principles of natural immunity Methods based on antigen-antibody interactions 3. The complement system Flow cytometry 4. Acute phase reaction, neuro- and psychoimmunology Immunoserology 5. Antigen, antigen presentation and MHCs Cell culturing 6. Antigen receptors and their formation Immunization and vaccination 7. T lymphocytes and cell-mediated immune response Migration of immune cells, homing and extravasation 8. B lymphocytes and humoral immune response Screening methods for autoantibodies, HLA typing 9. Hypersensitivity Midterm test 10. Immunology of transplantation and pregnancy Hypersensitivity I. 11. Natural and pathological autoimmunity Hypersensitivity II. 12. Immune response in infections, immunodeficiencies Biological therapies 13. Tumor immunology Immunological databases, prediction servers, simulations 14. Immunopharmacology, immunogenetics and review Case studies The order of lessons may change. Attendance of a minimum of 75% of the lessons is necessary for the end-term signature. Exam: written test in the exam period. Literature: Textbook: Falus A. Immunology, Semmelweis PH, 2001. Hand-out: on www.dgci.sote.hu
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SEMMELWEIS UNIVERSITY / FACULTY OF DENTISTRY<br />
328<br />
Lectures (2 hours per week) Practices (2 hours per week)<br />
Arbo- and robovirus infection. Rabies. Slow viruses.<br />
Viral infections involving the oral,<br />
perioral tissues and salivary glands.<br />
Normal oral flora. Oral ecosystem and dental<br />
plaque. Microbiology of dental caries, periodontal<br />
diseases. Dentoalveolar infections.<br />
More than 3 semester absences invalidate the semester.<br />
BASIC IMMUNOLOGY<br />
Department of Genetics, Cell and Immunobiology<br />
Course director: Prof. Dr. András Falus<br />
Tutor: A. Kristóf Fülöp, PhD<br />
Subject code: FOKGEN037_1A<br />
Prerequisite subject: Medical Biochemistry, Molecular and Cell Biology III.<br />
Credits: 3<br />
Pathogenesis and symptomatology of viral diseases.<br />
Summary of microbiological laboratory techniques<br />
and diagnostic procedures. Consultation.<br />
Lectures (2 hr / week) Practices / Seminars (1 hr / week)<br />
1.<br />
The roles, processes, organs and cells of the immune<br />
system<br />
Basic terms, organs and cell of the immune<br />
system<br />
2 Principles of natural immunity<br />
Methods based on antigen-antibody<br />
interactions<br />
3. The complement system Flow cytometry<br />
4. Acute phase reaction, neuro- and psychoimmunology Immunoserology<br />
5. Antigen, antigen presentation and MHCs Cell culturing<br />
6. Antigen receptors and their formation Immunization and vaccination<br />
7. T lymphocytes and cell-mediated immune response<br />
Migration of immune cells, homing and<br />
extravasation<br />
8. B lymphocytes and humoral immune response<br />
Screening methods for autoantibodies, HLA<br />
typing<br />
9. Hypersensitivity Midterm test<br />
10. Immunology of transplantation and pregnancy Hypersensitivity I.<br />
11. Natural and pathological autoimmunity Hypersensitivity II.<br />
12. Immune response in infections, immunodeficiencies Biological therapies<br />
13. Tumor immunology<br />
Immunological databases, prediction servers,<br />
simulations<br />
14. Immunopharmacology, immunogenetics and review Case studies<br />
The order of lessons may change.<br />
Attendance of a minimum of 75% of the lessons is necessary for the end-term signature.<br />
Exam: written test in the exam period.<br />
Literature:<br />
Textbook: Falus A. Immunology, Semmelweis PH, 2001.<br />
Hand-out: on www.dgci.sote.hu
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