semmelweis university 2 0 1 2 / 2 0 1 3

infections, urinary tract and intraabdominal infections, endocarditis, meningitis, sepsis. Obviously,
the lecturers bring into focus the considerations concerning antibiotic therapy. In the second half
of the course, some of the nosocomial infections, infections of immunocompromised hosts and
zoonoses are discussed, followed by the problems of antibiotic prophylaxis and antibiotic policy.
The course is organized only in the first semester
Course director: Prof. Dr. Endre Ludwig.
The venue of course: Szent László Hospital
1097 Budapest, Gyáli út 5-7. Building N. 19 Lecture Room
Textbooks:
1. E. Ludwig: Antibiotic therapy, Medintel, Budapest, 2003.
2. A. Szalka, L. Tímár, E. Ludwig, Zs. Mészner: Infectology, Medicina, Budapest, 2005.
3. Reese and Betts: A practical approach to infectious diseases. Lippincott Williams and Wilkins 2003.
4. Material of the lectures online availability
2012-2013. 1st semester – Lectures
SEMMELWEIS UNIVERSITY / FACULTY OF MEDICINE
Basic principles of antimicrobial therapy. Microbiological diagnosis, as the basis of antimicrobial
therapy. The concept of “drug of choice”
Diagnosis of infectious diseases: clinical relevance of the various diagnostic tests
Optimisation of antimicrobial therapy. The pk/pd approach, correlation of dosage and clinical
efficacy.
Infectious diseases with exanthemas
Upper respiratory tract infections (common cold, acute and chronic rhinosinusitis, acute otitis,
tonsiliopharyngitis). Epidemiology, the influence of age. Theoretical considerations and practice.
Community acquired pneumonia. Epidemiology, the difficulties of etiological diagnosis. The impact
of emerging bacterial resistance on the clinical efficacy of antibiotics. The modern approach and
practice based on it
The nosocomial infections. Nosocomial pneumonia, difficulties of etiological diagnosis.
Antimicrobial treatment. Iv catheter-associated infections.
Intraabdominal infections (primary and secondary peritonitis, cholecystitis). Urinary tract infections.
Central nervous system infections. Meningitis, etiological diagnosis, antimicrobial treatment.
Infections of the immunocompromised hosts. Diagnosis, and the principles of treatment. Invasive
fungal infections. Colonisation and infection. Treatment of Candida and aspergillus infections.
Tropical diseases. HIV and AIDS.
The modern concept of sepsis. The basis of antimicrobial therapy. Indication of antibiotic
combinations. The toxic shock syndrome.
Important note: Attendance at 70% of the lectures is compulsory. The end semester grade is the
result of the multiple choice test.
Recommended textbooks:
1. Ludwig E. (szerk): Antibiotikum terápia 2003
Medintel, Budapest, 2003.
2. Szalka A., Tímár L., Ludwig E., Mészner Zs. (Szerk.): Infektológia.
Medicina, Budapest, 2005.
3. Reese and Betts: A practical approach to infectious diseases. Lippincott Williams and Wilkins 2003.
4. Figures of the lectures are available elctronically
Faculty of Medicine
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