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222<br />

SEMMELWEIS UNIVERSITY / FACULTY OF MEDICINE<br />

ELECTIVE SUBJECTS<br />

(basic/pre-clinical/clinical modules) – curricula<br />

It is compulsory to choose one subject each semester.<br />

BASICS OF MEDICAL CHEMISTRY<br />

Department of Medical Chemistry, Molecularbiology and Pathobiochemistry<br />

Lecturer: Dr. Gábor Bánhegyi<br />

Lectures: compulsory<br />

Credit: 1<br />

Topics:<br />

1: Basics of atomic and molecular structure, periodic table, bondings.<br />

2: Chemical equations, stoichiometry, reaction types. Acids, bases, salts. Solutions.<br />

Concentrations.<br />

3: Laws of diluted solutions. Electrolytes, ionization of electrolytes. Conductivity. Acid-base<br />

theories.<br />

4: Chemical equilibria. Le Chatelier principle, law of mass action. Equilibria in aequous solutions,<br />

principle of pH. Buffers. Carbon dioxide/hydrocarbonate buffer.<br />

5: Consultation: preparation for the 1 st midterm. Focused on calculations: ionization, pH, buffer,<br />

solubility product.<br />

6: Chemical thermodynamics. Principles of enthalpy, entropy, free enthalpy. Hess’ law. Basics of<br />

reaction kinetics. Activation energy and catalysis.<br />

7: Electrochemistry. Oxidation and reduction, redox systems in the living cells.<br />

8: A short summary of inorganic chemistry. Metals and non-metals. Complexes.<br />

9: Calculations in electrochemistry and thermochemistry.<br />

10. Basics of organic chemistry, hybrid states of carbon, organic reaction types. Isomerism,<br />

structural isomerism. IUPAC nomenclature.<br />

11. Stereochemistry. Geometric and chiral isomerism, nomenclature. Prochirality.<br />

12. The most important groups of organic compounds. Aliphatic and aromatic skeletons, their<br />

reactions. Repetitions of their structures. Consultation before the 2 nd midterm – focused on<br />

organic chemistry.<br />

13. The most important groups of organic compounds according their functional groups, their<br />

reactions. Repetitions of their structures.<br />

14: Closing test. 30 multiple choice questions and 10 structures<br />

Exam: closing test. 30 multiple chice questions and 10 structures<br />

Note: Material of the lectures is available on the website of the Department.<br />

Max. 3 absences are allowed.

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